Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides

Journal of Cell Science

Volumn 112, Issue 1, 1999, Pages 127-135

  Noël, Veerle ^a   Willems, Jean ^b   Vandekerckhove, Joël ^c   Van Frans, Roy ^d   Bruyneel, Erik ^a   Mareel, Marc ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Cadherin fragment; Cell cell adhesion; E cadherin catenin; HAV peptide; Invasion

Indexed keywords

ALANINE; CATENIN; HISTIDINE; UVOMORULIN; VALINE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL AGGREGATION; CELL INVASION; CELL STRAIN; EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; CADHERINS; CELL AGGREGATION; CELL LINE; CELL MOVEMENT; CHICK EMBRYO; COLLAGEN; CRICETINAE; CULTURE MEDIA, CONDITIONED; DOGS; EPITHELIAL CELLS; HISTIDINE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; OLIGOPEPTIDES; VALINE;

ANIMALIA;

EID: 0000836705     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Banks, R. E., Porter, W. H., Whelan, P., Smith, P. H. and Selby, P. J. (1995).. Soluble forms of the adhesion molecule E-cadherin in urine. J. Clin. Pathol. 48, 179-180.
2. Becker, K. F., Atkinson, M. J., Reich, U., Huang, H. H., Nekarda, H., Siewert, J. R. and Höfler, H. (1993). Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas. Hum. Mol. Genet. 2, 803-804.
3. Behrens, J., Mareel, M. M., Van Roy, F. M., and Birchmeier, W. (1989). Dissecting tumor cell invasion: epithelial cells acquire invasive properties following the loss of uvomorulin-mediated cell-cell adhesion. J. Cell Biol. 108, 2435-2447.
4. Behrens, J., Vakaet, L., Friis, R., Winterhager, E., Van Roy, F., Mareel, M. M., and Birchmeier, W. (1993). Loss of epithelial morphotype and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-src gene. J. Cell Biol. 120, 757-766.
5. Berx, G., Cleton-Jansen, A.-M., Strumane, K., de Leeuw, W. J. F., Nollet, F., Van Roy, F. and Cornelisse, C. (1996). E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 13, 1919-1925.
6. Birchmeier, W., Weidner, K. M., Hülsken, J. and Behrens, J. (1993). Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas. Semin. Cancer Biol. 4, 231-239.
7. Blaschuk, O. W., Sullivan, R., David, S. and Pouliot, Y. (1990). Identification of a cadherin cell adhesion recognition sequence. Dev. Biol. 139, 227-229.
8. Bracke, M. E., Vyncke, B. M., Bruyneel, E. A., Vermeulen, S. J., De Bruyne. G. K., Van Larebeke, N. A., Vleminckx, K., Van Roy, F. M. and Mareel., M. M. (1993). Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro. Br. J. Cancer 68, 282-289.
9. Bracke, M. E. and Mareel, M. M. (1994). Invasion assay using embryonic chick heart. In Cell & Tissue Culture: Laboratory Procedures, vol 5A:4 (ed. A. Doyle. J. B. Griffiths and D. G. Newell), pp. 1-16. John Wiley & Sons. Chicester.
10. Breviario, F., Caveda, L., Corada, M., Martin-Padura, I., Navarro, P., Golay, J., Introna, M., Gulino, D., Lampugnani, M. G. and Dejana, E. (1995). Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. Arterioscler. Thromb. Vasc. Biol. 15, 1229-1239.
11. Brieher, W. M., Yap, A. S. and Gumbiner, B. M. (1996). Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135, 487-496.
12. Byers, S., Amaya, E., Munro, S. and Blaschuk, O. (1992). Fibroblast growth factor receptors contain a conserved HAV region common to cadherins and influenza strain A hemagglutinins: a role in protein-protein interactions? Dev. Biol. 152, 411-414.
13. Chambers, A. F. and Matrisian, L. M. (1997). Changing views of the role of matrix metalloproteinases in metastasis. J. Nat. Cancer Inst. 89, 1260-1270.
14. Frixen, U. H. and Nagamine, Y. (1993). Stimulation of urokinase-type plasminogen activator expression by blockage of E-cadherin-dependent cell-cell adhesion. Cancer Res. 53, 3618-3623.
15. Griffiths, T. R. L., Brotherick, I., Bishop, R. I., White, M. D., McKenna, D. M., D. M. Horne, D. M., Shenton, B. K., Neal, D. E. and Mellon, J. K. (1996). Cell adhesion molecules in bladder cancer: soluble serum E-cadherin correlates with predictors of recurrence. Br. J. Cancer 74, 579-584.
16. Hamaguchi, M., Matsuyoshi, N., Ohnishi, Y., Gotoh, B., Takeichi, M. and Nagai, Y. (1993). p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J. 12, 307-314.
17. Herrenknecht, K. and Kemler, R. (1993). Characterization of recombinant E-cadherin (uvomorulin) expressed in insect cells. J. Cell Sci. Suppl. 17, 147-154.
18. Hinck, L., Näthke, I. S., Papkoff, J. and Nelson, W. J. (1994). Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J. Cell Biol. 125, 1327-1340.
19. Hyafil, F., Morello, D, Babinet, C. and Jacob, F. (1980). A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos. Cell 21, 927-934.
