α,α-Difluoroarylacetic acids: Preparation from (diethylamino)sulfur trifluoride and α-oxoarylacetates

Journal of Organic Chemistry

Volumn 45, Issue 14, 1980, Pages 2883-2887

  Middleton, W J ^a   Bingham, E M ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000711429     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo01302a025     Document Type: Article

References (4)

1. Middleton, W. J. J. Org. Chem. 1975,40, 574; U.S. Patent 3976691, 1976.
2. Yagupol’skii, L. M.; Belinskaya, R. V. Zh. Obshch. Khim. 1958, 28, 772.
3. PCR, Inc., has withdrawn DAST from sale because of explosions they have experienced in its production. See: Cochran, J.; Chem. Eng. News 1979, March 19, p 4. However, we believe DAST is safe to use provided suitable precautions are taken. See: Middleton, W. J. Zh. Obshch. Khim. May 21, p 43.
4. Shaw, K. N. F.; McMillan, A.; Gudmundson, A. G.; Armstrong, M. D. J. Org. Chem. 1958, 23, 1171.