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85033142930
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The ratio of the diastereoisomers was determined by HPLC using a Shim-Pack CLC-SIL(M) column (hexane - 2-propanol 100:1)
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The ratio of the diastereoisomers was determined by HPLC using a Shim-Pack CLC-SIL(M) column (hexane - 2-propanol 100:1).
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49
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85033146410
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note
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Recrystallization of the diastereomeric mixture of 10 from hexane-EtOAc gave the major diastereomer 10a (>98% de) in 41% yield. The author has deposited atomic coordinates for 10a with the Cambridge Crystallographic Data Centre. The coordinates can be obtained, on request, from the Director, Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB2 IEZ, UK.
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55
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85033127117
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The optical purities of the enantiomers were determined by HPLC using a Chiralcel OD column (hexane-EtOH 100:0.2)
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The optical purities of the enantiomers were determined by HPLC using a Chiralcel OD column (hexane-EtOH 100:0.2).
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