Determination of benzodiazepines in human urine and plasma with solvent modified solid phase micro extraction and gas chromatography; rationalisation of method development using experimental design strategies

Journal of Pharmaceutical and Biomedical Analysis

Volumn 18, Issue 4-5, 1998, Pages 667-680

  Reubsaet, Karianne Johansen ^a   Norli, Hans Ragnar ^b   Hemmersbach, Peter ^b   Rasmussen, Knut E ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b AKER UNIVERSITY HOSPITAL   (Norway)

Author keywords

Benzodiazepines; Chromatography; Octanol; SPME

Indexed keywords

ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; FLUNITRAZEPAM; NORDAZEPAM; OXAZEPAM;

ACCURACY; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG URINE LEVEL; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; TECHNIQUE; URINALYSIS;

ALPRAZOLAM; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; CHROMATOGRAPHY, GAS; DIAZEPAM; FLUNITRAZEPAM; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; NORDAZEPAM; OXAZEPAM; RESEARCH DESIGN;

EID: 0001041259     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(98)00275-1     Document Type: Article

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