Pathophysiology of Substrate Utilisation: Importance of Complete Hypoenergetic Nutritional Therapy;Pathophysiologie der Substratverwertung im Streßstoffwechsel: Bedeutung einer vollständigen hypoenergetischen Ernährungstherapie

Aktuelle Ernahrungsmedizin

Volumn 23, Issue 5, 1998, Pages 207-223

  Senftleben, U ^a   Felbinger, T ^a   Suchner, U ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

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EID: 0000601573     PISSN: 03410501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (109)

1. Adibi, S. A.: 76 Metabolism of branched-chain amino acids in altered nutrition. Melabolism 25 (1976) 287-1302
2. Alexander, J. W.: Immunoenhancement via enteral nutrition. Arch. Surg. 128 (1993) 1242-1245
3. Alexander, J. W., S. J. Gonce, P. W. Miskell, M. D. Peck, H. Sax: A new model for studying nutrition in peritonitis. The adverse effect of overfeeding. Ann. Surg. 209 (1989) 334-340
4. Andus, T., T. Geiger, T. Hirano, T. Kishimoto, P. C. Heinrich: Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins. Eur.J. Immunol. 18 (1988) 739-746
5. Askanazi, J., Y. A. Carpentier, D. H. Elwyn, J. Nordenstrom, M. Jeevanandam, S. H. Rosenbaum, F. E. Gump, J. M. Kinney: Influence of total parenteral nutrition on fuel utilization in injury and sepsis. Ann. Surg. 191 (1980) 40-46
6. Askanazi, J., S. H. Rosenbaum, A. I. Hyman, P. A. Silverberg, J. Milic Emili, J. M. Kinney: Respiratory changes induced by the large glucose loads of total parenteral nutrition. JAMA 243 (1980) 1444-1447
7. Bagby, G. J., C. B. Corll, J. J. Thompson, L. A. Wilson: Lipoprotein lipase-suppressing mediator in serum of endotoxin-treated rats. Am. J. Physiol. 251 (1986) E470-E476
8. Bagdade, J. D., R. K. Root, R. J. Bulger: Impaired leukocyte function in patients with poorly controlled diabetes. Diabetes 23 (1974) 9-15
9. Baxter, J. K., T. J. Babineau, C. M. Apovian: Perioperative glucose control predicts increased nosocomial infection in diabetics. Abstr. Crit. Care Med. 18 (1990) S207
10. Behrendt, W., V. Bogatz, G. Giani: The influence of posttraumatic parenteral calorie and nitrogen supply upon the cumulative nitrogen balance. Infusionstherapie 17 (1990) 32-39
11. Benotti, P. G. L. Blackburn: Protein and caloric or macronutrient metabolic management of the critically ill patient. Crit. Care Med. 7 (1979) 520-525
12. Bessey, P. Q.: Nutritional support in critical illness. In: Multiple Organ Failure. E. A. Deitch, editor. Thieme Medical Publishers, Inc. New York (1990) 126-149
13. Black, P. R., D. C. Brooks, P. Q. Bessey, R. R. Wolfe, D. W. Wilmore: Mechanismus of insulin resistance following injury. Ann. Surg. 196, No. 4 (1982) 420-435
14. Bradley, S. F. and C. A. Kauffman: Protein malnutrition and the febrile response in the Fischer rat. J. Leukoc. Biol. 43 (1988) 36-40
15. Burke, J. F., R. R. Wolfe, C. J. Mullany, D. E. Mathews, D. M. Bier: Glucose requirements following burn injury. Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake. Ann. Surg. 190 (1979) 274-285
16. Bursztem. S.: Einfluß der Ernährung auf die Atemarbeit. Anästhesiol. Intensivmed. Notfallmed. Schmerzther. 26 (1991) 326-328
17. Carpentier, Y. A., A. Van Gossum, D. Y. Dubois, R. J. Deckelbaum: Lipid metabolism in parenteral nutrition. In: Clinical nutrition: Parenteral nutrition. J. L. Rombeau and M. D. Caldwell, editors. W. B. Saunders Company, Philadelphia (1993) 35-74
