Liquid Chromatographic Determination of Chlorothiazide and Hydrochlorothiazide Diuretic Drugs in Bovine Milk

Journal of Agricultural and Food Chemistry

Volumn 46, Issue 3, 1998, Pages 1039-1043

  Shaikh, Badar ^a   Rummel, Nathan ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Bovine milk; Chlorothiazide; Diuretics; Hydrochlorothiazide; Incurred residue; LC; Thiazides; Trichlormethiazide

Indexed keywords

BOVINAE;

EID: 0001010668     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf970637a     Document Type: Article

References (10)

1. Campins-Falco, P., et al. Solid-Phase Extraction Techniques for Assay of Diuretics in Human Urine Samples. J. Liq. Chromatogr. 1991, 14, 3575-3590.
2. Center for Veterinary Medicine/FDA. General Principals for Evaluating the Safety of Compounds Used in Food Producing Animals: Guidelines for Approval of a Method of Analysis for Residues; FDA: Rockville, MD, Sept 1986.
3. Code of Federal Regulations. Food and Drugs, Parts 520.420 and 522.1150; U.S. GPO: Washington, DC, 1991.
4. Cooper, S. F., et al. Comprehensive Screening Procedure for Diuretics in Urine by High-Performance Liquid Chromatography. J. Chromatogr. 1989, 489, 65-88.
5. Herraez-Hernandez, R., et al. Estimation of Diuretic Drugs in Biological Fluids by HPLC. Chromatographia 1992, 33, 177-185.
6. Shaikh, B. Development and Validation of a Liquid Chromatographic Method for the Determination of Furosemide, a Diuretic, in Bovine Milk. J. Agric. Food Chem. 1996, 43, 2117-2121.
7. Shaikh, B. Diuretic Drugs Used in Food Producing Animals. In Veterinary Drug Residues; ACS Symposium Series 636; Moats, W. A., Medina, M. B., Eds.; American Chemical Society: Washington, DC, 1996; pp 161-168.
8. Shaikh, B.; Rummel, N. Determination of Trichlormethiazide in Bovine Milk by High Performance Liquid Chromatography. J. Chromatogr. B., Biomed. Sci. Appl. 1997, in press.
9. Veterinary Pharmaceuticals and Biologicals, 8th ed.; Veterinary Medicine Publishing: Lenexa, KS, 1993/1994; pp 729-730.
10. Werthmann, Jr., M. W.; Krees, S. V. J. Extraction of Chlorothiazide in Human Breast Milk. Pediatrics 1972, 81, 781-783.