One-pot access to 2,3-disubstituted 1,2,3,4-tetraiiydroquinolines by reductive amination of aldehydes with sodium cyanoborohydride

Heterocycles

Volumn 48, Issue 1, 1998, Pages 171-174

  Lewin, Guy ^a,b   Schaeffer, Corinne ^c  

^a Faculte de Pharmacie   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000650389     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-97-7999     Document Type: Article

References (7)

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4. Y. Nomura, M. Kimura, Y. Takeuchi, and S. Tomoda, Chem. Lett., 1978, 267.
5. O. Doebner, and W. von Miller, Ber., 1884,1 7, 1714.
6. M. Ihara, K. Noguchi, K. Fukumoto, and T. Kametani, Tetrahedron, 1985, 41, 2109.
7. Compared with indole-3-acetaldehyde, N-benzylation increases stability and 2-methylation prevents side reactions at C2.