Abortifacient Activity in Beef Cattle of Acetyl- and Succinylisocupressic Acid from Ponderosa Pine

Journal of Agricultural and Food Chemistry

Volumn 44, Issue 10, 1996, Pages 3257-3261

  Gardner, Dale R ^a   Panter, Kip E ^a   Molyneux, Russell J ^b   James, Lynn F ^a   Stegelmeier, Bryan L ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

Bovine abortion; Pinus ponderosa; Premature partuition; Ruminai ester hydrolysis

Indexed keywords

BOS TAURUS; BOVINAE; PINUS PONDEROSA;

EID: 0001054654     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf960290w     Document Type: Article

References (19)

1. Al-Mahmoud, M. S.; Ford, S. P.; Short, R. E.; Parley, D. B.; Christenson, L.; Rosazza, J. P. N. Isolation and characterization of vasoactive lipids from the needles of Pinus ponderosa. J. Agric. Food Chem. 1995, 43, 2154-2161.
2. 2+ channel activity of caruncular arteries. J. Reprod. Fertil. 1993, 98, 301-306.
3. Ford, S. P.; Christenson, L. K.; Rosazza, J. P.; Short, R. E. Effects of ponderosa pine needle ingestion on uterine vascular function in late-gestation beef cows. J. Anim. Sci. 1992, 70, 1609-1614.
4. Fujii, R.; Zinkel, D. F. Minor components of ponderosa pine oleoresin. Phytochemistry 1984, 23, 875-878.
5. Gardner, D. R.; Molyneux, R. J.; James, L. F.; Panter, K. E.; Stegelmeier, B. L. Ponderosa pine needle-induced abortion in beef cattle: identification of isocupressic acid as the principal active compound. J. Agric. Food Chem. 1994, 42, 756-761.
6. Harris, L. E. Nutrition Research Techniques for Domestic and Wild Animals; AgriServices: Logan, UT, 1967; Vol. 1, p 5001.
7. James, L. F.; Call, J. W.; Stevenson, A. H. Experimentally induced pine needle abortion in range cattle. Cornell Vet. 1977, 67, 294-299.
8. James, L. F.; Short, R. E.; Panter, K. E.; Molyneux, R. J.; Stuart, L. D.; Bellows, R. A. Pine needle abortion in cattle: a review and report of 1973-1984 research. Cornell Vet. 1989, 79, 39-52.
9. James, L. F.; Molyneux, R. J.; Panter, K. E.; Gardner, D. R.; Stegelmeier, B. L. Effect of feeding ponderosa pine needle extracts and their residues to pregnant cattle. Cornell Vet. 1994, 84, 33-39.
10. Lacey, J. R.; James, L. F.; Short, R. E. Ponderosa pine: economic impact. In The Ecology and Economic Impact of Poisonous Plants on Livestock Production; James, Ralphs, Nielsen, Eds.; Westview Press: Boulder, CO, 1988; pp 95-106.
11. MacDonald, J. Macrocarpa poisoning. N. Z. Vet. J. 1956, 4, 30.
12. MacDonald, M. A. Pine needle abortion in range beef cattle. J. Range Manag. 1952, 5, 150-155.
13. Mangoni, L.; Belardini, M. Sui componenti della resina di Cupressus sempervirens. Nota I. Acido communico, acido cupressico e acido isocupressico. Gazz. Chim. Ital. 1964, 94, 1108-1121.
14. Miner, J. L.; Bellows, R. A.; Staigmiller, R. B.; Peterson, M. K.; Short, R. E.; James, L. F. Montana pine needles cause abortion in beef cattle. Montana Ag Research; Montana Ag. Exp. Sta., Montana State Univ.: Bozeman, 1987; p 4, 6-9.
15. Panter, K. E.; James, L. F.; Molyneux, R. J.; Short, R. E.; Sisson, D. V. Premature bovine parturition induced by ponderosa pine: effects of pine needles, bark and branch tips. Cornell Vet. 1990, 80, 329-338.
16. Parton, K.; Gardner, D.; Williamson, N. B. Isocupressic acid, an abortifacient component of Cupressus macrocarpa. N. Z. Vet. J. 1996, 44, 109-111.
17. Sloss, V.; Brady, J. W. Abnormal births in cattle following ingestion of Cupressus macrocarpa foliage. Aust. Vet. J. 1983, 60, 223.
18. Tilley, J. M. A.; Terry, R. A. A two-state technique for the in vitro digestion of forage crops. J. Br. Grass. Soc. 1963, 18, 104-111.
19. Zinkel, D. F.; Magee, T. V. Resin acids of Pinus ponderosa needles. Phytochemistry 1991, 30, 845-848.