Low temperatures stabilize interferon α-2 against proteolysis in Methylophilus methylotrophus and Escherichia coli

Applied Microbiology and Biotechnology

Volumn 31, Issue 2, 1989, Pages 158-162

  Chesshyre, Julian A ^a   Hipkiss, Alan R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000671329     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/BF00262455     Document Type: Article

References (23)

1. Assembly of functional antibodies from immunoglobin heavy and light chains synthesized in E. coli
2. High expression of cloned genes in E. coli and its consequences
3. Proteolysis in the obligate methylotroph Methylophilus methylotrophus
4. Interferon analogues from synthetic genes: an approach to protein structure-activity studies
5. Production of abnormal proteins in Escherichia coli stimulates transcription of lon and other heat shock genes
6. Genetic and physiological modulation of interferon accumulation in Escherichia coli
7. Stabilization of human interferon β synthesis in Escherichia coli by zinc ions
8. Inhibition of breakdown of canavanyl proteins in Escherichia coli by chloramphenicol
9. Degradation of abnormal proteins in Escherichia coli: relative susceptibility of canavanyl proteins and puromycin peptides to proteolysis in vitro
10. Cleavage of structural proteins during assembly of the head protein of bacteriophage T4
11. β-Galactosidase: rates of synthesis and degradation of incomplete proteins
12. Quasireversibility in the unfolding-refolding transition of phosphoglycerate kinase induced by guanine hydrochloride
13. Clear background and highly sensitive protein staining with Coomassie Blue dyes in polyacrylamide gels: a systematic analysis
14. Stability of proteins
15. Formation of soluble recombinant proteins in Escherichia coli is favored by lower growth temperature
16. Multiple joined genes prevent product degradation in Escherichia coli
17. Synthesis and secretion of biologically active interferon-β using a Bacillus subtilis α-amylase secretion vector
18. Stability of urogastrone and some fusion derivatives and their induction of stress proteins in Escherichia coli
19. Escherichia coli contains eight soluble proteolytic activities, one being ATP-dependent
20. Purification of recombinant human IFN α-2
21. Roles of the disulphide bonds in a human alpha interferon
22. The construction of a synthetic Escherichia coli trp promotor and its use in the expression of a synthetic interferon gene