Iron ligand mutants in protein R2 of Escherichia coli ribonucleotide reductase: Retention of diiron site, tyrosyl radical and enzymatic activity in mutant proteins lacking an iron-binding side chain

Journal of Biological Inorganic Chemistry

Volumn 1, Issue 3, 1996, Pages 247-256

  Persson, Bert Ove ^a   Karlsson, Margareta ^a   Climent, Isabel ^a   Ling, Jinshu ^b,c   Loehr, Joann Sanders ^b   Sahlin, Margareta ^a   Sjöberg, Britt Marie ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000966031     PISSN: 09498257     EISSN: 14321327     Source Type: Journal    
DOI: 10.1007/s007750050050     Document Type: Article

References (54)

1. Sjöberg B-M (1995) In: Eckstein F, Lilley DMJ (eds) Nucleic acids and molecular biology, vol 9. Springer, Heidelberg, Berlin, New York, pp 192-221
2. Reichard P (1993) Science 260 :1773-1777
3. Stubbe J (1990) Adv Enzymol Relat Areas Mol Biol 63: 349-419
4. Nordlund P, Sjöberg B-M, Eklund H (1990) Nature 345: 593-598
5. Nordlund P, Eklund H (1993) J Mol Biol 232: 123-164
6. Uhlin U, Eklund H (1994) Nature 370 :533-539
7. Sjöberg B-M (1994) Structure 2 :793-796
8. Fox BG, Shanklin J, Ai JY, Loehr TM, Sanders-Loehr J (1994) Biochemistry 33 : 12776-12786
9. Andersson KK, Gräslund A (1995) Adv Inorg Chem 43: 359-408
10. Larsson Å, Sjöberg BM (1986) EMBO J 5:2037-2040
11. Sahlin M, Lassmann G, Pötsch S, Sjöberg BM, Gräslund A (1995) J Biol Chem 270 :12361-12372
12. Ling JS, Sahlin M, Sjöberg B-M, Loehr TM, Sanders-Loehr J (1994) J Biol Chem 269 :5595-5601
13. Ravi N, Bollinger JM, Huynh BH, Edmondson DE, Stubbe J (1994) J Am Chem Soc 116: 8007-8014
14. Bollinger JM, Tong WH, Ravi N, Huynh BH, Edmondson DE, Stubbe J (1994) J Am Chem Soc 116: 8015-8023
15. Bollinger JM, Tong WH, Ravi N, Huynh BH, Edmondson DE, Stubbe J (1994) J Am Chem Soc 116: 8024-8032
16. Tabor S, Richardson CC (1985) Proc Natl Acad Sci USA 82:1074-1078
17. Taylor JW, Ott J, Eckstein F (1985) Nucleic Acids Res 13:8765-8785
18. Sayers JR, Schmidt W, Eckstein F (1988) Nucleic Acids Res 16:791-802
19. Kunkel TA, Roberts JD, Zakour RA (1987) Methods Enzymol 154:367-382
20. Kunkel TA (1985) Proc Natl Acad Sci USA 82: 488-492
21. Green PJ, Betlach MC, Goodman HM, Boyer HW (1974) Methods Mol Biol 7:87-111
22. Sjöberg BM, Hahne S, Karlsson M, Jörnvall H, Göransson M, Uhlin BE (1986) J Biol Chem 261:5658-5662
23. Atkin CL, Thelander L, Reichard P, Lang G (1973) J Biol Chem 248:7464-7472
24. Sahlin M, Sjöberg B-M, Backes G, Loehr T, Sanders-Loehr J (1990) Biochem Biophys Res Commun 167: 813-818
25. Sahlin M, Petersson L, Gräslund A, Ehrenberg A, Sjöberg BM, Thelander L (1987) Biochemistry 26: 5541-5548
26. Thelander L, Sjöberg BM, Eriksson S (1978) Methods Enzymol 51:227-237
27. Loehr TM, Sanders-Loehr J (1993) In: Riordan JF, Valle BL (eds) Metallobiochemistry, part C, vol 226. Academic Press, San Diego, pp 431-470
28. Petersson L, Gräslund A, Ehrenberg A, Sjöberg B-M, Reichard P (1980) J Biol Chem 255: 6706-6712
29. Sanders-Loehr J, Wheeler WD, Shiemke AK, Averill BA, Loehr TM (1989) J Am Chem Soc 111: 8084-8093
30. Backes G, Sahlin M, Sjöberg BM, Loehr TM, Sanders-Loehr J (1989) Biochemistry 28 :1923-1929
31. Shiemke AK, Loehr TM, Sanders-Loehr J (1986) J Am Chem Soc 108 :2437-2443
32. Ehrenberg A, Reichard P (1972) J Biol Chem 247: 3485-3488
33. Matzanake BF, Müller-Matzanake G, Raymond KN (1989) In: Loehr TM (ed) Iron carriers and iron proteins, vol 5. VCH, New York, pp 1-121
34. Gerez C, Gaillard J, Latour J-M, Fontecave M (1991) Angew Chem Int Ed Engl 30:1135-1136
35. Hendrich MP, Elgren TE, Que L Jr (1991) Biochem Biophys Res Commun 176:705-710
36. Davydov R, Kuprin S, Gräslund A, Ehrenberg A (1994) J Am Chem Soc 116:11120-11128
37. Sjöberg BM, Reichard P, Gräslund A, Ehrenberg A (1978) J Biol Chem 253: 6863-6865
38. Jordan A, Pontis E, Atta M, Krook M, Gibert I, Barbe J, Reichard P (1994) Proc Natl Acad Sci USA 91: 12892-12896
39. Barry BA, El-Deeb MK, Sandusky PO, Babcock GT (1990) J Biol Chem 265: 20139-20143
40. Åberg A (1993) PhD thesis, Stockholm University
41. Åberg A, Nordlund P, Eklund H (1993) Nature 361: 276-278
42. Atta M, Nordlund P, Åberg A, Eklund H, Fontecave M (1992) J Biol Chem 267 :20682-20688
43. Åberg A, Ormö M, Nordlund P, Sjöberg BM (1993) Biochemistry 32 :9845-9850
44. Regnström K, Åberg A, Ormö M, Sahlin M, Sjöberg B-M (1994) J Biol Chem 269 :6355-6361
45. Ormö M, deMaré F, Regnström K, Åberg A, Sahlin M, Ling J, Loehr TM, Sanders-Loehr J, Sjöberg BM (1992) J Biol Chem 267:8711-8714
46. Larsson Å, Climent I, Nordlund P, Sahlin M, Sjöberg B-M (1996) Eur J Biochem (in press)
47. Ochiai E, Mann GJ, Gräslund A, Thelander L (1990) J Biol Chem 265:15758-15761
48. Ingemarson R, Gräslund A, Darling A, Thelander L (1989) J Virol 63 : 3769-3776
49. Nielsen BB, Kauppi B, Thelander M, Thelander L, Larsen IK, Eklund H (1995) FEBS Lett 373 :310-312
50. Rova U, Goodtzova K, Ingemarson R, Behravan G, Gräslund A, Thelander L (1995) Biochemistry 34 :4267-4275
51. Åberg A, Hahne S, Karlsson M, Larsson A, Ormö M, Åhgren A, Sjöberg B-M (1989) J Biol Chem 264: 12249-12252
52. Mao SS, Yu GX, Chalfoun D, Stubbe J (1992) Biochemistry 31:9752-9759
53. Climent I, Sjöberg B-M, Huang CY (1992) Biochemistry 31:4801-4807
54. Lynch JB, Juarez-Garcia C, Münck E, Que L Jr (1989) J Biol Chem 264:8091-8096