Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model (Plasma clearance)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 84, Issue 6, 1987, Pages 1487-1491

  Katre, N V ^a   Knauf, M J ^a   Laird, W J ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; MACROGOL; RECOMBINANT INTERLEUKIN 2;

ANIMAL MODEL; CHEMICAL MODIFICATION; CHROMATOGRAPHY; DRUG SYNTHESIS; GENETIC ENGINEERING; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; SARCOMA; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA; ESCHERICHIA COLI; MURINAE;

EID: 0001365675     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.84.6.1487     Document Type: Article

References (0)