Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation

World Journal of Gastroenterology

Volumn 5, Issue 3, 1999, Pages 217-220

  Zhang, Shao Geng ^a   Wu, Meng Chao ^b   Tan, Jing Wang ^a   Chen, Han ^b   Yang, Jia Mei ^b   Qian, Qi Jun ^b  

^a FUZHOU GENERAL HOSPITAL   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Graft rejection; Immunosuppression; Liver transplantation; Perform granzyme B genes

Indexed keywords

EID: 0000721768     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v5.i3.217     Document Type: Article

References (6)

1. Griffiths GM, Mueller C. Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells. Immunol Today, 1991;12:415-419
2. Zhang SG, Tan JW, Yang JM. Three-cuff in hamster to rat orthotopic liver transplantation. J Sec Milit Med Univ, 1998;19:89-90
3. McDiarmid SV, Farmer DG, Kuniyoshi JS. Perforin and granzyme B. Transplant, 1995;59:762-766
4. Valdivia L, Monden M, Gotoh M. Prolonged survival of hamster-to-rat liver xenografts using splenectomy and cyclosporine administration. Transplant, 1987;44:759-763
5. Mueller C, Shao Y, Altermatt HJ. The effect of cyclosporine treatment on the expression of genes encoding granzyme A and perform in the infiltrate of mouse heart transplants. Transplant, 1993;55;139-145
6. Wieder KJ, Hancock WW, Schmidbauer G. Rapamycin treatment depresses intragraft expression of RC/MMP-2, granzyme B and IFN-gamma in rat recipients of cardiac allografts. J Immunol, 1993;151: 1158-166