Fast-HMQC using Ernst angle pulses: An efficient tool for screening of ligand binding to target proteins

Journal of Biomolecular NMR

Volumn 10, Issue 4, 1997, Pages 389-396

  Ross, Alfred ^a   Salzmann, Michael ^a   Senn, Hans ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Ernst angle; HMQC; Ligand binding; Screening (SAR); SH3

Indexed keywords

EID: 0001201663     PISSN: 09252738     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018361214472     Document Type: Article

References (41)

1. Aue, W.P., Bartholdi, E. and Ernst, R.R. (1976a) J. Chem. Phys., 64, 2229-2246.
2. Aue, W.P., Karhan, J. and Ernst, R.R. (1976b) J. Chem. Phys., 64, 4226.
3. Barker, P. and Freeman, R. (1985) J. Magn. Reson., 64, 334-338.
4. Bax, A., Griffey, R.H. and Hawkins, B.L. (1983) J. Magn. Reson., 55, 301-315.
5. Bax, A. and Davis, D.G. (1985a) J. Magn. Reson., 63, 207-213.
6. Bax, A. and Davis, D.G. (1985b) J. Magn. Reson., 65, 355-360.
7. Bodenhausen, G. and Ruben, D.J. (1980) Chem. Phys. Lett., 69, 185-188.
8. Bodenhausen, G., Kogler, H. and Ernst, R.R. (1984) J. Magn. Reson., 58, 370-388.
9. Bothner-By, A.A., Stephens, R.L., Lee, J.-M., Warren, C.D. and Jeanloz, R.W. (1984) J. Am. Chem. Soc., 106, 811-813.
10. Boutin, J.A., Hennig, P., Lambert, P.-H., Bertin, S., Petit, L., Mahieu, J.-P., Serkiz, B., Volland, J.-P. et al. (1996) Anal. Biochem., 234, 126-141.
11. Braunschweiler, L. and Ernst, R.R. (1983) J. Magn. Reson., 53, 521-528.
12. Brereton, I.M., Crozier, S., Field, J. and Doddrell, D.M. (1991) J. Magn. Reson., 93, 54-62.
13. Burum, D.P. and Ernst, R.R. (1980) J. Magn. Reson., 39, 163-168.
14. Byeon, I.J., Yan, H., Edison, A.S., Booberry, E.S., Abildgaard, F. and Markley, J.L. (1993) Biochemistry, 32, 2508-2521.
15. Cavanagh, J., Fairbrother, W.J., Palmer III, A.G. and Skelton, N.J. (1996) Protein NMR Spectroscopy. Principles and Practice, Academic Press, San Diego, CA, U.S.A.
16. Craik, D.J. and Higgins, K.A. (1989) Annu. Rep. NMR Spectrosc., 22, 61-138.
17. Ernst, R.R. (1966) Adv. Magn. Reson., 2, 1-135.
18. Ernst, R.R., Bodenhausen, G. and Wokaun, A. (1987) Principles of Nuclear Magnetic Resonances in One and Two Dimensions, Oxford Science Publications, Oxford.
19. Fesik, S.W. and Zuiderweg, E.R.P. (1988) J. Magn. Reson., 78, 588-593.
20. Grzesiek, S. and Bax, A. (1993) J. Am. Chem. Soc., 115, 12593-12594.
21. Jeener, J. (1971) Ampère International Summer School, Basko Polje, proposal.
22. Jeener, J., Meier, B.H., Bachmann, P. and Ernst, R.R. (1979) J. Chem. Phys., 71, 4546-4563.
23. Kay, L.E., Keifer, P. and Saarinen, T. (1992) J. Am. Chem. Soc., 114, 10663-10665.
24. Kontaxis, G., Stonehouse, J., Laue, E.D. and Keeler, J. (1994) J. Magn. Reson., A111, 70-76.
25. Macura, S. and Brown, L.R. (1985) J. Magn. Reson., 62, 328-335.
26. Marion, D. and Wüthrich, K. (1983) Biochem. Biophys. Res. Commun., 113, 967-974.
27. Marion, D., Ikura, M., Tschudin, R. and Bax, A. (1989) J. Magn. Reson., 85, 393-399.
28. Markley, J.L., Horsley, W.J. and Klein, M.P. (1971) J. Chem. Phys., 55, 3604-3605.
29. Morris, G.A. and Freeman, R. (1979) J. Am. Chem. Soc., 101, 760-762.
30. Müller, L. (1979) J. Am. Chem. Soc., 101, 4481-4484.
31. Piotto, M., Saudek, V. and Sklenář, V. (1992) J. Biomol. NMR, 2, 661-665.
32. Rizo, J., Liu, Z.P. and Gierasch, L.M. (1994) J. Biomol. NMR, 4, 741-760.
33. Ross, A., Czisch, M., Cieslar, C. and Holak, T.A. (1993) J. Biomol. NMR, 3, 215-224.
34. Ross, A., Czisch, M. and Holak, T.A. (1996) J. Magn. Reson., A118, 221-226.
35. Shaka, A.J. and Keeler, J. (1987) Prog. Magn. Reson. Spectrosc., 19, 47-129.
36. Shuker, S.B., Hajduk, P.J., Meadows, R.P. and Fesik, S.W. (1996) Science, 274, 1531-1534.
37. States, D.J., Haberkorn, R.A. and Ruben, D.J. (1982) J. Magn. Reson., 48, 286-292.
38. Traficante, D.D. (1992) Conc. Magn. Reson., 4, 153-160.
39. Venters, R.A., Huang, C.C., Farmer II, B.T., Trolard, R., Spicer, L.D. and Fierke, C.A. (1995) J. Biomol. NMR, 5, 339-344.
40. Wang, J.F., Hinke, A.P., Loh, S.N., LeMaster, D.M. and Markley, J.L. (1992) Biochemistry, 31, 921-936.
41. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, Wiley, New York, NY, U.S.A.