18. Cerra, F. B: Metabolic support. In: Manual ofcritical care. F. B. Cerra, editor. Mosby, St. Louis (1987) 271-325
19. Cerra, F. B.: Hypermetabolism, organ failure, and metabolic support. Surgery 101 (1987) 1-14
20. Cerra, F. B., M. R. Benitez, G. L. Blackburn, R. S. Irwin, K. Jeejeebhoy, D. P. Katz, S. K, Pingleton, J. Pomposelli, J. L. Rombeau, E. Shronts, R. R. Wolfe, G. P. Zaloga: Applied nutrition in ICU patients. A consensus Statement of the American College of Chest Physicians. Chest 111 (1997) 769-778
21. Cerra, F. B., D. Upson, R. Angelico, C. Wiles, J. Lyons, L. Faulkenbach, J. Paysinger. Branched chains support postoperative protein synthesis. Surgery 92 (1982) 192-199
22. Chwals, W. J.: Overfeeding the critically ill child: fact or fantasy? New Horizons 2 (2) (1994) 147-155
23. Cook, J. A., W. C. Wise, D. R. Knapp, and P. V. Halushka: Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. Circ. Shock 8 (1981) 69-76
24. Cuthbertson, D. P.: Post-traumatic metabolism: a multidisciplinary challenge. Surg. Clin. North Am. 58 (1978) 1045-1054
25. Daughaday, W. H., P. Rotwein: Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr. Rev. 10 (1989) 68-91
26. DeBiasse, M. A., D. W. Wilmore: What is optimal nutritional support? New Horizons 2 (2) (1994) 122-130
27. Drabik, M. D., F. C. Schnure, K. T. Mok, L. L. Moldawer, C. A. Dinarello, G. L. Blackburn, B. R. Bistrian: Effect of protein depletion and short-term parenteral refeeding on the host response to interleukin 1 administration. J. Lab. Clin. Med. 109 (1987) 509-516
28. Druml, W.: Sepsis - Pathophysiologie, Stoffwechsel, Therapie. In: Handbuch der Infusionstherapie und klinischen Ernährung. H. P. Schuster and G. Kleinberger, editors. Karger, Basel, München, Paris, London (1985) 182-214
29. Edens, N. K., K. M. Gil, D. H. Elwyn: The effects of varying energy and nitrogen intake on nitrogen balance, body composition, and metabolic rate. Clinics in Chest Medicine 7, No.1 (1986) 3-17
30. Edwards, C. K., R. M. Lorence, D. M. Dunham, S. Arkins, L. M. Yunger, J. A. Greager, R. J. Walter, R. Dantzer, K. W. Kelley: Hypophysectomy inhibits the synthesis of tumor necrosis factor alpha by rat macrophages: partial restoration by exogenous growth hormone or interferon gamma. Endocrinology 128 (1991) 989-986
31. Elwyn, D. H.: Protein metabolism and requirements in the critically ill patient. Crit. Care Clin. 3 (1987) 57-69
32. Elwyn, D. H., F. E. Gump. M. Iles, C. L. Long, J. M. Kinney: Protein and energy of glucose added in hypocaloric amounts to peripherial infusions of ammo acids. Metabolism 27 (1978) 325-331
33. Felig, P.: The glucose-alanine cycle. Metabolism 22 (1973) 179- 207
34. Forse, R. A., R. Leibel, J. Askanazi, J. Hirsch, J. M. Kinney: Adrenergic control of adipocyte lipolysis in trauma and sepsis. Ann. Surg. 206 (1987) 744-75 1
35. Foster, D. W., J. D. McGarry: Endocrine and metabolic adaptation to starvation. In: New aspects of clinical nutrition. G. Kleinbergerand E. Deutsch, editors. Karger, Basel (1983) 240-246
36. Frankel, W. L., N. J. Evans, J. L. Rombeau: Scientific rationale and clinical applikation of parenteral nutrition in critically ill patients. In: Clinical nutrition: Parenteral nutrition. J. L. Rombeau and M. D. Caldwell, editors. W. B. Saunders Company, Philadelphia (1993) 597-616
