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As presently configured, the vapor-flow cell requires that the IR beam interact with both vapor-phase base molecules in the cell headspace and molecules bound to the substrate (see ref 7). However, we have recently constructed a polarization-modulation FTIR apparatus that will permit vibrational analysis of only the surface-confined molecules in the presence of the dosing vapor. (See: Green, M. J.; Barner, B. J.; Saez, E. I.; Corn, R. M. Anal. Chem, 1991, 63, 55.)
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