High throughput, mechanism-based screening techniques for discovering novel agrochemicals

Journal of Biomolecular Screening

Volumn 3, Issue 3, 1998, Pages 175-181

  Walsh, James C ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000877218     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/108705719800300303     Document Type: Article

References (6)

1. Walsh, J.C. (1992). Use of robotics for high throughput natural products screening. Presented at the Proceedings of the International Symposium on Laboratory Automation and Robotics, 1992, p. 592.
2. Kirsch, D.R. Lai, M. (1986). A modified screen for the detection of cell wall-acting antifungal compounds. J. Antibiotics 39:1620.
3. Ozenberger, B., Young, K. (1995). Functional interaction of ligands and receptors of the hematopoietic superfamily in yeast. Mol. Endocrinol. 9:1321.
4. Fields, S., Song, O. (1989). A novel genetic system to detect protein-protein interactions. Nature 340:245.
5. Chien, C., Bartel, P.L., Stemglanz, R., Fields, S. (1991). The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA. 88:9578.
6. Leanna, C.A., Hannink, M. (1996). The reverse two-hybrid system: A genetic scheme for selection against specific protein/protein interactions. Nucleic Acids Res. 24:3341.