Osteopontin: Potential roles in vascular function and dystrophic calcification

Journal of Bone and Mineral Metabolism

Volumn 15, Issue 4, 1997, Pages 179-183

  Giachelli, Cecilia M ^a   Scatena, Marta ^a   Wada, Takeo ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000862760     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02491379     Document Type: Article

References (50)

1. Giachelli CM, Schwartz SM, Liaw L (1995) Molecular and cellular biology of osteopontin: potential role in cardiovascular disease. Trends Cardiovasc Med 5:88-95
2. Denhardt D, Guo X (1993) Osteopontin: a protein with diverse functions. FASEB J 7 1475-1482
3. Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM (1994) Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 74:214-224
4. Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Scwartz SM, Giachelli CM (1995) The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of avb3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest 95:713-724
5. Nasu K, Ishida T, Setoguchi M, Higuchi Y, Akizuki S, Yamamoto S (1995) Expression of wild-type and mutated rabbit osteopontin in Escherichia coli and their effects on adhesion and migration of P388D1 cells. Biochem J 307:257-265
6. Weintraub AS, Gichelli CM, Krauss RS, Almeida M, Taubman M (1996) Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their invasion into collagen gels. Am J Pathol 149:259-272
7. Weber GF, Ashkar S, Glimcher ML, Cantor H (1996) Receptor-ligand interaction between CD44 and osteopontin (eta-1). Science 271:509-512
8. Smith LL, Ling LE, Cheung HK, Chen, Sheppard DS, Pytela R, Giachelli CM (1996) Osteopontin N-termianl domain contains a cryptic adhesive sequence recognized by a9b1 integrin. J Biol Chem 271:28485-28491
9. Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM (1993) Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest 92:1686-1696
10. O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, Giachelli CM (1994) Osteopontin is synthesized by macrophages, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 14:1648-1656
11. Reidy MA, Fingerle J, Majesky MW (1988) Proliferation of vascular smooth muscle cells in vivo. In: Suckling KE, Groot PHE (eds) Hyperlipidaemia and atherosclerosis. Academic London, pp 149-164
12. Giachelli CM, Bae N, Lomdardi DM, Majesky MW, Schwartz SM (1991) Molecular cloning and characterization of 2B7. a rat mRNA which distinguishes smooth muscle cell phenotypes in vitro and is identical to osteopontin (secreted phosphoprotein I. 2aR). Biochem Biophys Res Commun 177:867-873
13. Liaw L, Linder V, Schwartz SM, Chambers AF, Giachelli CM (1995) Oteopontin and b3 integrin arc coordinately expressed in regenerating endothelium in vivo and stimulate arg-gly-asp-dependent endothelial migration in vitro. Circ Res 77:665-672
14. Choi ET, Engel L, Callow AD, Sun S, Trachtenberg J, Santoro S, Ryan US (1994) Inhibition of neointimal hyperplasia by blocking avb3 integrin with small peptide antagonist GpenGRGDSPCA. J Vasc Surg 19:124-134
15. Liaw L, Lombardi DM, Almeida MM, Schwartz, deBlois D, Giachelli CM. Neutralizing antibodies directed against osteopontin inhibit rat carotid neointimal thickening following endothelial denudation. Arterioscler Thromb Vasc Biol 17:188-193
16. Scatena M, Nicosia RF, Almeida M, Giachelli CM (1997) Osteopontin promoters endothelial cell survival. Microcirculation 4:126. Abs 32
17. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Chresh DA (1996) Definition of two pathways by distinct av integrins. Science 270:1500-1502
18. Brooks PC, Clark RAP, Cheresh DA (1994) Requirement of vascular integrin avb3 for angiogenesis. Science 264:569-572
19. Brooks PC, Montgomery AMP, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA (1994) Integrin avb3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157-1164
20. Senger DR, Ledbetter SR, Claffey KP, Papadopuolus-Sergiou A, Peruzzi CA, Detmar M (1996) Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms invoving the avb3 integrin. osteopontin. and thrombin. Am J Pathol 149:293-304
21. Murry CE, Giachelli CM, Schwartz SM, Vracko R (1994) Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol 145:1450-1462
22. Giachelli CM, Pichler R, Lombardi D, Denhardt DT, Alpers CE, Schwartz SM, Johnson RJ (1994) Osteopontin expression in angiotensin II induced tubulointerstitial nephritis. Kidney Inter 45315-524
