HYCRON, an Allylic Anchor for High-Efficiency Solid Phase Synthesis of Protected Peptides and Glycopeptides

Journal of Organic Chemistry

Volumn 62, Issue 4, 1997, Pages 813-826

  Seitz, Oliver ^a   Kunz, Horst ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001035088     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo960743w     Document Type: Article

References (67)

1. Abbreviations: AA, amino acid; Ac, acetyl; Acm, acetamidomethyl; Bn, benzyl; Boc, tert-butyloxycarbonyl; DCC, N,N '-dicyclohexylcarbodiimide; DIC, N,N '-diisopropylcarbodiimide; DIPEA, diisopropylethylamine; DKP, diketopiperazine; EtSMe, ethyl methyl sulfide; Fmoc, 9-fluorenylmethoxycarbonyl; Gal, D-galactopyranose; GalNAc, 2-acetamido-2-deoxy-D-galactopyranose; Glc, D-Glucopyranose; GPC, gel permeation chromatography; HOBt, 1-hydroxybenzotriazole; HONSu, N-hydroxysuccinimide; HYCRAM, hrydroxycrotonoyl (aminomethyl)polystyrene; HYCRON, hydroxycrotyl-oligoethylene glycol-n-alkanoyl; MPLC, medium performance liquid chromatography; Mtr, 4-methoxy-2,3,6-trimethylbenzenesulfonyl; Muc, mucine; NMM, N-methylmorpholine; Pac, phenacyl; PS, polystyrene; tBu, tert-butyl; Trt, trityl; TBTU, 2-O-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; Z, Benzyloxycarbonyl.
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