Non-standard amino acids in peptide design and protein engineering

Current Opinion in Structural Biology

Volumn 2, Issue 6, 1992, Pages 845-851

  Balaram, Padmanabhan ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001210551     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-440X(92)90110-S     Document Type: Article

References (51)

1. Medicinal Chemistry in the Golden Age of Biology: Lessons from Steroid and Peptide Research
2. The Ramachandran Plot and Beyond: Conformational and Topographical Considerations in the Design of Peptides and Proteins
3. De novo Protein Design: What Are We Learning?
4. A General Method for Incorporation of Unnatural Amino Acids into Proteins
5. Site Specific Incorporation of Novel Backbone Structures into Proteins
6. Total Chemical Synthesis of a d-Enzyme: the Enantiomers of HIV-1 Protease Show Demonstration of Reciprocal Chiral Substrate Specificity
7. Constructing Proteins by Dovetailing Unprotected Synthetic Peptides: Backbone-engineered HIV Protease
8. Emerimicins III and IV and their Ethylalanine Epimers. Facilitated Chemical-enzymatic Synthesis and a Qualitative Evaluation of their Solution Structures
9. Helix Formation in Enzymatically Ligated Peptides as a Driving Force for the Synthetic Reaction: Example of α-Globin Semisynthetic Reaction
10. Incorporation of Modified Amino Acids into Proteins in vivo
11. Biosynthesis of a Protein Containing a Nonprotein Amino Acid by Escherichia coli: l-2-Aminohexanoic Acid at Position 21 in Human Epidermal Growth Factor
12. Nonprotein Amino Acid Furanomycin, Unlike Isoleucine in Chemical Structure, Is Charged to Isoleucine tRNA by Isoleucyl-tRNA Synthetase and Incorporated into Protein
13. A General and Efficient Route for Chemical Aminoacylation of Transfer RNAs
14. Site-specific Incorporation of Non-natural Residues into Peptides: Effect of Residue Structure on Suppression and Translational Efficiencies
15. Preparation of Chemically Misacylated Semisynthetic Non-sense Suppressor tRNAs Empolyed in Biosynthetic Incorporation of Non-natural Residues into Proteins
16. Selenoprotein Synthesis: an Expansion of the Genetic Code
17. Site-specific Mutagenesis with Unnatural Amino Acids
18. Zervamicins, a Structurally Characterised Peptide Model for Membrane Ion Channels
19. 1] Zervamicin, a Membrane Ion-channel Peptide: Implications for Gating Mechanisms
20. The Stereochemistry of α-Aminoisobutyric Acid Containing Peptides
21. Structural Characteristics of α-Helical Peptide Molecules Containing Aib Residues
22. Folding Aggregation and Molecular Recognition in Peptides
23. n Sequential Peptides
24. Helix Construction Using α-Aminoisobutyryl Residues in a Modular Approach to Synthetic Protein Design. Conformational Properties of an Apolar Decapeptide in Two Different Crystal Forms and in Solution
25. The Design and Construction of Synthetic Protein Mimics
26. Modular Design of Synthetic Protein Mimics. Crystal Structure of Two Seven-residue Helical Peptide Segments Linked by ε-Aminocaproic Acid
27. Principles and Patterns of Protein Conformation
28. Three Dimensional Structure of an Angiotensin II-Fab Complex at 3 Å: Hormone Recognition by an Anti-idiotypic Antibody
29. The Fully Extended Polypeptide Conformation
30. A Helical Dog Homopeptide
31. 7c). Crystal Structures of Model Peptides
32. New Developments in the Chemoenzymatic Production of Amino Acids
33. Preferred Conformations of Pipecolic Acid Containing Peptides
34. Structure of N-tert-Butyloxycarbonyl-α-aminoisobutyrl-dl-pipecolyl-α-aminoisobutyric Acid Methyl Ester
35. Dehydroamino Acids and Peptides
36. Crystal and Molecular Structure of the Doubly Unsaturated Dehydropeptide Ac-ΔPhe-Ala-ΔPhe-NHMe
37. Effects of Dehydroalanine on Peptide Conformations
38. 2-NH propyl
39. Crystal State Conformation of Three Model Monomer Units for the β-Bend Ribbon Structure
40. The Helix Forming Propensity of d-Alanine in a Right-handed α-Helix
41. A Racemic Protein
42. The Helical S Constant for Alanine in Water Derived from Template-nucleated Helices
43. 1-OH)
44. Synthesis and Conformational Analysis of Epindolidione Derived Peptides. Models for β-Sheet Formation
45. Template-assembled Synthetic Proteins with Four Helix Bundle Topology. Total Chemical Synthesis and Conformational Studies
46. Design of an Artificial Four-helix Bundle Metalloprotein via a Novel Ruthenium (II) Assisted Self-assembly Process
47. Iron (II) Organises a Synthetic Peptide into Three-helix Bundles
48. A Convergent Approach to Protein Design. Metal Ion-assisted Spontaneous Self-assembly of a Polypeptide into a Triple-helix Bundle Protein
49. Probing Protein Stability with Unnatural Amino Acids
50. General Approach to the Synthesis of Short α-Helical Peptides
51. Sequential Site-directed Mutagenesis and Chemical Modification to Convert the Active Site Agrinine 292 of Aspartate Aminotransferase to Homoarginine