Formal synthesis of (±)-pancracine using stereoselective radical cyclization of N-(2-cyclohexenyl)-α-aryl-α-(phenylthio)acetamide

Synlett

Volumn , Issue 11, 1998, Pages 1246-1248

  Ikeda, Masazumi ^a   Hamada, Masahiro ^a   Yamashita, Takashi ^a   Ikegami, Fumi ^a   Sato, Tatsunori ^a   Ishibashi, Hiroyuki ^b  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001263329     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1937     Document Type: Article

References (23)

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13. (e) Ishibashi, H.; Higuchi, M.; Ohba, M.; Ikeda, M. Tetrahedron Lett. 1998, 39, 75.
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19. It is known that 3-phenyloctahydroindol-2-one having cis-stereochemistry of two hydrogen atoms between 3- and 3a-positions, on treatment with EtONa in boiling EtOH, isomerizes to the thermodynamically more stable corresponding trans-isomer. See: ref 6.
20. Ishibashi, H.; Ikeda, M.; Choi, H.D.; Nakagawa, H.; Ueda, Y.; Tamura, Y. Chem. Pharm. Bull. 1985, 33, 5310 and references cited therein.
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23. 1H NMR spectrum of 25.