Gender and transcriptional regulation of NO synthase and ET-1 in porcine aortic endothelial cells

American Journal of Physiology

Volumn 273, Issue 4 PART 2, 1997, Pages

  Wang, Xiaofang ^a   Barber, Dustan A ^a   Lewis, Debraa ^a   McGregor, Christopher G A ^a   Sieck, Gary C ^a   Fitzpatrick, Lorraine A ^a   Miller, Virginia M ^a  

^a MAYO CLINIC   (United States)

Author keywords

Endothelin 1; Estrogen; Female; Male; Mrna; Nitric oxide synthase; Sex steroid hormone

Indexed keywords

EID: 0000902154     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.4.h1962     Document Type: Article

References (28)

1. Braman, R. S., and S. A. Hendrix. Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium(III) reduction with chemiluminescence detection. Anal. Chem. 61: 2715-2718,1989.
2. Ernster, V. L., T. L. Bush, G. R. Huggins, B. S. Hullka, J. L. Kelsey, and D. Schottenfeld. Benefits and risks of menopausal estrogen and/or progestin hormone use. Prev. Med. 17: 201-223, 1988.
3. Flier, J. S., and L. H. Underbill. Platelet-endothelium interactions. JV. Engl. J. Med. 328: 628-635,1993.
4. Forstermann, U., E. I. Closs, J. S. Pollock, M. Nakane, P. Schwarz, I. Garth, and H. Kleinert. Nitric oxide synthase isozymes characterization, purification, molecular cloning, and function. Hypertension 23: 1121-1131,1994.
5. Gross, S. S., and R. Levi. Tetrahydrobiopterin synthesis: an absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J. Biol. Chem. 267: 2572225729,1992.
6. Hashimoto, M., M. Akishita, M. Eto, M. Ishikawa, K. Kozaki, K. Toba, Y. Sagara, Y. Taketani, H. Orimo, and Y. Ouchi. Modulation of endothelium-dependent flow-mediated dilatation of the brachial artery by sex and menstrual cycle. Circulation 92: 3431-3435,1995.
7. Hayashi, T., J. M. Fukuto, L. J. Ignarro, and G. Chaudhuri. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc. Natl. Acad. Sei. USA 89:11259-11263,1992.
8. Hayashi, T., K. Yamada, T. Esaki, M. Kuzuya, S. Satake, T. Ishikawa, H. Hidaka, and A. Iguchi. Estrogen increases endothelial nitric oxide by a receptor-mediated system. Biochem. Biophys. Res. Commun. 214: 847-855,1995.
9. Kharitonov, S. A., R. B. Logan-Sinclair, C. M. Busselt, and E. A. Shinebourne. Peak expiratory nitric oxide differences in men and women: relation to the menstrual cycle. Er. Heart J. 72: 243-245,1994.
10. Lerman, A., B. S. Edwards, J. W. Hallett, D. M. Heublein, S. M. Sandberg, and J. C. Burnett, Jr. Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N. Engl. J. Med. 325: 997-1001,1991.
11. Lobo, R. A. The role of progestins in hormone replacement therapy. Am. J. Obstet. Gynecol. 166:1997-2004,1992.
12. Margulies, K. B., F. L. Hildebrand, Jr., A. Lerman, M. A. Perrella, and J. C. Burnett, Jr. Increased endothelin in experimental heart failure. Circulation 82: 2226-2230,1990.
13. Marsden, P. A., K. T. Schappert, H. S. Chen, M. Flowers, C. L. Sundell, J. N. Wilcox, S. Lamas, and T. Michel. Molecular cloning and characterization of human endothelial nitric oxide synthase. FEES Lett. 307: 287-293,1992.
14. Menon, N. K., A. Wolf, M. Zehetgruber, and R. J. Bing. An improved chemiluminescence assay suggests non nitric oxidemediated action of lysophosphatidylcholine and acetylcholine. Soc. Exp. Biol. Med. 37: 316-319,1989.
15. Miller, V. M., and J. C. Burnett, Jr. Modulation of nitric oxide and endothelin by chronic increases in blood flow in canine femoral arteries. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H103-H108,1992.
16. Mulsch, A., and R. Busse. Nitric oxide synthase in native and cultured endothelial cells: calcium/calmodulin and tetrahydrobiopterin are cofactors. J. Cardiovasc. Pharmacol. 17: S52-S56, 1991.
17. Myatt, L., D. E. Brockman, G. Langsdon, and J. S. Pollock. Constitutive calcium-dependent isoform of nitric oxide synthase in the human placental villous vascular tree. Placenta 14: 373-383,1993.
18. Nabulsi, A. A., A. R. Folsom, A. White, W. Patsch, G. Heiss, K. K. Wu, and M. Szklo. Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. The atherosclerosis risk in communities study investigators. N. Engl. J. Med. 328:1069-1075,1993.
19. Notelovitz, M. Estrogen replacement therapy: indications, contradictions, and agent selection. Am. J. Obstet. Gynecol. 161: 1832-1841,1989.
20. Polderman, K. H., C. D. A. Stehouwer, G. J. van Kamp, G. A. Dekker, F. W. A. Verbeugt, and L. J. G. Gooren. Influence of sex hormones on plasma endothelin levels. Ann. Intern. Med. 118: 429-432,1993.
21. Pollock, J. S., V. Klinghofer, U. Forstermann, and F. Murad. Endothelial nitric oxide synthase is myristylated. FEBS Lett. 309:402-404,1992.
22. Rosselli, M., E. Imthurm, E. Macas, P. J. Keller, and R. K. Dubey. Circulating nitrite/nitrate levels increase with follicular development: indirect evidence for estrogen mediated NO release. Biochem. Biophys. Res. Commun. 202:1543-1552,1994.
23. Shichiri, M., Y. Hirata, T. Nakajima, K. Ando, T. Imai, M. Yanagisawa, T. Masaki, and F. Marumo. Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines. J. Clin. Invest. 87:1867-1871,1991.
24. Stampfer, M. J., W. C. Willet, G. A. Colditz, B. Rosner, F. E. Spiezer, and C. H. Hennekens. A prospective study of postmenopausal estrogen therapy and coronary heart disease. N. Engl. J. Med. 313: 1044-1049,1985.
25. Van Buren, G. A., D. S. Yang, and K. E. Clark. Estrogeninduced uterine vasodilatation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis. Am. J. Obstet. Gynecol. 167: 828-833,1992.
26. Wagner, O. F., G. Christ, J. Wojta, H. Vierhapper, S. Parzer, P. J. Nowotny, B. Schneider, W. Waldhausl, and B. R. Binder. Polar secretion of endothelin-1 by cultured endothelial cells. J. Biol. Chem. 267:16066-16068, 1992.
27. Weiner, C. P., R. G. Knowles, and S. Moncada. Induction of nitric oxide synthases early in pregnancy. Am. J. Obstet. Gynecol. 171: 838-843,1994.
28. Weiner, C. P., I. Lizasoain, S. A. Baylis, R. G. Knowles, I. G. Charles, and S. Moncada. Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc. Nail. Acad. Sei. USA 91: 5212-5216,1994.