37. Freund, H. R.: Abnormalities of liver function and hepatic damage associated with total parenteral nutrition. Nutrition 7 (1994) 1-6
38. Fürst, P.: intracellular muscle free amino acids - their measurement and function. Proc. Nutr. Soc. 42 (1983) 451-462
39. Fürst, P. P. Stehle: The potential use of parenteral dipeptides in clinical nutrition. Nutr. Clin. Pract. 8 (1993) 106-111
40. Fürst, P., P. Stehle: Glutaminsupplementierte Ernährung in der klinischen Praxis - Anwendung von glutaminhaltigen Dipeptiden. Infusionsther. Transfusionsmed. 22 (1995) 317-324
41. Fürst, P., P. Stehle: New substrates for protein nutrition. In: Recent advances in clinical nutrition. G. Schlierf, editor. Smith-Gordon, London (1995) 213 ff
42. Gazzangia, A. B., R. H. Bartlett, J. B. Shobe: Nitrogen balance in patients receiving either fat or carbohydrate for total intravenous nutrition. Ann. Surg. 182 (1975) 163-168
43. Georgieff M.: Intravenous feeding-possibilities and limits in the use of glucose and xylitol following trauma and infection, with special reference to liver metabolism. Infusionsther. Klin. Ernähr. 14 (1987) 93-97
44. Georgieff, M., L. L. Moldawer, B. R. Bistrian, G. L. Blackburn: Xylitol, an energy source for intravenous nutrition after Trauma. J. Ent. Patent. Nutr. 9, No.2 (1985) 199-209
45. Giovannini, I., G. Boldrini, M. Castagneto, G. Sganga, G. Nanni, M. Pittiruti, G. Castiglioni: Respiratory quotient and patterns of substrate utilization in human sepsis and trauma. JPEN. J. Parenter. Enteral. Nutr. 7 (1983) 226-230
46. Griffiths, R. D., C. Jones, T. E. A. Palmer: Survival of intensive care patients given glutamine supplemented parenteral nutrition: a double-blind, randomized treatment study. Nutrition 11 (suppl.) (1995) 224-228
47. Grimble, R. F.: Nutritional antioxidants and the modulation of inflammation: Theory and practice. New Horizons 2 (1994) 175-185
48. Hoffman Goetz, L., D. McFarlane, B. R. Bistrian, G. L. Blackburn: Febrile and plasma iron responses of rabbits injected with endogenous pyrogen from malnourished patients. Am. J. Clin. Nutr. 34 (1981) 1109-1116
49. Jahoor, F., M. Desai, D. N. Herndon, R. R. Wolfe: Dynamics of the protein metabolic response to burn injury. Metabolism 37 (1988) 330-337
50. Jeevanandam, M., D. H. Young, W. R. Schiller: Energy cost of fatfuel mobilization in geriatric trauma. Metab. Clin. Exp. 39 (1990) 144-149
51. Jeevanandam, M., D. H. Young, W. R. Schiller: Glucose turnover, oxidation, and indices of recycling in severely traumatized patients. J. Trauma 30 (1990) 582-589
52. Keenan, R. A., L. L. Moldawer, R. D. Yang, I. Kawamura, G. L. Blackburn, B. R. Bistrian: An altered response by peripheral leukocytes to synthesize or release leukocyte endogenous mediator in critically ill, protein-malnourished patients. J. Lab. Clin. Med. 100 (1982) 844-857
53. Kinsella, J. E., B. Lokesh, S. Broughton, J. Whelan: Dietary polyunsaturated fatty acids and eicosanoids: potential effects on the modulation of inflammatory and immune cells: an overview. Nutrition 6, No. 1 (1990) 24-44
54. Kispert, P. M. D. Caldwell: Metabolic changes in sepsis and multiple organ failure. In: Multiple organ failure. E. A. Deitch, editor. Thieme, New York (1990) 104-125
