Endotoxins enhance hepatocarcinogenesis induced by oral intake of thioacetamide in rats

World Journal of Gastroenterology

Volumn 4, Issue 1-6, 1998, Pages 128-132

  Yang, Jin Ming ^a   Han, De Wu ^a   Xie, Chun Ming ^c   Liang, Quan Cheng ^b   Zhao, Yuan Chang ^a   Ma, Xue Hui ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^c NONE

Author keywords

Carcinoma, hepatocellular; DNA, neoplasm; Endotoxins; Flow cytometry; Glutamyl transpeptidase metabolism; Liver neoplasms; Rats, Wistar; Thioacetamide

Indexed keywords

EID: 0000657045     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v4.i2.128     Document Type: Article

References (15)

1. Han DW. A study of pathogenic mechanism of hepatic failure - hypothesis of intestinal endotoxemia. Chin J Hepatol, 1995;3(3):46-49
2. Lumsden AB, Henderson JM, Kutner MH. Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood. Hepatology, 1988; 8(2):232-236
3. Niederau C, Fisher R, Sonnenberg A, Stremmel W, Tramprishch HJ, Strohmeyer G. Survival and causes of death in cirrhotic and noncirrhotic patients with primary hemochromatosis. N Engl J Med, 1985;313(4):1256-1262
4. Han DW. Etiology of liver diseases. In: Han DW, ed. Hepatic pathophysiology. Vol 2. Taiyuan: Shanxi United Press of Universities, 1991
5. Mullen KD, McCullough MAJ. Problem with animal models of chronic liver disease: suggestions for improvement in standardization. Hepatology, 1989;9 (2):500-503
6. Noda S, Musumi S, Moriyama M, Yukiko K, Ohta M, Sugano T et al. Population of hepatic macrophages and response of perfused liver to platelet-activating factor during production of Thioacetamide induced cirrhosis in rats. Hepatology, 1996;24(2):412-418
7. Moreira E, Fontana L, Peviago JL, Medina FS, Gil A. Changes in fatty acid composition of plasma, liver microsomes, and erythrocytes in liver cirrhosis induced by oral intake of Thioacetamide in rats. Hepatology, 1995; 21 (1): 199-206
8. Porter WR. TAA-induced hepatic necrosis. J Pharmacol Exp Ther, 1979;208 (1):386
9. Inada K, Endo S, Takahashi K, Suzuki M, Narita T, Yoshida T et al. Establishment of a new perchloric acid treatment method to allow determination of the total endotoxin content in human plasma by the limulus test and clinical application. Microbiol Immunol, 1991;35(4):303-314
10. Xu KC, Meng XY, Wu JW. Diagnostic value of serum γ-glutamyl transferase isoenzyme for hepatocellular carcinoma: a 10-year study. Am J Gastroenterol, 1992;87(8):91
11. Zuo LF, Guo JW, Liu JH. Flow cytometry DNA ploidy analysis in 208 cases of precancerous lesions. Chin J Physic Med, 1992;14(1):31-34
12. Ikuyo T, Rieko N, Shosuke K. Effect of endotoxin on rat liver regeneration after partial hepatectomy. Biochem International, 1992;27(4):1047-1050
13. Dragan YP and Pitot HC. The role of stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat. Carcinogenesis, 1992; 13 (5):379-750
14. Battafarano RJ, Burd RS, Kurrelmeyer KM, Rtaz CA, Dunn DL. Inhibition of splenic macrophage tumor necrosis factorα secretion in vivo by antilipopolysaccharide monoclonal antibodies. Arch Surg, 1994;129(2):179-186
15. Shohachi S, Satoaoshi N, Atsushi S, Takanori S, Hiroyuki K, Hiroyuki M et al. Role of Kupffer cells and the spleen in modulation of endotoxin-induced liver injury after partial hepatectomy. Hepatology, 1996;24(1):219-225