Sample sizes for the Transmission Disequilibrium Tests: TDT, S-TDT and 1-TDT

Communications in Statistics - Theory and Methods

Volumn 29, Issue 5-6, 2000, Pages 1129-1142

  Wang, Dai ^a   Sun, Fengzhu ^a,b  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Association; Gene; Linkage disequilibrium; Power

Indexed keywords

EID: 0000866217     PISSN: 03610926     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Boehnke, M. and Langefeld, C. D.(1998). "Genetic association mapping based on discordant sib pairs: The discordant-alleles test", Am. J. Hum. Genet. 62, 950-961.
2. Camp, N. J.(1997). "Genomewide transmission/disequilibrium testing: Consideration of the genotypic relative risks at disease loci", Am. J. Hum. Genet. 61, 1424-1430.
3. Chimowitz, M. I., Kokkinos, J., Strong, J., Brown, M. B., Levine, S. R., Silliman, S., Pessin, M. S., Weichel, E., Sila, C. A., Furlan, A. J., Kargman, D. E., Sacco, R. L., Wityk, R. J., Ford, G. and Fayad, P. B.(1995). "The Warfarin-Aspirin symptomatic intracranial disease study", Neurology 45, 1488-1493.
4. Curtis, D.(1997). "Use of siblings as controls in case-control association studies", Ann. Hum. Genet. 61, 319-333.
5. Ewens, W. J. and Spielman, R. S.(1995). "The transmission disequilibrium test: History, subdivision and admixture", Am. J. Hum. Genet. 57, 455-464.
6. Horvath, S. and Laird, N. M.(1998). "A discordant-sibship test for disequilibrium and linkage: No need for parental data", Am. J. Hum. Genet. 63, 1886-1897.
7. Knapp, M.(1999a). "A note on power approximations for the transmission/disequilibrium test", Am. J. Hum. Genet. 64, 1177-1185.
8. Knapp, M.(1999b). "The transmission/disequilibrium test and parental-genotype reconstruction: The reconstruction-combined transmission/disequilibrium test", Am. J. Hum. Genet. 64, 861-870.
9. Monks, S. A., Kaplan, N. L and Weir, B. S.(1998). "A comparative study of sibship tests of linkage and/or association" Am. J. Hum. Genet. 63, 1507-1516.
10. Rao, C. R.(1973). Linear statistical inference and its applications, 2nd ed. John Wiley, New York.
11. Risch, N. and Merikangas, K.(1996). "The future of genetic studies of complex human diseases", Science 273, 1516-1517.
12. Risch, N. and Teng, J.(1998). "The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling", Genome Res. 8, 1273-1288.
13. Shaw, S. H., Carrasquillo, M. M., Kashuk, C., Puffenberger, E. G. and Chakravarti, A.(1998). "Allele frequency distributions in pooled DNA samples: Applications to mapping complex disease genes", Genome Res. 8, 111-123.
14. Spielman, R. S., McGinnis, R. E. and Ewens, W. J.(1993). "Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)", Am. J. Hum. Genet. 52, 506-516.
15. Spielman, R. S. and Ewens, W. J.(1998). "A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test", Am. J. Hum. Genet. 62, 450-458.
16. Sun, F. Z., Flanders, W. D., Yang, Q. H. and Khoury, M. J.(1998). "A new method for estimating the risk ratio in studies using case-parental control design", Am. J. Epidemiol. 148, 902-909.
17. Sun, F. Z., Flanders, W. D., Yang, Q. H. and Khoury, M. J.(1999). "The transmission disequilibrium test (TDT) when only one parent is available: the 1-TDT", Am. J. Epidemiol. 150, 97-104.
18. Tu, I-Ping and Whittemore, A. S.(1999). "Power of association and linkage tests when the disease alleles are unobserved", Am. J. Hum. Genet. 64, 641-649.
19. Weinberg, C. R.(1999). "Allowing for missing parents in genetic studies of case-parent traids", Am. J. Hum. Genet. 64, 1186-1193.