Comparison of Beilstein crossfireplusreactions and the selective reaction databases under ISIS

Journal of Chemical Information and Computer Sciences

Volumn 39, Issue 2, 1999, Pages 281-288

  Parkar, Faiz A ^a   Parkin, Don ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b DARESBURY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001131768     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci980334w     Document Type: Article

References (21)

1. REACCS (REAction ACCess System); MDL Information Systems Inc., San Leandro, CA.
2. SYNLIB (SYNthesis LIBrary); Distributed Chemical Graphics Inc., Philadelphia, PA.
3. ORAC (Organic Reactions Accessed by Computer); MDL Information Systems Inc., San Leandro, CA.
4. Zass, E.; Mueller, S. New Research Opportunities Concerning Organic-Chemical Reactions - A Comparison of the In - House Databank Reaccs, Synlib and Orac Systems. Chimia 1986, 40, 38-50.
5. Borkent, J. H.; Oukes, F.; Noordik, J. H. Chemical Reaction Searching Compared in REACCS, SYNLIB, and ORAC. J. Chem. Inf. Comput. Sci. 1988, 28, 148-150.
6. Boiten, J.-W.; Ott, M. A.; Noordik, J. H., Automated Overlap Analysis of Reaction Databases. J. Chem. Inf. Comput. Sci. 1995, 35, 115-120.
7. Blake, J. E.; Dana, R. C. CASREACT; More than a Million Reactions. J. Chem. Inf. Comput. Sci. 1990, 30, 394-399.
8. Beilstein: Beilstein Informationsysteme GmbH, Frankfurt, Germany. See also: Jochum, C. The Beilstein Information System Is Not a Reaction Database, or Is It? J. Chem. Inf. Comput. Sci. 1994, 34, 71-73.
9. Zass E. Using Beilstein Reaction Database in an Academic Environment. In The Beilstein System. Strategies for Effective Searching; Heller, S. R., Ed.; American Chemical Society: Washington, DC, 1998; p 99.
10. ISIS (Integrated Scientific Information System); MDL Information Systems Inc., San Leandro, CA.
11. CDS (Chemical Database Service). See: The United Kingdom Chemical Database Service. Fletcher, D. A.; McMeeking, R. F.; Parkin, D. J. Chem. Inf. Comput. Sci. 1996, 36, 746-749.
12. CDS (Chemical Database Service). See: The United Kingdom Chemical Database Service. Fletcher, D. A.; McMeeking, R. F.; Parkin, D. J. Chem. Inf. Comput. Sci. 1996, 36, 746-749.
13. MIDAS (Manchester Information Datasets and Associated Data); University of Manchester, Manchester, UK.
14. ISIS searches were obtained via ISIS/Base (version 2.1.1) from the CDS and Beilstein searches via CrossFire (version 3.1, build 13) Commander (version 2.3, build 1) from MIDAS. All searches were conducted during normal working hours (9:00 a.m. to 5:00 p.m.). It should, however, be noted that any times quoted are for the UK academic environment, and times for other environments will vary depending on the quality and load of the server.
15. ISIS references are often written as year, volume, and issue number then page number(s), whereas Beilstein references are usually volume and issue number, year, then page range. However, not only is the format different, but the information may be different, such as different author spelling and page numbers (e.g., ISIS = Gibbs, D. E.; Verkade, J. G. Synth Commun [SYNCAV] 1976, 6, 103. Beilstein = Gibs; Verkade; SYNCAV Synth Commun.; 6; 1976; 103, 104, 106; and 6; 1976; 103, 104, 107) and even page ranges (for example, CIRX = 1997, 27 (4), 691-699; Beilstein = 27; 4; 1997; 691-700). Therefore, literature comparisons were restricted to just journal CODEN, year, and starting page number.
16. 16 and converted to text. Superfluous data were removed by manipulations within Microsoft Word and Excel.
17. Gsview and Ghostscript: GSview is a graphical interface for Ghostscript under MS-Windows or OS/2. Ghostscript is an interpreter for the PostScript page description language used by laser printers and is owned by Aladdin Enterprises, Menlo Park, CA. For documents following the Adobe PostScript Document Structuring Conventions, GSview allows selected pages to be viewed or printed.
18. CIRX (Cheminform Reaction Databases); FIZ CHEMIE, Berlin.
19. Depends on time of day/number of users (see ref 13).
20. SPG: Protecting Groups Database, Synopsys Scientific Systems Ltd., Headingley, Leeds, LS6 2EN, UK.
21. Solid-Phase Synthesis databases, e.g., SPS from Synopsys Scientific Systems Ltd., Headingley, Leeds, LS6 2EN, UK, or SPORE (Solid-Phase Organic REactions) developed jointly by MDL Information Systems Inc., San Leandro, CA, and FIZ CHEMIE, Berlin.