A novel coumarin-type derivatizing reagent of alcohols: Application in the CD exciton chirality method for microscale structural determination

Organic Letters

Volumn 2, Issue 5, 2000, Pages 683-685

  Lo, Lee Chiang ^a   Liao, Yuan Chang ^a   Kuo, Chi Hsien ^a   Chen, Chao Tsen ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000728011     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol005514h     Document Type: Article

References (20)

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9. + + 1) calcd 312.1348, found 312.1319.
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11. 7-Diethylaminocoumarin-3-carboxylic acid (2) is a commercially available reagent widely used in the fluorescent labeling of bioconjugates with the surface accessible amino acid side chains. Haugland, R. P. Handbook of Fluorescent Probes and Research Chemicals, 6th ed.; Molecular Probes: Eugene, OR, 1996.
12. 3) δ 162.9, 162.3, 157.5, 152.2, 147.9, 131.0, 110.8, 109.6, 108.4, 96.6, 52.7, 45.0, 32.3, 24.6, 12.4.
13. 3CN solution. After being stirred at rt for 5 h, the mixture was concentrated and the desired product was purified by silica gel column chromatography.
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