55. Klimberg, V. S. W. W. Souba: The importance of intestinal glutamine metabolism in maintaining a healthy gastrointestinal tract and supporting the body's response to injury and illness. Surg. Annu. 22 (1990) 61-76
56. Lefkowith, J. B.: Essential fatty acid deficiency inhibits the in vivo generation of leukotriene B4 and suppresses levels of resident and elicited leukocytes in acute inflammation. J. Immunol. 140 (1988) 228-233
57. Li, E. J., J. A. Cook, K. M. Spicer, W. C. Wise, J. Rokach, P. V. Halushka: Resistance of essential fatty acid-deficient rats to endotoxin-induced increases in vascular permeability. Circ. Shock 31 (1990) 159-170
58. Liaw, K. Y.: Effect of injury, sepsis, and parenteral nutrition on high-energy phosphates in human liver and muscle. JPEN J. Parenter. Enteral. Nutr. 9 (1985) 28-33
59. Long, C. L and S. F. Lowry: Hormonal regulation of protein metabolism. J. Parent. Ent. Nutr. 14 (6) (1990) 555-562
60. Lowe, D. K., D. O. Jacobs, D. W. Wilmore: Metabolic background. In: Total parenteral nutrition. J. E. Fischer, editor. Little Brown, Boston. Toronto, London (1991) 165 -178
61. Marliss, E. B., T. T. Aoki, R. H. Unger, J. S. Soeldner, G. F. J. Cahill: Glucagon levels and metabolic effects in fasting man. J. Clin. Invest. 49 (1970) 2256-2270
62. Matthews, D. E. Y. Fong: Amino acid and protein metabolism. In: Clinical nutrition: Patenteral nutrition. J. L. Rombeau and M. D. Caldwell, editors. W. B. Saunders Company, Philadelphia (1993) 75-112
63. Odessey, R., E. A. Khairallah, A. L. Goldberg: Origin and possible significance of alanine production by skeletal muscle. J. Biol. Chem. 249 (1974) 7623-7629
64. Overett, T. K., B. R. Bistrian, S. F. Lowry, B. S. Hopkins, D. Miller, and G. L. Blackburn: Total parenteral nutrition in patients with insulin-requiring diabetes mellitus. J. Am. Coll. Nutr. 5 (1986) 79-89
65. Peck, M. D., G. F. Babcock, J. W. Alexander: The role of protein and calorie restriction in outcome from salmonella infection in mice. J. Parent. Ent. Nutr. 16 (1992) 561-565
66. Petersen, S. R., K. A. Kudsk, G. Carpenter, G. E. Sheldon: Malnutrition and immunocompetence: increased mortality following an infectious challenge during hyperalimentation. J. Trauma 21 (1981) 528-533
67. Pomposelli, J. J. B. R. Bistrian: Is total parenteral nutrition immunosuppressive? New Horizons 2 (2) (1994) 224-229
68. Porter, K. A., B. R. Bistrian, G. L. Blackburn: Guidewire catheter exchange with triple culture technique in the management of catheter sepsis. J. Parenter. Enterai. Nutr. 12 (1988) 628-632
69. Schmitz, J. E., W. Schürmann, A. Grünert: Aminosäuren. In: Parenterale Ernährungstherapie. F. W. Ahnefeldt, A. Grünert, and J. E. Schmitz, editors. Springer, Berlin, Heidelberg, New York (1990) 52-72
70. Seidner, D. L., E. A. Mascioli, N. W. Istfan, K. A. Porter, K. Selleck, G. L. Blackburn, B. R. Bistrian: Effects of long-chain triglyceride emulsions on reticuloendothehal system function in humans. J. Parenter. Enteral. Nutr. 13 (1989) 614-619
71. Shamoon, H., R. Hendler, R. S. Sherwin: Synergisric interactions among antiinsulin hormones in the pathogenesis of stress hyperglycemia in humans. J. Clin. Endocrinol. Metab. 52 (1981) 1235-1241
72. Shaw, J. H. R. R. Wolfe: An integrated analysis of glucose, fat, and protein metabolism in severely traumatized patients. Studies in the basal state and the response to total parenteral nutrition. Ann. Surg. 209 (1989) 63-72
