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Volumn 1, Issue 1, 1991, Pages 104-113

Structure and function of restriction endonucleases. Current Opinion in Structural Biology 1991, 1:104-113

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Indexed keywords


EID: 0001076529     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-440X(91)90018-O     Document Type: Article
Times cited : (156)

References (29)
  • 3
    • 0025280401 scopus 로고
    • Structural Studies of Protein-Nucleic Acid Interaction: The Sources of Sequence-Specific Binding
    • (1990) Q Rev Biophys , vol.23 , pp. 205-280
    • Steitz1
  • 5
    • 0025187081 scopus 로고
    • Refinement of EcoRI Endonuclease Crystal Structure: A Revised Chain Tracing
    • The authors present revised chain tracing of the EcoRI endonuclease protein based on new isomorphous derivative data. The central kink, four-barreled helix motif and overall protein topology previously reported are unchanged, and new features include the extended-chain motif, β-bridge and the placement of Glu111.
    • (1990) Science , vol.249 , pp. 1307-1309
    • Kim1    Grable2    Love3    Greene4    Rosenberg5
  • 8
    • 0022910040 scopus 로고
    • The Effects of Base Analogue Substitutions on the Cleavage by the EcoRI Restriction Endonuclease of Octadeoxyribonucleotides Containing Modified EcoRI Recognition Sequences
    • (1986) J Biol Chem , vol.261 , pp. 7270-7278
    • Brennan1    Van Cleve2    Gumport3
  • 10
    • 0025371752 scopus 로고
    • Substrate Recognition by the EcoRI Endonuclease
    • This paper reports the isolation and characterization of the effects of 50 out of 60 possible mutations at the Glu144, Arg145 and Arg200 loci. Some of the mutants retain partial cleavage activity directed towards the canonical EcoRI site, leading the authors to the conclusion that the pyrimidines are contacted by additional interactions with the protein involving other amino acid residues.
    • (1990) Proteins , vol.7 , pp. 185-197
    • Heitman1    Model2
  • 11
    • 0024379261 scopus 로고
    • Glu-111 is Required for Activation of the DNA Cleavage Center of EcoRI Endonuclease
    • (1989) J Biol Chem , vol.264 , pp. 11807-11815
    • King1    Benkovic2    Modrich3
  • 12
    • 0024359479 scopus 로고
    • The Negative Charge of Glu-111 is Required to Activate the Cleavage Center of EcoRI Endonuclease
    • (1989) J Biol Chem , vol.264 , pp. 11816-11821
    • Wright1    King2    Modrich3
  • 16
    • 0025203657 scopus 로고
    • The Energetic Basis of Sequence Specificity in the Interaction of EcoRI Endonuclease with DNA
    • An exhaustive report on the kinetic and thermodynamic parameters of EcoRI endonuclease binding to, and nicking at, sites containing base analogs and substitutions. Ethylation-interference data demonstrate the existence of the canonical, isosteric and adaptive binding modes.
    • (1990) Science , vol.250 , pp. 776-778
    • Lesser1    Kurpiewski2    Jen-Jacobson3
  • 18
    • 84912861917 scopus 로고    scopus 로고
    • A functional analysis of the effects of these amino acid substitutions. The ED144 mutation changed the mechanistic pathway of the enzyme from one in which double-strand cleavage is the primary result of a single binding event to one in which the enzyme rapidly dissociates after nicking the DNA.
  • 21
    • 0025367454 scopus 로고
    • Accuracy of the EcoRI Endonuclease: Binding and Cleavage Studies with Oligodeoxynucleotide Substrates Containing Degenerate Recognition Sequences
    • ∗) and base-pair mismatches within the EcoRI recognition sequence.
    • (1990) Biochemistry , vol.29 , pp. 4682-4691
    • Thielking1    Alves2    Fleiss3    Maass4    Pingoud5
  • 23
    • 0024322164 scopus 로고
    • Discrimination Between DNA Sequences by the EcoRV Restriction Endonuclease
    • 2+ and nicks the DNA in a single binding event. The nicks may be repaired by DNA ligase, which inhibits the nicking in vitro.
    • (1989) Biochemistry , vol.28 , pp. 6198-6207
    • Taylor1    Halford2
  • 25
    • 0025171673 scopus 로고
    • Mutants of the EcoRI Endonuclease with Promiscuous Substrate Specificity implicate Residues Involved in Substrate Recognition
    • (1990) EMBO J
    • Heitman1    Model2
  • 26
    • 84912896058 scopus 로고    scopus 로고
    • ∗ sites in physiological buffers.
  • 29


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.