20. Katayama, M., Hirai, S., Kamihagi, K., Nakagawa, K., Yasumoto, M. and Kato, I. (1994). Soluble E-cadherin fragments increased in circulation of cancer patients. Br. J. Cancer 69, 580-585.
21. Koch, A. W., Pokutta, S., Lustig, A. and Engel, J. (1997). Calcium binding and homoassocialion of E-cadherin domains. Biochemistry 36, 7697-7705.
22. Laemmli, V. K. (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227, 680-685.
23. Levi, E., R. Fridman, H.-Q. Miao, Y.-S. Ma, A. Yayon, and I. Vlodavsky, 1996. Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1. Proc. Nat. Acad. Sci. USA 93, 7069-7074.
24. Mareel, M., Kint, J. and Meyvisch, C. (1979). Methods of study of the invasion of malignant C3H mouse fibroblasts into embryonic chick heart in vitro. Virchows Arch. B Cell Pathol. 30, 95-111.
25. Mareel, M., Bracke, M. and Van Roy, F. (1994). Invasion promoter versus invasion suppressor molecules: the paradigm of E-cadherin. Mol. Biol. Rep. 19, 45-67.
26. Matstivoshi, N., Hamaguchi, M., Tanigushi, S., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1992). Cadherin-mediuted cell-cell adhesion is perturbed by r-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118, 703-714.
27. Mbalaviele, G., Chen, H., Boyce, B. F., Mundy, G. R. and Yoneda, T. (1995). The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow. J. Clin. Invest. 95, 2757-2765.
28. Mège, R. M., Matsuzaki, F., Gallin, W. J., Goldberg, J. I., Cunningham, B. A. and Edelman, G. M. (1988). Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proc. Nat. Acad. Sci. USA 85, 7274-7278.
29. Mège, R. M., Goudou, D., Diaz, C., Nicolet, M., Garcia, L., Geraud, G. and Rieger F. (1992). N-cadherin and N-CAM in myoblast fusion: compared localisation and effect of blockade by peptides and antibodies. J. Cell Sci. 103, 897-906.
30. Nagar, B., Overduin, M., Ikura, M. and Rini, J. M. (1996). Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature 380, 360-364.
31. Näthke, I. S., Hinck, L., Swedlow, J. R., Papkoff, J. and Nelson, W. J. (1994). Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol. 125, 1341-1352.
32. Overduin, M., Harvey, T. S., Bagby, S., Tong, K. I., Yau, P., Takeichi, M. and Ikura, M. (1995). Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science 267, 386-389.
33. Pokutta, S., Herrenknecht, K., Kemler, R. and Engel, J. (1994). Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur. J. Biochem. 223, 1019-1026.
34. Shapiro, L., Fannon, A. M., Kwong, P. D., Thompson, A., Lehmann, M. S., Grübel, G., Legrand, J. F., Als-Nielsen, J., Colman, D. R. and Hendrickson, W. A. (1995). Structural basis of cell-cell adhesion by cadherins. Nature 374, 327-337.
35. Stuart, D. (1994). Docking mission accomplished. Nature 371, 19-20.
36. Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
37. Takeichi, M. (1993). Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol. 5, 806-811.
38. Takeichi, M. (1995). Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol. 7, 619-627.
39. Vakaet, L. Jr, V'leminckx, K., Van Roy, F. and Mareel, M. (1991). Numerical evaluation of the invasion of closely related cell lines into collagen type I gels. Invasion Metast. 11, 249-260.
40. Vandenbossche, G. M. R., De Bruyne, G. K., Bruyneel, E. A., Clemminck, G., Vleminckx, K., Van Roy, F. M. and Mareel, M. M. (1994). Microencapsulation of MDCK-ras-e cells prevents loss of the E-cadherin invasion suppressor function in vivo. Int. J. Cancer 57, 73-80.
41. Vermeulen, S. J., Bruyneel, E. A., Van Roy, F. M., Mareel, M. M. and Bracke, M. E. (1995). Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid. Br. J. Cancer 72, 1447-1453.
42. Vleminckx, K., Vakaet, L. Jr, Mareel, M., Fiers, W. and Van Roy, F. (1991).. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66, 107-119.
43. Wheelock, M. J., Buck, C. A., Bechtol, K. B. and Damsky, C. H. (1987). Soluble 80-kd fragment of cell-CAM 120/80 disrupts cell-cell adhesion. J. Cell. Biochem. 34, 187-202.
44. Willems, J., Zwijsen, A., Siegers, H., Nicolaï, S., Bettadapura, J., Raymackers, J. and Scarcez, T. (1993). Purification and sequence of rat extracellular superoxide dismutase B secreted by C6 glioma. J. Biol. Chem. 268, 24614-24621.
45. Willems, J., Bruyneel, E., Noë, V., Slegers, H., Zwijsen, A., Mège, R.-M. and Mareel, M. (1995). Cadherin-dependent cell aggregation is affected by decapeptide derived from rat extracellular super-oxide dismutase. FEBS Lett. 363, 289-292.
46. Williams, E., Furness, J., Walsh, F. S. and Doherty, P. (1994). Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, NCAM and N-cadherin. Neuron 13, 583-594.
47. Zhou, Y., Fisher, S. J., Janatpour, M., Genbacev, O., Dejana, E., Wheelock, M. and Damsky, C. H. (1997). Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J. Clin. Invest. 99, 2139-2151.