Differential role of tyrosine phosphorylation in the induction of apoptosis in T cell clones via CD95 or the TCR/CD3-complex

Cell Death and Differentiation

Volumn 4, Issue 5, 1997, Pages 403-412

  Oberg, Hans Heinrich ^a   Lengl Janßen, Beate ^a   Robertson, Michael J ^b   Kabelitz, Dieter ^a   Janssen, Ottmar ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; CD95; Human; Signal transduction; T cell receptor; T lymphocytes; Tyrosine phosphorylation

Indexed keywords

EID: 0001251837     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400256     Document Type: Article

References (34)

1. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itho N, Shibuya M and Fukami Y (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262: 5592-5595
2. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F and Lynch DH (1995) Fas ligand mediates activation-induced cell death in human T lymphocytes. J. Exp. Med. 181: 71-77
3. Anel A, Buferne M, Boyer C, Schmitt-Verhulst AM and Golstein P (1994) T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A. Eur. J. Immunol. 24: 2469-2476
4. fynT. J. Biol. Chem. 271: 5968-5971
5. Boldin MP, Goncharov TM, Goltsev YV and Wallach D (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease in Fas/APO-1- and TNF Receptor-induced cell death. Cell 85: 803-81
6. Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF and Green DR (1995) Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373: 441-444
7. Cifone MG, De Maria R, Roncaioli P, Rippo MR, Azuma M, Lanier LL, Santoni A and Testi R (1994) Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 180: 1547-1552
8. Chinnaiyan AM, O'Rourke K, Tewari M and Dixit VM (1995) FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81: 505-512
9. Dhein J, Daniel PT, Traut BC, Oehm A, Möller P and Krammer PH (1992) Induction of apoptosis by monoclonal anti-APO-1 class switch variants is dependent on crosslinking of APO-1 cell surface antigens. J. Immunol. 149: 3166-3173
10. Dhein J, Walczak H, Baeumler C, Debatin KM and Krammer PH (1995) Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373: 438-441
11. Dobrowsky RT, Kamibayashi C, Mumby MC and Hannun YA (1993) Ceramide activates heterotrimeric protein phosphatase 2A. J. Biol. Chem. 268: 15523-15530
12. Dressler KA, Mathias S and Kolesnik RN (1992) Tumor necrosis factor alpha activates the shingomyelin signal transduction pathway in a cell free system. Science 255: 1715-1718
13. Eischen CM, Dick CJ and Leibson PJ (1994) Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J. Immunol. 153: 1947-1954
14. Gazit A, Yaish P, Gilon C and Levitzki A (1989) Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J. Med. Chem. 32: 2344-2352
15. Gill BM, Nishikata H, Chan G, Delovitch TL and Ochi A (1994) Fas antigen and sphingomyelin-ceramide turnover-mediated signaling: role in life and death of T lymphocytes. Immunol. Rev. 142: 113-125
16. Golstein P, Mattei MG, Foa C and Luciani MF (1994) Molecular mechanisms of T lymphocyte cytotoxicity. In Apoptosis and the immune response. Gregory CD, ed (New York; John Wiley and Sons) pp 143-168
17. Gulbins E, Bissonnette R, Mahboubi A, Martin S, Nishioka W, Brunner T, Baier G, Baier-Bitterlich G, Byrd C, Lang F, Kolesnik R, Altman Aand Green D (1995) FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity 2: 341-351
18. Hane M, Lowin B, Peitsch M, Becker K and Tschopp J (1995) Interaction of peptides derived from the Fas ligand with the Fyn SH3 domain. FEBS Letters 373: 265-268
19. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S-I, Sameshima M, Hase A, Seto Y and Nagata S (1991) The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66: 233-243
20. + T cells. J. Immunol. 146: 35-39
21. Raines MA, Kolesnik RN and Golde DW (1993) Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells. J. Biol. Chem. 268: 14572-14575
22. 2+ independent T cell-mediated cytotoxicity. J. Exp. Med. 177: 195-200
23. Rudd CE, Janssen O, Cai J-C, da Silva AJ, Raab M and Prasad KVS (1994) Two-step TCR/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases. Immunol. Today 15: 225-234
24. Russel JH (1995) Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7: 382-388
25. Sato T, Irie S, Kitada S and Reed JC (1995) FAP-1: a protein tyrosine phosphatase that associates with Fas. Science 268: 411-415
26. Schraven B and Peter ME (1995) APO-1 (CD95)-mediated apoptosis in Jurkat cells does not involve src kinases or CD45. FEBS Letters 368: 491-494
27. Schütze S, Potthoff K, Machlaidt D, Berkovic D, Wiegmann K and Krönke M (1992) TNF activates NF-kappa B by phosphatidylcholine-specific phopholipase C-induced 'acidic' sphingomyeline breakdown. Cell 71: 765-776
28. Schulze-Osthoff K, Walczak H, Droege W and Krammer PH (1994a) Cell nucleus and DNA fragmentation are not required for apoptosis. J. Cell. Biol. 127: 15-20
29. Schulze-Osthoff K, Krammer PH and Droege W (1994b) Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. EMBO J. 13: 4587-4596
30. + T cell-mediated cytotoxicity. J. Immunol. 152: 1127-1133
31. Stanger BZ, Leder P, Lee TH, Kim E and Seed B (1995) RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81: 513-523
32. Suda T and Nagata S (1994) Purification and characterization of the Fas-ligand that induces apoptosis. J. Exp. Med. 179: 873-879
33. ++-dependent protein kinase. Biochem. Biophys. Res. Commun. 135: 397-402
34. Taupin JL, Tian Q, Kedersha N, Robertson M and Anderson P (1995) The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death. Proc. Natl. Acad. Sci. USA 92: 1629-1633