Rapid Quantitation of Potato Glycoalkaloids by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Journal of Agricultural and Food Chemistry

Volumn 44, Issue 8, 1996, Pages 2292-2296

  Abell, Darcy C ^a   Sporns, Peter ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Chaconine; MALDI; Solanine; Tomatine

Indexed keywords

SOLANUM TUBEROSUM;

EID: 0001170454     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9507102     Document Type: Article

References (33)

1. Barbour, J. D.; Kennedy, G. G.; Roe, R. M. Development of an enzyme linked immunosorbant assay for the steroidal glycoalkaloid α-tomatine. Rev. Pest. Toxicol. 1991, 1, 289-303.
2. Beavis, R. C. Matrix-assisted ultraviolet laser desorption: evolution and principles. Org. Mass Spectrom. 1992, 27, 653-659.
3. Bushway, R. J.; Bureau, J. L.; King, J. Modification of the rapid high-performance liquid chromatographic method for the determination of potato glycoalkaloids. J. Agric. Food Chem. 1986, 34, 277-279.
4. Bushway, R. J.; Perkins, L. B.; Paradis, L. R.; Vanderpan, S. High-performance liquid chromatographic determination of the tomato glycoalkaloid, tomatine, in green and red tomatoes. J. Agric. Food Chem. 1994, 42, 2824-2829.
5. Coxon, D. T. Methodology for glycoalkaloid analysis. Am. Potato J. 1984, 61, 161-183.
6. Fenselau, C. Analysis of peptide and protein structures by mass spectrometry. In Advances in Mass Spectrometry; Cornides, L., Horvath, G., Vekey, K., Eds.; Wiley: London, 1995.
7. Fewell, A. M.; Roddick, J. G.; Weissenberg, M. Interactive antifungal activity of the glycoalkaloids α-solanine and α-chaconine. Phytochemistry 1993, 33 (2), 323-328.
8. Fewell, A. M.; Roddick, J. G.; Weissenberg, M. Interactions between the glycoalkaloids solasonine and solamargine in relation to inhibition of fungal growth. Phytochemistry 1994, 37 (4), 1007-1011.
9. Friedman, M.; Dao, L. Distribution of glycoalkaloids in potato plants and commercial potato products. J. Agric. Food Chem. 1992, 40, 419-423.
10. Friedman, M.; Levin, C. E.; McDonald, G. M. α-Tomatine determination in tomatoes by HPLC using pulsed amperometric detection. J. Agric. Food Chem. 1994, 42, 1959-1964.
11. Gregory, P.; Sinden, S. L.; Osman, S. F.; Tingey, W. M.; Chessin, D. A. Glycoalkaloids of wild, tuber-bearing Solanum species. J. Agric. Food Chem. 1981, 29, 1212-1215.
12. 3H-solanine in rat and hamster. Xenobiotica 1993, 23 (9), 995-1005.
13. Gusev, A. I.; Wilkinson, W. R.; Proctor, A.; Hercules, D. M. Improvement of signal reproducibility and matrix/comatrix effects in MALDI analysis. Anal. Chem. 1995, 67, 1034-1041.
14. Hall, R. L. Toxicological burdens and the shifting burden on toxicology. Food Technol. 1992, 46 (3), 109-112.
15. Harvey, D. J. Matrix-assisted laser desorption/ionization mass spectrometry of oligosaccharides. Am. Lab. 1994 (Dec), 22-28.
16. Jadhav, S. J.; Sharma, R. P.; Salunkhe, D. K. Naturally occurring toxic alkaloids in foods. CRC Crit. Rev. Toxicol. 1981, 9, 21-104.
17. Juhasz, P.; Costello, C. E. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of underivatized and permethylated gangliosides. Am. Soc. Mass Spectrom. 1992, 3, 85-796.
18. Maga, J. A. Potato glycoalkaloids. Crit. Rev. Food Sci. Nutr. 1980, 12, 371-405.
19. Morgan, M. R. A.; Coxon, D. T. Tolerances: glycoalkaloids in potatoes. In Natural Toxicants in Food: Progress and Prospects; Watson, D. H., Ed.; Ellis Horwood: New York, 1987; pp 221-230.
20. Morgan, M. R. A.; McNerneym, R.; Matthew, J. A.; Coxon, D. T.; Chan, H. W. S. An enzyme-linked immunosorbant assay for total glycoalkaloids in potato tubers. J. Sci. Food Agric. 1983, 34, 593-598.
21. Morris, S. C.; Lee, T. H. The toxicity and teratogenicity of Solanaceae glycoalkaloids, particularly those of the potato (Solanum tuberosum): a review. Food Technol. Aust. 1984, 36, 118-124.
22. Plhak, L. C.; Sporns, P. Enzyme immunoassay for potato glycoalkaloids. J. Agric. Food Chem. 1992, 40, 2533-2540.
23. Plhak, L. C.; Sporns, P. Development and production of monoclonal antibodies for the measurement of solanidine potato glycoalkaloids. Am. Potato J. 1994, 71, 297-313.
24. Rideout, D.; Bustamante, A.; Siuzdak, G. Cationic drug analysis using matrix-assisted laser desorption/ionization mass spectrometry: application to influx kinetics, multidrug resistance, and intracellular chemical change. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 10226-10229.
25. Ross, H.; Pasemann, P.; Nitzche, W. Glycoalkaloid content of potatoes and its relationship to location, year and taste. Z. Pflanzenzuecht. 1978, 80, 64-79.
26. Saito, K.; Horie, M.; Hoshino, Y.; Nose, N. High-performance liquid chromatographic determination of glycoalkaloids in potatoes. J. Chromatogr. 1990, 508, 141-147.
27. Sanford, L. L.; Sinden, S. L. Inheritance of potato glycoalkaloids. Am. Potato J. 1972, 49, 209-217.
28. Siuzdak, G. The emergence of mass spectrometry in biomedical research. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 11290-11297.
29. Slanina, P. Solanine (glycoalkaloids) in potatoes: Toxicological evaluation. Food Chem. Toxicol. 1990, 28, 759-761.
30. Stahl, B.; Steup, M.; Karas, M.; Hillenkamp, F. Analysis of neutral oligosaccharides by matrix-assisted laser desoption/ionization mass spectrometry. Anal. Chem. 1991, 63, 1463-1466.
31. Stanker, L. H.; Kamps-Holtzapple, C.; Friedman, M. Development and characterization of monoclonal antibodies that differentiate between potato and tomato glycoalkaloids and aglycons. J. Agric. Food Chem. 1994, 42, 2360-2366.
32. Thomson, C. A.; Sporns, P. Fluorescence polarization immunoassays for potato glycoalkaloids. J. Agric. Food Chem. 1995, 43, 254-260.
33. van Gelder, W. M. J. Steroidal glycoalkaloids in Solanum: consequences for potato breeding and food safety. In Handbook of Natural Toxins. Toxicology of Plant and Fungal Compounds; Keeler, R. F., Tu, A. T., Eds.; Dekker: New York, 1991; Vol. 6, pp 101-134.