Optical biopsy fiber based fluorescence spectroscopy instrumentation

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 2679, Issue , 1996, Pages 118-123

  Katz, Alvin ^a   Ganesan, Singaravelu ^a   Yang, Yuanlong ^a   Tang, Gui C ^a   Budansky, Yury ^a   Celmer, Edward J ^c   Savage, Howard E ^b   Schantz, Stimson P ^b   Alfano, Robert R ^a  

^a CITY COLLEGE OF NEW YORK   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c ST VINCENT S HOSPITAL   (United States)

Author keywords

Fluorescence instrumentation; Fluorescence mapping; Optical biopsy; Photonic pathology

Indexed keywords

BIOPSY; CONFORMAL MAPPING; DATA STORAGE EQUIPMENT; EMISSION SPECTROSCOPY; FIBERS; FLUORESCENCE; INSTRUMENTS; LIGHT; MEDICINE; OPTICAL FIBERS; OPTICAL MATERIALS; PATHOLOGY;

BENIGN TISSUES; BREAST CANCERS; CANCER.; CANCEROUS TISSUES; CLINICAL SETTINGS; EMISSION INTENSITIES; EMISSION SPECTRAL; FIBER PROBES; FLUORESCENCE MAPPING; HIGH ACCURACIES; HIGH SENSITIVITIES; HUMAN TISSUES; IN-VIVO; MALIGNANT TISSUES; MEDICAL COMMUNITIES; NATIVE FLUORESCENCES; NEW MODALITIES; NORMAL TISSUES; OPTICAL BIOPSY; OPTICAL FIBER PROBES; PHYSIOLOGICAL CONDITIONS; SMALL DIAMETERS; SPATIAL RESOLUTIONS; SPECTROSCOPIC METHODS; SPECTROSCOPY INSTRUMENTATIONS; ULTRAVIOLET EXCITATIONS;

TISSUE;

EID: 0001334496     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.237579     Document Type: Conference Paper

References (12)

1. R. R. Alfano, D. B. Tata, J. J. Cordero, P. Tomashefsky, F. W. Longo, and M. A. Alfano, "Laser induced fluorescence spectroscopy from native cancerous and normal tissues." IEEE J. Quantum Electron QE-20, 1507-1511 (1984).
2. R. R. Alfano, G. C. Tang, A. Pradhan, W.Lam. D. S. J. Choy, and E. Opher, "Fluorescence spectra from cancerous and normal human breast and lung tissues." IEEE J. Quantum Electron QE-23, 1806 (1987).
3. G. C. Tang, A. Pradhan and R. R. Alfano, "Spectroscopic differences between human cancer and normal lung and breast tissues." Lasers Surg. Med. 9: 290-295 (1989).
4. G.C. Tang, A. Pradhan, Wenling Sha, J. Chen, C.H. Liu, S.J. Wahl and R.R. Alfano, Pulsed and cw laser fluorescence spectra from cancerous, normal and chemically treated human breast and lung tissues, Applied Optics 28:2337 (1989).
5. K. T. Shomacker, J. K. Frisoli, C. C. Compton, T. J. Flotte, J. M. Richter, N. S. Nishioka and T. F. Deutsch, "Ultraviolet laser induced fluorescence of colonic tissue: Basic biology and diagnostic potential." Lasers Surg. Med. 12, 63-78 (1992).
6. R.E. Petras, R.R. Kortum, L. Tong, M. Fitzmaurice, M. Feld and M. Sivak, Fluorescence spectroscopy of colonic adenomas: implications for an endoscopic laser diagnostic system. Gastrointest. Endosc. 35:181 (1989).
7. Y. Yang, G.C. Tang, M. Bessler and R.R. Alfano, Fluorescence spectroscopy as a photonic pathology method for detecting colon cancer, Lasers in the Life Sci. 6:259-276 (1995).
8. W. Sha Glassman, C.H. Liu, G.C. Tang, S. Lubicz and R.R. Alfano, Ultraviolet excited fluorescence spectra from non-malignant and malignant tissues of the gynecological tract, Lasers in the Life Sciences 5:49 (1992).
9. N. Ramanujam, M.F. Mitchell, A. Mahadevan, S. Thomsen, E. Silva and R. Richards-Kortum, Fluorescence spectroscopy: A diagnostic tool for cervical intraepithelial neoplasia (CIN), Gynecologic Oncology, 52:31-38 (1994).
10. G.C. Tang, H.E. Savage, M. Silverberg, P.G. Sacks, V. Ried, S.P. Schantz and R.R. Alfano, Native fluorescence spectroscopic detection of the effects of chemotherapeutic retinoids on a cancer model of the aerodigestive tract, in: "Optics for protection of man and environment against natural and technological disasters", G. von Bally and H. I. Bjelkhagen ed.Elsevier Science Publisher, (1993).
11. R. Glasgold, M. Glasgold, H. Savage, J. Pinto, R.R. Alfano and S. Schantz, Tissue autofluorescence as an intermediate endpoint in NMBA-induced esophageal carcinogenesis, Cancer Letters, 82, 33 (1994).
12. Y. Yang, E. J. Celmer, M. Zurawska-Szczepaniak and R. R. Alfano, "Optical Spectroscopy of breast benign and malignant tissues," Submitted to SPIE, BIOS '96.