73. Sherwin, R. S.: Effect of epinephrine on fuel metabolism in man: role in the response to stress. In: New aspects of clinical nutrition. G. Kleinberger and E. Deutsch, editors. Karger, Basel (1983) 283-305
74. Simmons, P. S., J. M. Miles, I. E. Gerich, M. W. Haymond: Increased proteolysis. An effect of increases in plasma cortisol within the physiologic range. J. Clin. Invest. 73 (1984) 412-420
75. Sobrado, J., L. L. Moldawer, J. J. Pomposelli, E. A. Mascioli, V. K. Babayan, B. R. Bistrian, G. L. Blackburn: Lipid emulsions and reticuloendothelial system function in healthy and burned guinea pigs. Am. J. Clin. Nutr. 42 (1985) 855-863
76. Souba, W. W., K. Herskowitz, S. Klimberg, R. M. Salbum, D. A. Plumley, T. C. Flynn, E. M. I. Copeland: The effects of sepsis and endotoxemia on gut glutamine metabolism. Ann. Surg. 211 (1990) 543-549
77. Souba, W. W., V. S. Klimberg, D. A. Plumley, R. M. Salbum, T. C. Flynn, K. I. Bland, E. M. Copeland: The role of glutamine in maintaining a healthy gut and supporting the metabolic response to injury and infection. J. Surg. Res. 48 (1990) 383-391
78. Spengler, R. N., R. M. Allen, D. G. Remick, R. M. Stricter, S. L. Kunkel: Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor. J. Immunol. 145 (1990) 1430-1434
79. Stahl, W. M.: Acute phase protein response to tissue injury. Crit. Care Med. 15 (1987) 545-550
80. Starnes, H. F. J., R. S. Warren, M. Jeevanandam, J. L. Gabrilove, W. Larchian, H. F. Oettgen, M. F. Brennan: Tumor necrosis factor and the acute metabolic response to tissue injury in man. J. Clin. Invest. 82 (1988) 1321-1325
81. Suchner, U. M. M. Rothkopf: Metabolic effects of the neuroendocrine stress response. Anesth. Clin. N. Am. 6, No. 1 (1988) 1-23
82. Suchner, U., U. Senftleben, J. Askanazi, K. Peter: Nichtenergetische Bedeutung der enteralen Ernährung bei kritisch kranken Patienten. Infusionsther. Transfusionsmed. 20 (1993) 38-46
83. Suchner, U., U. Senftleben, T. Felbinger: Effect of dietary lipids on cellular elements and metabolism. Current Opinion in Gastroenterologv 11 (2) (1995) 151-160
84. Toyomizu, M. M. T. Clandinin: Effects of dietary protein and fat level on oxidative phosphorylation in rat heart mitochondria. Br. J. Nutr. 69 (1993) 7-102
85. Tracey, K. J., Y. Fong, D. G. Hesse, K. R. Manogue, A. T. Lee, G. C. Kuo, S. F. Lowry, A. Cerami: Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330 (1987) 662-664
86. Tracey, K. J., S. F. Lowry, T. J. Fahey, J. D. Albert, Y. Fong, D. Hesse, B. Beutler, K. R. Manogue, S. Calvano, H. Wei et al.: Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. Surg. Gynecol. Obstet. 164 (1987) 415-422
87. van der Hulst, R. R., B. K. van Kreel, M. F. von Meyenfeldt, R. J. Brummer, J. W. Arends, N. E. Deutz, P. B. Soeters: Glutamine and the preservation of gut integrity. Lancet 341 (1993) 1363-1365
88. Van der Poll, T., J. A. Romijn, E. Endert, J. J. Borm, H. R. Buller, H. P. Sauerwein: Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans. Am. J. Physiol. 261 (1991) E457-E465
89. Vary, T. C., J. H. Siegel, T. Nakatani, T. Sato, H. Aoyama: Regulation of glucose metabolism by altered pyruvate dehydrogenase activity. 1. Potential site of insulin resistance in sepsis. J. Parenter. Enteral. Nutr. 10 (1986) 351-355
