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Fluoride anion: Noyori, R.; Yokoyama, K.; Kuwajima, I.; Nakamura, E.; Sakata, J. J. Am. Chem. Soc. 1977, 99, 1265.
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Tetrahedron 1983, 39, 117.
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Combinations of tin(II) chloride or triflate with neutral molecule or Lewis acid
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0001118685
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The mechanism of the catalyzed Mukaiyama-Aldol and -Michael reactions are not definitively established. It seems generally accepted that aldol-type reactions in aprotic solvents occur through enolates possessing a Lewis acidic metal counterion via a six-membered chelate transition state (ref 6a and references cited therein). The intervention of Lewis acid mediated electron transfer in the Mukaiyama-Michael reaction has been recently suggested, and references cited therein
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The mechanism of the catalyzed Mukaiyama-Aldol and -Michael reactions are not definitively established. It seems generally accepted that aldol-type reactions in aprotic solvents occur through enolates possessing a Lewis acidic metal counterion via a six-membered chelate transition state (ref 6a and references cited therein). The intervention of Lewis acid mediated electron transfer in the Mukaiyama-Michael reaction has been recently suggested: Sato, T.; Wakahara, Y.; Otera, J.; Nozaki, H. J. Am. Chem. Soc. 1991, 113, 4028 and references cited therein.
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