Post-transcriptional transgene silencing and consequent tospovirus resistance in transgenic lettuce are affected by transgene dosage and plant development

Plant Journal

Volumn 9, Issue 6, 1996, Pages 899-909

  Pang, Sheng Zhi ^a   Jan, Fuh Jyh ^a   Carney, Kim ^b   Stout, John ^b   Tricoli, David M ^b   Quemada, Hector D ^b   Gonsalves, Dennis ^a  

^a New York State Agricultural Experiment Station   (United States)

^b Asgrow Seed Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTUCA; LYCOPERSICON ESCULENTUM; TOMATO SPOTTED WILT VIRUS; TOSPOVIRUS;

EID: 0001008857     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-313X.1996.9060899.x     Document Type: Article

References (55)

1. An, G. (1986) Development of plant promoter expression vectors and their use for analysis of differential activity of nopaline synthase promoter in transformed tobacco cells. Plant Physiol. 81, 86-91.
2. Assaad, F.F., Tucker, K.L. and Signer, E.R. (1993) Epigenetic repeatinduced gene silencing (RIGS) in Arabidopsis. Plant Mol. Biol. 22, 1067-1085.
3. Beachy, R.N. (1993) Transgenic resistance to plant viruses. Semin. Virot. 4, 327-416.
4. Beachy, R.N., Loesch-Fries, S. and Turner, N.E. (1990) Coat proteinmediated resistance against virus infection. Ann. Rev. Phytopathol. 28, 451-474.
5. Boerjan, W., Bauw, G., van Montagu, M. and Inze, D. (1994) Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco. Plant Cell, 6, 1401-1414.
6. de Carvalho, F., Gheysen, G., Kushnir, S., van Montagu, M., Inze, D. and Castresana, C. (1992) Suppression of β-1,3-glucanase transgene expression in homozygous plants. EMBO J. 11, 2595-2602.
7. de Carvalho, F., Frendo, P., Montagu, M.V. and Cornelissen, M. (1995) Post-transcriptional cosupprossion of β-1,3-glucanase genes does not affect accumulation of transgene nuclear mRNA. Plant Cell, 7, 347-358.
8. Cho, J.J., Mau, R.F.L., German, T.L., Hartman, R.W., Yudin, L.S., Gonsalves, D. and Provvidenti, R. (1989) A multidisciplinary approach to management of tomato spotted wilt virus in Hawaii. Plant Dis. 73, 375-383.
9. Dehio, C. and Schell, J. (1994) Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing. Proc. Natl Acad. Sci. USA, 91, 5538-5542.
10. Doyle, J.J. and Doyle, J.L. (1990) Isolation of plant DNA from fresh tissue, Focus, 12, 13-15.
11. Finnegan, J. and McElroy, D. (1994) Transgene inactivation: Plants fight back! Bio/Technology, 12, 883-888.
12. Flavell, R.B. (1994) Inactivation of gene expression in plants as a consequence of specific sequence duplication. Proc. Natl Acad. Sci. USA, 91, 3490-3496.
13. Francki, R.I.B., Fauquet, C.M., Knudson, D.L and Brown, F. (1991) Classification and nomenclature of viruses. 5th Rep. Int. Comm. Tax. Viruses. Arch. Virol. Suppl. 2, 281-283.
14. German, T.L., Ullman, D.E. and Moyer, J.W. (1992) Tospoviruses: diagnosis, molecular biology, phylogeny, and vector relationships. Ann. Rev. Phytopathol. 30, 315-348.
15. Gonsalves, D. and Trujillo, E.E. (1986) Tomato spotted wilt virus in papaya and detection of the virus by ELISA. Plant Dis. 70, 501-506.
16. Grierson, D., Fray, R.G., Hamilton, A.J., Smith, C.J.S. and Watson, C.F. (1991) Does co-suppression of sense genes in transgenic plants involve antisense RNA? Trends Biotechnol. 9, 122-123.
17. Grumet, R. (1994) Development of virus resistant plants via genetic engineering. Plant Breeding Rev. 12, 47-79.
18. de Haan, P., Gielen, J.J.L., Prins, M., Wijkamp, I.G., van Schepen, A., Peters, D., van Grinsven, M.Q.J.M. and Goldbach, R. (1992) Characterization of RNA-mediated resistance to tomato spotted wilt virus in transgenic tobacco plants. Bio/Technology, 10, 1133-1137.
