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The separation of the diastereomers was carried out by column chromatography using mixture of 60%EtOAc and 40% hexane as eluent to give 9 (0.20 g) and 10 (0.26 g) as white solids (combined yield 93%).
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25
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note
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Some phospholes bearing heteroaromatic substituents at phosphorus have been prepared. Lithium phospholide reacts with 2-bromopyridine or 2-bromophosphinine generally in the presence of Pd(0) or Ni(0) catalysts to give the corresponding 1-pyridinylphosphole and 1-phosphininylphosphole. The reaction takes place also without a catalyst.
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