Porphyrin-Anthraquinone hybrids: Wavelength dependent DNA photonucleases

Tetrahedron Letters

Volumn 38, Issue 40, 1997, Pages 7125-7128

  Mehta, Goverdhan ^a   Muthusamy, Sengodagounder ^a   Maiya, Bhaskar G ^a   Arounaguiri, S ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAQUINONE DERIVATIVE; PHOTOSENSITIZING AGENT; PORPHYRIN DERIVATIVE;

ARTICLE; DNA DEGRADATION; ENZYME ACTIVITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTOCHEMISTRY; SPECTROPHOTOMETRY;

EID: 0001101556     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01637-7     Document Type: Article

References (14)

1. Morgan, A. R. Curr. Med. Chem., 1995, 2, 604.
2. (b) Bonnett, R., Chem. Soc. Rev. 1995, 19.
3. (c) Photodynamic Therapy: Basic Principles and Clinical Applications', Henderson, R. W.; Dougherty, T. J., Eds.; Marcel Dekker: New York, 1992.
4. Zhou, C. J. Photochem. Photobiol. B:Biol. 1989, 3, 299. (and references therein)
5. Mehta, G.; Sambaiah, T.; Maiya, B. G.; Sirish, M.; Chatterjea, D. J. Chem. Soc. Perkin Trans. 1. 1993, 2667.
6. (b) Mehta, G.; Sambaiah, T.; Maiya, B. G.; Sirish, M.; Dattagupta, A. J. Chem. Soc. Perkin Trans. 1. 1995, 295.
7. (c) Mehta, G.; Muthusamy, S.; Maiya, B. G.; Sirish, M., J. Chem. Soc. Perkin Trans. 1. 1996, 2421.
8. Milder, S. J.; Ding, L.; Etemad-Moghadam, G.; Meunier, B.; Paillous, N. J. Chem. Soc. Chem. Commun. 1990, 1131.
9. (b) Sentagne, C.; Meunier, B.; Paillous, N. J. Photochem. Photobiol B: Biol. 1992, 16, 47.
10. Mehta, G.; Sambaiah, T.; Maiya, B. G.; Sirish, M.; Dattagupta, A. Tetrahedron. Lett. 1994, 35, 4201.
11. Breslin, D. T.; Coury, J. E.; Anderson, J. R.; Mcfail-Isom, L.; Kan, Y.; Williams, L. D.; Bottomley, L. A.; Schuster, G. B. J. Am. Chem. Soc. 1997, 119, 5043 (and references therein).
12. Wasielewski, M. R. Chem. Rev. 1992, 92, 435.
13. 3): δ -2.81 (2H, br s), 2.72 (9H, s), 4.60 (2H, t), 4.92 (2H, t), 7.33 (2H, d), 7.57 (6H, d), 7.73 (2H, m), 8.12 (6H, d), 8.18 (4H, m), 8.38 (2H, m), 8.87 (8H, s), 8.96 (1H, s).
14. There is <5% competitive absorption by the other chromophore at each of these wavelengths.