19. Hart, C.M., Fischer, B., Neuhaus, J.-M. and Meins, Jr, F. (1992) Regulated inactivation of homologous gene expression in transgenic Nicotiana sylvestris plants containing a defenserelated tobacco chitinase gene. Mol. Gen. Genet. 235, 179-188.
20. Hobbs, S.L.A., Kpodar, P. and Delong, C.M.O. (1990) The effect of T-DNA copy number, position and methylation on reporter gene expression in tobacco transformants. Plant Mol. Biol. 15, 851-864.
21. Hobbs, S.L.A., Warkentin, T.D. and Delong, C.M.O. (1993) Transgene copy number can be positively or negatively associated with transgene expression. Plant Mol. Biol. 21, 17-26.
22. Hull, R. and Davies, J.W. (1992) Approaches to nonconventional control of plant virus diseases. Crit. Rev. Plant Sci. 11, 17-33.
23. Ingelbrecht, I., van Houdt, H., Montagu, M.V. and Depicker, A. (1994) Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proc. Natl Acad. Sci. USA, 91, 10 502-10 506.
24. Jorgensen, R. (1992) Silencing of plant genes by homologous transgenes. Agbiotechnol. News Info. 4, 265-273.
25. Jorgensen, R. (1993) The germinal inheritance of epigenetic information in plants. Phil. Trans. R. Soc. Lond. (Biol). 339, 173-181.
26. van der Krol, A.R., Mur, L.A., Beld, M., Mol, J.N.M. and Stuitje, A.R. (1990) Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell, 2, 291-299.
27. Lindbo, J.A. and Dougherty, W.G. (1992a) Pathogen-derived resistance to a potyvirus: Immune and resistant phenotypes in transgenic tobacco expressing altered forms of a potyvirus coat protein nucleotide sequence. Mol. Plant-Microbe Interact. 5, 144-153.
28. Lindbo, J.A. and Dougherty, W.G. (1992b) Untranslatable transcripts of the tobacco etch virus coat protein gene sequence can interfere with tobacco etch virus replication in transgenic plants and protoplasts. Virology, 189, 725-733.
29. Lindbo, J.A., Silva-Rosales, L., Proebsting, W.M. and Dougherty, W.G. (1993) Induction of a highly specific antiviral state in transgenic plants: implications for regulation of gene expression and virus resistance. Plant Cell, 5, 1749-1759.
30. Linn, F., Heidmann, I., Saedler, H. and Meyer, P. (1990) Epigenetic changes in the expression of the maize A1 gene in Petunia hybrida: Role of numbers of integrated gene copies and state of methylation. Mol. Gen. Genet. 222, 329-336.
31. Matzke, M.A. and Matzke, A.J.M. (1991) Differential inactivation and methylation of a transgene in plants by two suppressor loci containing homologous sequences. Plant Mol. Biol. 16, 821-830.
32. Matzke, M.A., Primig, M., Trnovsky, J. and Matzke, A.J.M. (1989) Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J. 8, 643-649.
33. Meins, Jr, F. (1989) Habituation: Heritable variation in the requirement of cultured plant cells for hormones. Ann. Rev. Genet. 23, 395-408.
34. Meyer, P., Heidmann, I. and Niedenhof, I. (1993) Differences in DNA-methylation are associated with a paramutation phenomenon in transgenic petunia. Plant J. 4, 89-100.
35. Michelmore, R., Marsh, E., Seely, S. and Landry, B. (1987) Transformation of lettuce (Lactuca sativa) mediated by Agrobacterium tumefaciens. Plant Cell Rep. 6, 439-442.
36. Mol, J., van Blokland. R. and Kooter, J, (1991) More about cosuppression. Trends Biotechnol. 9, 182-183.
37. Mueller, E., Gilbert, J., Davenport, G., Brrigneti, G. and Baulcombe, D.C. (1995) Homology-dependent resistance: transgenic virus resistance in plants related to homology-dependent gene silencing. Plant J. 7, 1001-1013.