23. Blumenthal HT, Lansing AI, Wheeler PA (1944) Calcification of the media of the human aorta and its relationship to intimal arteriosclerosis, aging and disease. Am J Pathol 20:665-687
24. McCarthy J, Palmer F (1974) Incidence and significance of coronary artery calcification. Br Heart J 36:499-506
25. Frink RJ, Achor RWP, Brown JAL, Kincaid OW, Brandenburg RO (1970) Significance of calcification of the coronary arteries. Am J Cardiol 26:241-247
26. Locker TH, Schwartz RS, Cotta CW, Hickman JR (1992) Fluoroscopic coronary artery calcification and associated coronary disease in asymptomatic young men. J Am Coll Cardiol 19:1167-1172
27. Fitzgerald PJ, Ports TA, Yock PG (1992) Contribution of localized calcium deposits to dissection after angioplasty: an observational study using intravascular ultrasound. Circulation 86:64-70
28. Rumberger JA, Schwartz RS, Simons DB, Sheedy PF, Edwards WD, Fitzpatrick LA (1994) Relation of coronary calcium determined by electron beam computed tomography and lumen narrowing determined by autopsy. Am J Cardiol 93:1169-1173
29. Demer LL, Watson KE, Bostrom K (1994) Mechanism of calcification in atherosclerosis. Trends Cardiovasc Med 4:45-49
30. Kim KM (1976) Calcification of matrix vesicles in human aortic valve and aortic media. Fed Proc 35:156-162
31. Tanimura A, McGregor DH, Anderson HC (1986) Calcification in atherosclerosis. I: Human studies. J Exp Pathol 2:261-272
32. Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL (1993) Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 91:1800-1809
33. Keeley FW (1977) The extraction and partial characterization of proteins released by decalcification from calcified human aortic plaques. Biochem Biophys Acta 494:384-394
34. Levy RJ, Howard SL, Oshry LJ (1986) Carboxyglutamic acid (Gla) containing proteins of human calcified atherosclerotic plaque solubilized by EDTA. Atherosclerosis 59:155-160
35. Shanahan CM, Weissberg PL, Metcalfe JC (1993) Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells. Circ Res 73:193-204
36. Shanahan CM, Cary NRB, Metcalfe JC, Weissberg PL (1994) High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest 93:2393-2402
37. Fleet JC, Hock JM (1994) Identification of osteocalcin mRNA in nonosteroid tissue of rats and humans by reverse transcription-polymerase chain reaction. J Bone Miner Res 9:1565-1573
38. O'Brien KD, Kuusisto J, Reichenbach DD, Ferguson M, Giachelli CM, Alpers CE, Otto CM (1995) Osteopontin is expressed in human aortic valvular lesions: evidence that aortic valve calcification may be actively regulated. Circulation 92:2163-2168
39. Ikeda T, Shirasawa T, Esaki Y, Yoshiki S, Hirokawa K (1993) Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 92:2814-2820
40. Hirota S, Imakita M, Kohri K, Ito A, Morii E, Adachi S, Kim H-M, Kitamura Y, Yutani C, Nomura S (1993) Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques: a possible association with calcification. Am J Pathol 143:1003-1008
41. Fitzpatrick LA, Severson A, Edwards WD, Ingram RT (1994) Diffuse calcification in human coronary arteries: association of osteopontin with atherosclerosis. J Clin Invest 94:1597-1604
42. Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL (1994) TGF-b1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 93:2106-2113
43. Shioi A, Nishizawa Y, Jono S, Koyama H, Hosoi M, Morii H (1995) β-Glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 15:2003-2009
44. Butler WT (1989) The nature and significance of osteopontin. Connect Tissue Res 23:123-136
45. Shiraga H, Min W, VanDusen WJ, Clayman MD, Miner D, Terrell CH, Sherbotie JR, Foreman JW, Przyslecki C, Neilson EG, Hover JR (1992) Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily. Proc Natl Acad Sci USA 89:426-430
46. Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW (1993) Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner 22:147-159
47. Hunter GK, Kyle CL, Goldberg HA (1994) Modulation of crystal formation by bone phosphoproteins: structural specificity of the osteopontin-mediated inhibition of hydroxyapatite formation. Biochem J 300:723-728
48. Hunter GK, Goldberg HA (1993) Nucleation of hydroxyapatite by bone sialoprotein. Proc NatI Acad Sci USA 90:8562-8565
49. Whyte MP (1994) Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocr Rev 15:439-461
50. Fedde KN, Ambroziak B, LaBanca C, Henthron PS, Whyte MP (1994) Alkaline phosphatase modulates phosphorylation of 3 extracellular proteins: a hypophosphatasia fibroblast study (abstr). J Bone Miner Res 9:S184