Enzymatic Synthesis of 4-Methylumbelliferyl Glycosides of Trisaccharide and Core Tetrasaccharide, Gal(β1-3)Gal(β1-4)Xyl and GlcA(β1-3)Gal(β1-3)Gal(β-4)Xyl, Corresponding to the Linkage Region of Proteoglycans

Bulletin of the Chemical Society of Japan

Volumn 70, Issue 11, 1997, Pages 2719-2725

  Yasukochi, Takashi ^a   Fukase, Koichi ^a   Suda, Yasuo ^a   Takagaki, Keiichi ^b   Endo, Masahiko ^b   Kusumoto, Shoichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000689585     PISSN: 00092673     EISSN: None     Source Type: Journal    
DOI: 10.1246/bcsj.70.2719     Document Type: Article

References (43)

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34. 4b)
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37. Regioselective acetylation of carbohydrates by the use of lipase: a) W. J. Hennen, H. M. Sweers, Y-F. Wang, and C.-H. Wong, J. Org. Chem., 53, 4939 (1988) b) M. Therisod and A. M. Klivanov, J. Am. Chem. Soc., 108, 5638 (1986) c) H. Waldmann, in "Enzyme Caralysis in Organic Synthesis," ed by K. Drauz and H. Waldmann, VCH, Weinheim (1995), Vol. 2, pp. 868-882.
38. Regioselective acetylation of carbohydrates by the use of lipase: a) W. J. Hennen, H. M. Sweers, Y-F. Wang, and C.-H. Wong, J. Org. Chem., 53, 4939 (1988) b) M. Therisod and A. M. Klivanov, J. Am. Chem. Soc., 108, 5638 (1986) c) H. Waldmann, in "Enzyme Caralysis in Organic Synthesis," ed by K. Drauz and H. Waldmann, VCH, Weinheim (1995), Vol. 2, pp. 868-882.
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42. Unit Definition: One unit of the enzyme hydrolyzes 1.0 μmol of ο-nitrophenyl β-D-galactopyranoside to ο-nitrophenol and D-galactose per min at pH 7.3 and 37°C.
43. Unit difinition: One modified "Fishman" unit of the enzyme liberates 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hour at pH 5.0 and 37°C.