38. Napoli, C., Lemieux, C. and Jorgensen, R. (1990) Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell, 2, 279-289.
39. Neuhaus, J.-M., Ahl-Goy, P., Hinz, U., Flores, S. and Meins, F. (1991) High-level expression of a tobacco chitinase gene in Nicotiana sylvestris. Susceptibility of transgenic plants to Cercospora nicotianae infection. Plant Mol. Biol. 16, 141-151.
40. Neuhuber, F., Park, Y.-D., Matzke, A.J.M. and Matzke, M.A. (1994) Susceptibility of transgene loci to homology-dependent gene silencing. Mol. Gen. Genet. 244, 230-241.
41. Pang, S.-Z., Nagpala, P., Wang, M., Slightom, J.L. and Gonsalves, D. (1992) Resistance to heterologous isolates of tomato spotted wilt virus in transgenic tobacco expressing its nucleocapsid protein gene. Phytopathology, 82, 1223-1229.
42. Pang, S.-Z., Slightom, J.L. and Gonsalves, D. (1993) Different mechanisms protect transgenic tobacco against tomato spotted wilt and impatiens necrotic spot tospoviruses. Bio/Technology, 11, 819-824.
43. Pang, S.-Z., Block, J.H., Gonsalves, C., Slightom, J.L. and Gonsalves, D. (1994) Resistance of transgenic Nicotiana benthamiana plants to tomato spotted wilt and impatiens necrotic spot tospoviruses: Evidence of involvement of the N protein and N gene RNA in resistance. Phytopathology, 84, 243-249.
44. Reimann-Philipp, U. and Beachy, R.N. (1993) The mechanism(s) of coat protein-mediated resistance against tobacco mosaic virus. Semin. Virol. 4, 349-356.
45. Sanford, J.C. and Johnston, S.A. (1985) The concept of parasitederived resistance-deriving resistance genes from the parasite's own genome. J. Theor. Biol. 113, 395-405.
46. Scheid, O.M., Paszkowski, J. and Potrykus, I. (1991) Reversible inactivation of a transgene in Arabidopsis thaliana. Mol. Gen. Genet. 228, 104-112.
47. Seymour, G.B., Fray, R.G., Hill, P. and Tucker, G.A. (1993) Downregulation of two non-homologous endogenous tomato genes with a single chimeric sense gene construct. Plant Mol. Biol. 23, 1-9.
48. Slightom, J.L. (1991) Custom polymerase-chain-reaction engineering of a plant expression vector. Gene, 100, 251-255.
49. Smith, C.J.S., Watson, C.F., Bird, C.R., Ray, J., Schuch, W. and Grierson, D. (1990) Expression of a truncated tomato polygalacturonase gene inhibits expression of the endogenous gene in transgenic plants. Mol. Gen. Genet. 224, 477-481.
50. Smith, H.A., Swaney, S.L., Parks, T.D., Wernsman, E.A. and Dougherty, W.G. (1994) Transgenic plant virus resistance mediated by untranslatable sense RNAs: Expression, regulation, and fate of nonessential RNAs. Plant Cell, 6, 1441-1453.
51. Vaucheret, H., Palauqui, J.-C., Elmayan, T. and Moffatt, B. (1995) Molecular and genetic analysis of nitrite reductase co suppression in transgenic tobacco plants. Mol. Gen. Genet. 248, 311-317.
52. N in tobacco plants transformed with the viral coat protein cistron. Plant Mol. Biol. 20, 631-639.
53. Wang, M. and Gonsalves, D. (1990) ELISA detection of various tomato spotted wilt virus isolates using specific antisera to structural proteins of the virus. Plant Dis. 74, 154-158
54. Watterson, J.C. (1993) Development and breeding of resistance to pepper and tomato viruses. In Resistance to Viral Diseases of Vegetables: Genetics and Breeding (Kyle, M.M., ed.). Portland, Oregon: Timber Press, Inc.
55. Wilson, T.M.A. (1993) Strategies to protect crop plants against viruses: Pathogen-derived resistance blossoms. Proc. Natl Acad. Sci. USA, 90, 3134-3141.