Significance thresholds for QTL interval mapping tests

Heredity

Volumn 76, Issue 5, 1996, Pages 459-464

  Doerge, R W ^a   Rebaï, Ahmed ^b  

^a PURDUE UNIVERSITY   (United States)

^b CEMAGREF   (France)

Author keywords

Interval mapping; Molecular marker; QTL; Threshold values

Indexed keywords

EID: 0001262225     PISSN: 0018067X     EISSN: None     Source Type: Journal    
DOI: 10.1038/hdy.1996.68     Document Type: Article

References (17)

1. CHURCHILL, G. A. AND DOERGE, R. W. 1994. Empirical threshold values for quantitative trait mapping. Genetics, 138, 963-971.
2. DUPUIS, J. 1994. Statistical Problems Associated with Mapping Complex and Quantitative Traits from Genomic Mismatch Scanning Data. Ph.D. Thesis, Stanford University, Department of Statistics.
3. FEINGOLD, E., BROWN, P. O. AND SIEGMUND, D. 1993. Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am. J. Hum. Genet., 53, 234-251.
4. FISHER, R. A. 1935. The Design of Experiments, 3rd edn. Oliver and Boyd, London.
5. HALEY, C. S. AND KNOTT, S. A. 1992. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity, 69, 315-324.
6. HALEY, C. S., KNOTT, S. A. AND ELSEN, J. M. 1994. Mapping quantitative trait loci in crosses between outbred lines using least squares. Genetics, 136, 1195-1207.
7. JANSEN, R. C. 1994. Controlling the type I and type II errors in mapping quantitative trait loci. Genetics, 138, 871-881.
8. JANSEN, R. C. AND STAM. P. 1994. High resolution of quantitative traits into multiple loci via interval mapping. Genetics, 136, 1447-1455.
9. KRUGLYAK, L. AND LANDER, E. S. 1995. A nonparametric approach for mapping quantitative trait loci. Genetics, 139, 1421-1428.
10. LANDER, E. S. AND BOTSTEIN, D. 1989. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics, 121, 185-199.
11. LANDER, E. S. AND BOTSTEIN, D. 1994. Corrigendum. Genetics, 36, 705.
12. MANGIN, B., GOFFINET, B. AND REBAÏ, A. 1994. Constructing confidence intervals for QTL location. Genetics, 138, 1301-1308.
13. REBAÏ, A., GOFFINET, B. AND MANGIN B. 1994b. Approximate thresholds of interval mapping tests for QTL detection. Genetics, 138, 235-240.
14. REBAÏ, A., GOFFINET, B. AND MANGIN, B. 1995. Comparing powers of different methods for QTL detection. Biometrics, 51, 87-99.
15. REBAÏ, A., GOFFINET, B., MANGIN, B. AND PERRET, D. 1994a. QTL detection with diallel schemes. In: Proceedings of the Ninth Eucarpia Meeting. Molecular markers in Plant Breeding, pp. 170-177. Wageningen.
16. ZENG, Z.B. 1993. Theoretical basis for separation of multiple linked gene effects in mapping quantiative trait loci. Proc. Natl. Acad. Sci. U.S.A., 90, 10972-10976.
17. ZENG, Z.-B. 1994. Precision mapping of quantitative trait loci. Genetics, 136, 1457-1468.