90. Vary, T. C., J. H. Siegel, T. Nakatani, T. Sato, H. Aoyama: A biochemical basis for depressed ketogenesis in sepsis. J. Trauma 26 (1986) 419-425
91. Vaughan, G. M., R. A. Backer, R. H. Unger, M. G. Ziegler, T. M. Siler Khodr, B. A. J. Pruitt, A. D. J. Mason: Nonthyroidal control of metabolism after burn injury: possible role of glucagon. Metabolism 34 (1985) 637-641
92. Vo, N. M., M. Waycaster, R. V. Acuff, A. A. Lefemme: Effects of postoperative carbohydrate overfeeding. Am. Surg 53 (1987) 632-635
93. Wallace, C. D. Keast: Glutamine and macrophage function. Metabolism 41 (1992) 1016-1020
94. Wan, J. M. R. F. Grimble: Effect of dietary linoleate content on the metabolic response of rats to Escherichia coli endotoxin. Clinical Science 72 (1987) 383-385
95. Watters, J. M., P. Q. Bessey, C. A. Dinareib, S. M. Wolff, D. W. Wilmore: The induction of interleukin-1 in humans and its metabolic effects. Surgery 98 (1985) 298-306
96. Weissman, C.: The metabolic response to stress: an overview and update. Anesthesiology 73 (1990) 308-327
97. Wicklmayr, M., K. W. Jauch, K. Rett, W. Hartl, G. Dietze, B. Günther, H. Mehnert: Organstoffwechsel im postoperativen Streß. In: Ernährung und Intensivmedizin, H. W. Keller and J. M. Müller, editors. Schattauer, Stuttgart, New York (1989) 1-12
98. Wiener, M., M. M. Rothkopf, G. Rothkopf, J. Askanazi: Fat metabolism in injury and stress. Crit. Care Clin. 3 (1987) 25-56
99. Wilmore, D. W. L. H. Aulick: Metabolic changes in burned patients. Surg. Clin. North Am. 58 (1978) 1173-1187
100. Wolfe, R. R.: Carbohydrate metabolism in the critically ill patient. Implications for nutritional support. Crit. Care Clin. 3 (1987) 11-24
101. Wolfe, R. R.: Assessment of substrate cycling in humans using tracer methodology. In: Energy Metabolism: Tissue determinants and cellular corollaries. J. M. Kinney and H. N. Tucker, editors. Raven Press, Ltd. New York (1992) 495-523
102. Wolfe, R. R.: Carbohydrate metabolism and requirements. In: Clinical nutrition: Patenteral nutrition. J. L. Rombeau and M. D. Caldwell, editors. W. B. Saunders Company, Philadelphia (1993) 113-131
103. Wolfe, R. R., J. R. Allsorp, J. F. Burke: Glucose metabolism in man: responses to intravenous glucose infusion. Metabolism 28, No.3 (1979) 210-220
104. Wolfe, R. R., R. D. Goodenough, J. F. Burke, M. H. Wolfe: Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann. Surg. 197 (1983) 163-171
105. Wolfe, R. R., D. N. Herndon, F. Jahoor, H. Miyoshi, M. Wolfe: Effect of severe burn injury on substrate cycling by glucose and fatty acids. N. Engl. J. Med. 317 (1987) 403-408
106. Wolfe, R. R., T. F. J. O'Donnell, M. D. Stone, D. A. Richmand, J. F. Burke: Investigation of factors determining the optimal glucose infusion rate in total parenteral nutrition. Metabolism 29 (1980) 892-900
107. Yamazaki, K., A. Maiz, L. L. Moldawer, B. R. Bistrian, G. L. Blackburn: Complications associated with the overfeeding of infected animals. J. Surg. Res. 40 (1986) 152-158
108. Zaloga, G. P., P. Roberts: Permissive underfeeding. New Horizons 2 (2) (1994) 257-263
109. Ziegler, T. R., L S. Young, K. Benfell, M. Scheltinga, K. Hortos, R. Bye, F. D. Morrow, D. O. Jacobs, R. J. Smith, J. H. Antin et al.: Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann. Intern. Med. 116 (1992) 821-828