Extracorporeal ("ex vivo") connection of pig kidneys to humans. I. Clinical data and studies of platelet destruction

Xenotransplantation

Volumn 3, Issue 4, 1996, Pages 328-339

  Breimer, Michael E ^a   Björck, Staffan ^a   Svalander, Christian T ^a   Bengtsson, Anders ^a   Rydberg, Lennart ^a   Lie Karlsen, Kari ^a   Attman, Per Ola ^a   Aurell, Mattias ^a   Samuelsson, Bo E ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Human xenoperfusion; Pig kidney; Platelet destruction; Xenorejection

Indexed keywords

EID: 0001440872     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3089.1996.tb00155.x     Document Type: Article

References (29)

1. COOPER DKC, KEMP E, WHITE DJG eds. Xenotransplantation, the transplantation of organs and tissues between species. Springer Verlag, Berlin, 1991:9.
2. MÖLLER G,ed. Xenotransplantation. Immunological Rev. Munksgaard, Copenhagen, 1994:141:5.
3. WELSH KI, TAUBE DH, THICK M, PALMER A, STEVENS N, BINNS RM. Human antibodies to pig determinants and their association with hyperacute rejection of xenografts. In: Cooper DKC, Kemp E, White DJG, eds. Xenotransplantation, the transplantation of organs between species. Springer Verlag, Berlin, 1991:501.
4. CAIRNS TDH, TAUBE DH, STEVENS N, BINNS R, WELSH KI. Xenografts-future prospects for clinical transplantation. Immunological Lett 1991:29:167.
5. SAMUELSSON BE, RYDBERG L, BREIMER ME, et al. Natural antibodies and human xentransplantation. Immunol Rev. 1994:141:151.
6. RYDBERG L, HALLBERG E, BJÖRCK S, et al. Studies on the removal of anti-pig xenoantibodies in the human by plasmapheresis/immunoadsorption. Xenotransplantation 1995:2:253.
7. BREIMER ME, SVALANDER CT, HARALDSSON B, BJÖRCK S. Physiological and histological characterisation of a pig kidney in vitro perfusion model for xenotransplantation studies. Scand J Urol Nephrol 1996:30:213.
8. GYRD-HANSEN N. Renal clearance in pigs. Acta Vet Scand 1968:9:183.
9. PLATT LP, FISCHEL RJ, MATAS AJ, REIF SA, BOLMAN RM, BACH FH. Immunopathology of hyperacute xenograft rejection in a swine-to-primate model. Transplantation 1991:52:214-220.
10. RIEBEN R, VON ALLMEN E, KORCHAGINA EY, et al. Detection, immunoabsorption, and inhibition of cytotoxic activity of anti-αGal antibodies using newly developed substances with synthetic Galα1-3Gal Disaccharide epitopes Transplantation 1995:2:98.
11. CAIRNS T, LEE J, GOLDBERG L, et al. Inhibition of the pig to human xenograft reaction using soluble Galα1-3Gal and Galα1-3Galβ1-4GlcNAc. Transplantation 1995:60:1202.
12. PRUITT SK, KIRK AD, BOLLINGER RR, et al. The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts. Transplantation 1994:57:363.
13. KROSHUS TJ, ROLLINS SA, DALMASSO AP, et al. Complement inhibition with an anti-C5 monoclonal antibody prevents acute cardiac tissue injury in an ex vivo model of pig to human xenotransplantation. Transplantation 1995:60:1194.
14. YE Y, NEETHLING FA, NIEKRASZ M, et al. Evidence that intraveneously administrated α-Galactosyl carbohydrates reduce baboon serum cytotoxicity to pig kidney cells (PK15) and transplanted hearts. Transplantation 1994:58:330.
15. PLATT JL, BACH FH. The barrier to xenotransplantation. Transplantation 1991:52:937.
16. AUCHINCLOSS H Jr. Xenogenic transplantation: A review. Transplantation 1988:46:1.
17. CRAMER DV, SHER L, MAKOWKA L. Liver xenotransplantation: Clinical experience and future considerations. In: Cooper DKC, Kemp E, White DJG, eds. Xenotransplantation, the transplantation of organs between species. Springer Verlag, Berlin, 1991:559.
18. CHARI RS, COLLINS BH, MAGEE JC, et al. Brief report: Treatment of hepatic failure with ex vivo pig liver perfusion followed by liver transplantation. N Engl J Med 1994:331:234.
19. MAKOWKA L, CRAMER DV, HOFFMAN A, et al. The use of a pig liver xenograft for temporary support of a patient with fulminant hepatic failure. Transplantation 1995:59:1654.
20. COLLINS BH, CHARI RS, MAGEE JC, et al. Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure. Transplantation 1994:58:1162.
21. COTTERELL AH, COLLINS BH, PARKER W, HARLAND RC, PLATT JL. The humoral immune response in humans following cross perfusion of porcine organs. Transplantation 1995:60:861.
22. ROSENGARD AM, CARY NRB, LANGFORD GA, TUCKER AW, WALLWORK J, WHITE DJG. Tissue expression of human complement inhibitor, decay-accelerating factor, in transgenic pigs. Transplantation 1995:59:1325.
23. RYDBERG L, BJÖRCK S, HALLBERG E, et al. Extra corporeal ("ex vivo") connection of pig kidneys to humans II. The antipig antibody response. Xenotransplantation 1996;0:000 (Manuscript 96-24).
24. ORIOL R, YONG Y, KOREN E, COOPER DKC. Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation. Transplantation 1993:56:1433.
25. MICHAELS MG, SIMMONS RL. Xenotransplantation associated zoonoses: Strategies for prevention. Transplantation 1994:57:1.
26. YE Y, NIEKRASZ M, KOSANKE S, et al. The pig as a potential organ donor for man: A study of potentially transferable disease from donor pig to recipient man. Transplantation 1994:57:694.
27. FISHMAN JA. Miniature swine as organ donors for man: Strategies for prevention of xenotranplant-associated infections. Xenotransplantation 1994:1:47.
28. CHAPMAN LE, FOLKS TM, SALMON DR, PATTERSON AP, EGGERMAN TE, NOGUCHI PD. Xenotransplantation and xenogenic infections. N Engl J Med 1995:333:1498.
29. GROTH CG, KURSGREN O, TIBELL A, et al. Transplantation of porcine fetal pancreas to diabetic patients. Lancet 1994:344:1402.