Clonazepam release from core-shell type nanoparticles in vitro

Archives of Pharmacal Research

Volumn 20, Issue 4, 1997, Pages 324-329

  Kim, Hyun Jung ^a   Jeong, Young Il ^a   Kim, Sung Ho ^b   Lee, Young Moo ^c   Cho, Chong Su ^a  

^a Chonnam National University   (South Korea)

^b Chosun University   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

Amphiphilic copolymers; Core shell type nanoparticle; Critical micelle concentration; Diafiltration method

Indexed keywords

EID: 0001012269     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02976194     Document Type: Article

References (22)

1. Allemann, E., Gurny, R. and Doelker, E., Drug-loaded nanoparticles-preparation methods and drug targeting issues. Eur. J. Pharm. Biopharm., 39, 173-191 (1993).
2. Kreuter, J., Nanoparticle-based drug delivery systems. J. Control. Rel., 16, 169-176 (1991).
3. Porter, C. J. H., Moghimi, S. M., Illum, L. and Davis, S. S., The polyoxtethylene/polyoxyprophylene block copolymer poloxamer-407 selectivity redirects intravenously injected microsperes to sinusoidal endothelial cells of rabbit bone marrow. FEBS Let., 305, 62-66 (1992).
4. Couvreur, P., Fattal, E., Alphandary, H., Puisieux, F. and Andremont, A., Intracellular targeting of antibiotics by means of biodegradable nanoparticles. J. Contr. Rel., 19, 259-268 (1992).
5. Kwon, G. S., Naito, M., Yokoyama, M., okano, T., Sakurai, Y. and Kataoka, K., Physical entrapment of adriamycin in AB block copolymer micelles. Pharm. Res., 12, 192-195 (1995).
6. Hashida, M. and Takakura, Y., Phamacokinetics in design of polymeric drug delivery systems. J. Control. Rel., 31, 163-171 (1995).
7. Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V., Torchilin, V. and Langer, R., Biodegradable long-circulating polymeric nanospheres. Science, 263, 1600-1603 (1994).
8. Yokoyama, Y., Kwon, G. S., Okano, Y., Sakurai, Y. and Kataoka, K., Micelle-Forming Polymeric Drug, Chap. 10, American chemical society, 131-133 (1994).
9. Kuroyanagi, Y., Kim, E. and Shioya, N., Evaluation of a synthetic wound dressing capable of releasing silver sulfadiazine. J. Burn Care & Rehabilitation, 12, 106-121 (1991).
10. Edward, W., Merrill and Edwin, W., Polyethylene oxide as a biomaterial. Am. Soc. Art. Int. Org., 6, 60-64 (1983).
11. Jeon, S. I., Lee, J. H., Andrade, J. D. and De, Gennes, P. G., Protein-surface interactions in the presence of polyethylene oxide. J. Colloid. Interface Sci., 142, 149-166 (1991)
12. Verrecchia, T., Spenlehauer, G., Bazile, D. V., Murry-Brelier, A., Archimbaud, Y. and Veillard, M., Non-stealth(poly(lactic acid/albumin)) and stealth(poly (lactic acid-polyethylene glycol)) nanoparticles as injectable drug carriers. J. Control. Rel., 36, 49-61 (1995).
13. Courtney, J. M., Lamba, N. M. K., Sundaram, S. and Forbes, C. D., Biomarteials for blood-contacting applications. Biomaterials, 15, 737-744 (1994).
14. Cho, C. S., Kim, S. W. and Komoto, T., Synthesis and structural study of an ABA block copolymer consisting of poly(γ-benzyl L-glutamate) as the A block and poly(ethylene oxide) as the B block. Macromol. Chem., 191, 981-991 (1990).
15. Cho, C. S., Jo, B. W., Kwon, J. K. and Komoto, T., Synthesis and structural study of an ABA block copolymer consisting of poly(ε-benzyloxycarbonyl L-lysine) as the A block and poly(ethylene oxide) as the B block. Macromol. Chem. Phys., 195, 2195-2206 (1994).
16. Lasic, D. D., Mixed micelles in drug delivery. Nature, 355, 279-280 (1992).
17. Goodman, M. and Hutchison, J., The mechanisms of polymerization of N-unsubstituted N-carboxyanhydride. J. Am. Chem. Soc., 88, 3627-3630 (1966).
18. Cho, C. S., Na, J. W., Jeong, Y. I., Kim, S. H., Lee, Y. M., and Sung, Y. K., Micelle formation of the hexablock copolymer consisting of poly poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part. Polymer (Korea), 19, 926-931 (1995).
19. Wilhelm, M., Zhao, C. L., Wang, Y., Xu, R., Winnik, M. A., Mura, J. L., Riess, G. and Croucher, M. D., Poly(styrene-ethylene oxide) block copolymer micelle formation in water:A fluorescence probe study. Macromolecules, 124, 1033-1040 (1991).
20. Marctic, P. A. and Nair, M., Microenviroment sensing of block copolymer micelles by fluorescence spectroscopy. J. Colloids Interface Sci., 163, 517-519 (1994).
21. Vagberg, L. J. M., Cogan, K. A. and Gast, A. P., Light-scattering study of starlike polymeric micelles. Macromolecules, 24, 1670-1677 (1991).
22. Xu, R., Winnik, M. A., Hallett, F. R., Riess, G. and Croucher, M. O., Light-scattering study of the association behavior of styrene-ethylene oxide block copolymers in aqueous solution. Macromolecules, 24, 87-93 (1991).