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85034473834
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After complete conversion of carbodiimide, the reaction mixture was concentrated and the residue was separated by preparative silica gel TLC using pentane/ether as the developer.
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0001638084
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-1 for the minor products).
-
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44
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85034462843
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note
-
The product ratios of the 7 to 8 of the reaction (entry 5), by using tricyclohexylphosphine, dppp, and dppb were 1.6:1,1-1 and 0.8: 1, respectively.
-
-
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45
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85034470299
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We thank one of the referees for this suggestion
-
We thank one of the referees for this suggestion.
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46
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0011404010
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TolBINAP = 2,2′-bis(di-p-tolylphosphino)-1,1′-binaphthyl. See: Takaya, H.; Mashima, K.; Koyano, K.; Yagi, M.; Kumobayashi, H.; Taketomi, T.; Akutagawa, S.; Noyori, R. J. Org. Chem, 1986, 51, 629.
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47
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85034484929
-
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note
-
Enantiomers of regioisomers 8 could not be separated up to acceptable standard by using Chiracel OD column.
-
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48
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0000276556
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