Platelets from patients with Alzheimer's disease or other dementias exhibit disease-specific and apolipoprotein E correctable defects

Amyloid

Volumn 3, Issue 1, 1996, Pages 13-19

  Davies, Theresa A ^a,c   Long, Heidi J ^a   Rathbun, Wayne H ^a   Sgro, Kimberly R ^a   Tibbles, Heather ^a   Smith, Sally J ^b   Seetoo, Kurt F ^a   McMenamin, Mary E ^a   Johnson, Robin ^a   Wells, John M ^b   Levesque, Claire ^c   Fine, Richard E ^a,b   Simons, Elizabeth R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Psychology Service   (United States)

^c BOSTON MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; A PP; Cytoplasmic pH; Platelet; Surface markers

Indexed keywords

EID: 0001251237     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129609014350     Document Type: Article

References (36)

1. Selkoe DJ (1994). Alzheimer's disease: A central role for amyloid. J Neuropath and Exp Neurol 53, 438-447
2. Yankner BA and Mesulam MM (1991). Beta amyloid and the pathogenesis of Alzheimer's disease. N Engl J Med 325, 1849-1857
3. Younkin SG (1991). Processing of Alzheimer's disease ß/ A4 amyloid precursor protein. Brain Path 1, 253-262
4. Selkoe DJ (1993). Physiological production of ß amyloid peptide and mechanism of Alzheimer's disease. Trends in Neurol Sci 16, 403-409
5. Selkoe DJ (1991). Amyloid protein and Alzheimer's disease. Neuron 6, 487-498
6. Mann DMA, Yuonis N, Jones D and Stoddar RW (1992). Time course of pathological events in Down syndrome with particular reference to involvement of microglial cells and deposits of ß/A4 peptide. Neurodegen 1, 201-15
7. Chui HC (1989). Dementia: A review emphasizing the clinicopathological consequences and brain-behavior relationships. Arch Neurol 46, 806-814
8. Farlow M, Ghetti B, Benson MD, Farrow JS, Van Nostrand WE and Wagner SL (1992). Low cerebrospinal fluid concentration of soluble amyloid ß precursor protein in hereditary Alzheimer's disease. Lancet 340, 453-454
9. Prior R, Monning U, Schreiter-Gasser U, Weidemann A, Blennow K, Gottfries CG, Masters CL and Beyreuther K (1991). Quantitative changes in amyloid precursor protein in Alzheimer's disease cerebrospinal fluid. Neuroscience Lett 124, 69-73
10. Van Nostrand WE, Wagner SL, Shankle WR, Farrow JS, Dick M, Rozemuller JM, Kuiper MA, Wolters EC, Zimmerman J, Cotman CW and Cunningham DD (1992). Decreased levels of soluble amyloid precursor protein in cerebrospinal fluid of Alzheimer's disease patients. Proc Natl Acad Sci 89, 2551-2555
11. Bush AI, Martins RN, Rumble B, Moir R, Fuller S, Milward E, Currie J, Ames D, Weidemann A, Fischer P, Multhaup G, Beyreuther K and Masters CL (1990). The amyloid precursor protein of Alzheimer's disease is released by human platelets. J Biol Chem 265, 15977-15983
12. Bush AI, Whyte S, Thomas LD, Williamson TG, Van Tiggelen CJ, Currie J, Small DH, Moir RD, Li QX, Rumble B, Monning U, Beyreuther K and Masters CL (1992). An abnormality in plasma amyloid precursor protein in Alzheimer's disease. Ann Neurol 32, 57-65
13. Podlisny MB, Mammen A, Schlossmacher MG, Palmert MR, Younkin S G and Selkoe DJ (1990). Determination of soluble forms of ß amyloid precursor protein in human plasma. Biochem Biophys Res Commun 167, 1094-1101
14. Gardella JE, Ghiso J, Gorgone GA, Marratta D, Kaplan AP, Frangione B and Gorevic PD (1990). Intact amyloid precursor protein is present in platelet membranes and is encoded by platelet mRNA. Biochem Biophys Res Commun 173, 1292-1298
15. Van Nostrand W, Schmaier A, Farrow J and Cunningham D (1990). Protease nexin II (Amyloid precursor protein): A platelet α-granule protein. Science 248, 745-748
16. Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D, Sinha S, Schlossmacher M, Whaley J, Swindlehurst C, McCormack R, Wolfert R, Selkoe D, Lieberburg I and Schenk D (1992). Isolation and quantification of soluble Aß peptide from biological fluids. Nature 359, 325-327
17. Cole, GM, Galasko D, Shapiro IP and Saitoh T (1990). Stimulated platelets release amyloid ß-precursor protein. Biochem Biophys Res Commun 170, 288-295
18. Van Nostrand WE, Wagner SL, Farrow JS and Cunningham DD (1990). Immunopurification of protease inhibitory properties of protease nexin II (APP). J Biol Chem 265, 9591-9594
19. Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski B, Lieberburg I, Koo EH, Schenk D, Teplow DB and Selkoe DJ (1992). Amyloid ß peptide is produced by cultured cells during normal metabolism. Nature 359, 322-325
20. Haass C, Hung AY, Schlossmacher MG, Teplow DB and Selkoe DJ (1993). ß amyloid peptide and a 3kDa fragment are derived by distinct cellular mechanisms. J Biol Chem 268, 3021-3024
21. Wisniewski H, Frackowiak J, Zoltowska A and Kim K (1994). Vascular ß amyloid in Alzheimer's disease is produced by proliferating and degenerating smooth muscle cells. Amyloid. Int J Exp Clin Invest 1, 8-16
22. Van Nostrand W, Rozemuller A, Chung R, Cotman C and Saporito-Irwin S (1994). Amyloid ß precursor protein in cultured leptomeningeal smooth muscle cells. Amyloid. Int J Exp Clin Invest 1, 1-7
23. Page CP (1991). Platelet activation. J Lipid Mediators 4, 1-4
24. Rink TJ and Hallam TJ (1984). What turns platelets on? Trends in Biochem. Sci 9, 215-219
25. Zucker MJ and Nachmias VT (1985). Platelet activation. Arteriosclerosis 5, 2-8
26. Stenberg P, McEver R, Shuman M, Jacques Y and Bainton D (1985). A platelet α-granule membrane protein (GMP-140) is expressed in platelet membranes after activation. J Cell Biol 101, 880-886
27. Berman C, Yeo E, Wencel-Drake J, Furie B, Ginsberg M and Furie B (1986). A platelet α-granule membrane protein that is associated with plasma membrane after activation. J Clin Invest 78, 130-137
28. Davies TA, Fine RE, Johnson RJ, Levesque CA, Rathbun WH, Seetoo KF, Smith, SJ, Stromeier G, Volice RL, Delva L and Simons ER (1993). Non age-related differences in thrombin responses by platelets from male patients with advanced Alzheimer's disease. Biochem Biophys Res Commun 194, 537-543
29. Strittmatter WJ, Weisgraber KH, Huang D, Dong L, Salvesen G, Pericak-Vance M, Schmechel D, Saunders A, Goldgaber D and Roses A (1993). Binding of human ApoE to synthetic Aß peptide. Proc Natl Acad Sci 90, 8098-8102
30. Saunders A, Schmader K, Breitner J, Benson M, Brown W, Goldfarb L, Goldgaber D, Manwaring M, Szymanski M, McCown N, Pole KC, Schmechel DE, Strittmatter WJ, Pericak-Vance HA and Roses AD (1993). ApoE4 distribution in late onset Alzheimer's disease and other amyloid-forming diseases. Lancet 342, 710-711
31. Roses A (1994). ApoE affects the rate of Alzheimer's disease expression. J Neuropathol Exp Neurol 53, 429-437
32. Khachaturian ZS (1985). Diagnosis of Alzheimer's disease. Arch Neurology 42, 1097-1105
33. McKhann G, Drachman D, Folstein M, Katzman R, Price D and Stadlan EM (1984). Clinical diagnosis of Alzheimer's disease. Neurology 34, 939-944
34. Whenham P, Price W and Blundel G (1991). ApoE genotyping by one step PCR. Lancet 337, 1158-1159
35. Davies TA, Katona E, Vasilescu V, Cragoe E Jr. and Simons ER (1987). Sequential sodium-proton exchange in thrombin-induced human platelets. Biochem Biophys Acta 903, 381-387
36. Greenberg-Sepersky SM and Simons ER (1984). Cation gradient dependence of the steps in thrombin stimulation of human platelets. J Biol Chem 259, 1502-1508