Effectiveness of P2AM (PAM - Pralidoxime) in the treatment of organophosphorus poisoning (OPP) a randomized, double blind placebo controlled clinical trial

Journal of Association of Physicians of India

Volumn 45, Issue 1, 1997, Pages 22-24

  Cherian, A M ^b   Peter, J V ^b   Samuel, Johnson ^b   Jaydevan, Rajeev ^b   Peter, Shajan ^b   Joel, S ^a   Jeyasselan, L ^b   Thomas, K ^b  

^a Clinical Epidemiology Unit

^b Departinent of Biostatistics ^*

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000961648     PISSN: 00045772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Namba T, Hiraki K. PAM therapy for alkyl-phosphate poisoning. JAMA 1985; 166 : 1834-36.
2. Namba T. Cholinesterase Inhibition by Organophosphorus Compounds and its clinical effects. Bull WHO 1971; 44 : 289-307.
3. Durham WF, Wayland JH. Organic Phosphorus Poisoning and its therapy. Archives of Environmental Health 1962; 5 : 27-47.
4. Namba T, Nolte CT, Jackrel J, Grob D. Poisoning due to organophosphate insecticides. Am J Med 1971; 50 : 475-92.
5. Sanderson DM. Treatment of poisoning by anticholinesterase insecticides in the rat. J Pharm Pharmacol 1961; 13 : 435.
6. De Silva HJ, Wijewickrema R, Senanayake N, et al. Does pralidoxime affect outcome of management in acute organophosphorus poisoning. Lancet 1992; 339 : 1136-38.
7. Johnson MK, Vale JA, Marrs TC, Meredith TJ. Pralidoxime for organophosphorus poisoning. Lancet 1992; 340 : 64.
8. Samuel J, Thomas K, Jeyaseelan L, Peter JV, Cherian AM. Incidence of intermediate syndrome in organophosphorus poisoning. JAPI 1995; 43 : 321-23.
9. Samuel J, Peter JV, Thomas K, Jeyaseelan L, Seshadri MS, Cherian AM. Evaluation of two treatment regimens of Pralidoxime (I gm single bolus does vs 12 gm infusion) in the management of organophosphorus poisoning - a randomised double blind controlled clinical trial - sent for Publication to JAPI.