Uric acid: Friend or foe?

Redox Report

Volumn 2, Issue 4, 1996, Pages 231-234

  Benzie, I F F ^a   Strain, J J ^b  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000687128     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1080/13510002.1996.11747055     Document Type: Article

References (19)

1. Ames B N, Cathcart R, Schwiers E, Hochstein P. Uric acid provides an antioxidant defense in humans against oxidant-and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci U S A 1981; 78: 6858-6862.
2. Becker B F. Towards the physiological function of uric acid. Free Radic Biol Med 1993; 14: 615-631.
3. Cutler R C. Antioxidants and aging. Am J Clin Nutr 1991; 53: 373S-379S.
4. Halliwell B. How to characterize a biological antioxidant. Free Radic Res Commun 1990; 9: 1-32.
5. Sevanian A, Davies K J A, Hochstein P. Serum urate as an antioxidant for ascorbic acid. Am J Clin Nutr 1991; 54: 1129S-1134S.
6. Ma Y S, Stone W L, LeClair I O. The effects of vitamin C and urate on the oxidation kinetics of human low-density lipoprotein. Proc Soc Exp Biol Med 1994; 206: 53-59.
7. Wayner D D M, Burton G W, Ingold K U, Barclay L C, Locke S J. The relative contributions of vitamin E, urate, ascorbate and proteins to the total peroxyl radical-trapping antioxidant activity of human blood plasma. Biochim Biophys Acta 1987; 924: 408-419.
8. Benzie I F F. Lipid peroxidation: a review of causes, consequences, measurement and dietary influences. International Journal of Food Science and Nutrition 1996; 47: 233-262.
9. Benzie I F F. Antioxidant vitamins, antioxidant power and lipid peroxidation in plasma: a study of relationships using modified and novel methods of analysis. DPhil Thesis 1996. University of Ulster at Coleraine, UK.
10. Thomas M J. Urate causes the human polymorphonuclear leukocyte to secrete superoxide. Free Radic Biol Med 1992; 12: 89-91.
11. Maples K R, Mason R P. Free radical metabolite of uric acid. J Biol Chem 1988; 263: 1709-1712.
12. Buettner G R. The pecking order of free radicals and antioxidants: lipid peroxidation, alphatocopherol and ascorbate. Arch Biochem Biophys 1993; 300: 535-543.
13. Fessel W J. High uric acid as an indicator of cardiovascular disease. Am J Med 1980; 68: 401-404.
14. Freedman D S, Williamson D F, Gunter E W, Byers T. Relation of serum uric acid to mortality and ischaemic heart disease. The NHANES I Epidemiologic Follow-up Study. Am J Epidemiol 1995; 141: 637-644.
15. Lee J, Sparrow D, Vokonas P S, Landsberg L, Weiss S T. Uric acid and coronary heart disease risk: evidence for a role of uric acid in the obesity-insulin resistance syndrome. Am J Epidemiol 1995; 142: 288-294.
16. Ebenbichler C F, Kirchmair R, Egger C, Patch J R. Postprandial state and atherosclerosis. Curr Opin lipidol 1995; 6: 286-290.
17. Smith R C, Gore J Z, Doyle M P. Degradation of uric acid during autocatalytic oxidation by oxyhaemoglobin induced by sodium nitrite. Free Radic Biol Med 1991; 11: 373-377.
18. Stocker R. Lipoprotein oxidation: mechanistic aspects, methodological aspects and clinical relevance. Curr Opin Lipidol 1994; 5: 422-433.
19. Jackson P, Loughrey C M, Lightbody J H, McNamee P T, Young I S. Effect of haemodialysis on total antioxidant capacity and serum antioxidants in patients with chronic renal failure. Clin Chem 1995; 41: 1135-1138.