-
1
-
-
0000711103
-
-
Danheiser, R. L.; Gould, A. E.; Fernândez de la Pradilla, B.; Helgason, A. L. J. Org. Chem. 1994, 59, 5514.
-
(1994)
J. Org. Chem.
, vol.59
, pp. 5514
-
-
Danheiser, R.L.1
Gould, A.E.2
De La Fernândez, P.B.3
Helgason, A.L.4
-
2
-
-
0003417469
-
-
For reviews of azadienophiles in the Diels-Alder reaction, see: (a) Weinreb, S. M. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon Press: Oxford, 1991; Vol. 5, pp 401-413.
-
(1991)
Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon Press: Oxford
, vol.5
-
-
Weinreb, S.M.1
-
11
-
-
0028234425
-
-
Katagiri, N.; Nochi, H.; Kurimoto, A.; Sato, H.; Kaneko, C. Chem. Pharm. Bull. 1994, 42, 1251.
-
(1994)
Chem. Pharm. Bull.
, vol.42
, pp. 1251
-
-
Katagiri, N.1
Nochi, H.2
Kurimoto, A.3
Sato, H.4
Kaneko, C.5
-
12
-
-
0005380512
-
-
For reviews of the chemistry of Meldrum's acid and its derivatives see: (a) McNab, H. Chem. Soc. Rev. 1978, 7, 345.
-
(1978)
Chem. Soc. Rev.
, vol.7
, pp. 345
-
-
McNab, H.1
-
14
-
-
84944053729
-
-
For general reviews of the synthesis and chemistry of pyridines, see: (a) Scriven, E. F. V. In Comprehensive Heterocydic Chemistry; Boulton, A. J., McKillop, A., Eds.; Pergamon: Oxford, 1984; Vol. 2, Part 2A, pp 165-314.
-
(1984)
Comprehensive Heterocydic Chemistry; Boulton, A. J., McKillop, A., Eds.; Pergamon: Oxford
, vol.2
, Issue.PART 2A
-
-
Scriven, E.F.V.1
-
15
-
-
84944077969
-
-
(b) Yates, F. S. In Comprehensive Heterocydic Chemistry; Boulton, A. J., McKillop, A., Eds.; Pergamon: Oxford, 1984; Vol. 2, Part 2A, pp 511-524.
-
(1984)
Comprehensive Heterocydic Chemistry; Boulton, A. J., McKillop, A., Eds.; Pergamon: Oxford
, vol.2
, Issue.PART 2A
, pp. 511-524
-
-
Yates, F.S.1
-
16
-
-
33744879453
-
-
Tomasik, P.; Ratajewicz, Z. In PyridineMetal Complexes; Newkome, G. R., Strekowski, L., Eds.; The Chemistry of Heterocydic Compounds; Wiley: New York, 1985; Vol. 14, Part 6A.
-
(1985)
PyridineMetal Complexes; Newkome, G. R., Strekowski, L., Eds.; the Chemistry of Heterocydic Compounds; Wiley: New York
, vol.14
, Issue.PART 6A
-
-
Tomasik, P.1
Ratajewicz, Z.2
-
17
-
-
85034167878
-
-
Boulton, A. J.; McKillop, A., Eds.; Pergamon: Oxford
-
Jones, G. In Comprehensive Heterocydic Chemistry; Boulton, A. J.; McKillop, A., Eds.; Pergamon: Oxford, 1984; Vol. 2, Part 2A, pp 395510.
-
(1984)
Comprehensive Heterocydic Chemistry
, vol.2
, Issue.PART 2A
-
-
Jones, G.1
-
19
-
-
0017378913
-
-
(a) Enzell, C. R.; Wahlberg, I. In Progress in the Chemistry of Organic Natural Products; Herz, W.; Grisebach, H.; Kirby, G. W., Eds.; Springer-Verlag: New York, 1977; Vol. 34, p 1.
-
(1977)
Progress in the Chemistry of Organic Natural Products; Herz, W.; Grisebach, H.; Kirby, G. W., Eds.; Springer-Verlag: New York
, vol.34
, pp. 1
-
-
Enzell, C.R.1
Wahlberg, I.2
-
20
-
-
73649171243
-
-
Zechmeister, L., Ed.; Springer-Verlag: Vienna
-
(b) Birkinshaw, J. H.; Stickings, C. E. In Progress in the Chemistry of Organic Natural Products; Zechmeister, L., Ed.; Springer-Verlag: Vienna, 1962; Vol. 20, p 1.
-
(1962)
Progress in the Chemistry of Organic Natural Products
, vol.20
, pp. 1
-
-
Birkinshaw, J.H.1
Stickings, C.E.2
-
22
-
-
0002670124
-
-
Sauvage, J.-P., Hosseini, M. W., Eds.; Pergamon: New York
-
For reviews see: (a) Chambron, J.-C.; Dietrich-Buchecker, C.; Sauvage, J.-P. In Comprehensive Supramolecular Chemistry; Sauvage, J.-P., Hosseini, M. W., Eds.; Pergamon: New York, 1996; Vol. 9, pp 43-84.
-
(1996)
Comprehensive Supramolecular Chemistry
, vol.9
, pp. 43-84
-
-
Chambron, J.-C.1
Dietrich-Buchecker, C.2
Sauvage, J.-P.3
-
23
-
-
0002028351
-
-
Sauvage, J.-P., Hosseini, M. W., Eds.; Pergamon: New York
-
(b) Amabilino, D. B.; Raymo, F. M.; Stoddart, J. F. In Comprehensive Supramolecular Chemistry; Sauvage, J.-P., Hosseini, M. W., Eds.; Pergamon: New York, 1996; Vol. 9, pp 85-130.
-
(1996)
Comprehensive Supramolecular Chemistry
, vol.9
, pp. 85-130
-
-
Amabilino, D.B.1
Raymo, F.M.2
Stoddart, J.F.3
-
24
-
-
33744847126
-
-
Sauvage, J.P., Hosseini; M. W., Eds.; Pergamon: New York
-
Baxter, P. N. W. In Comprehensive Supramolecular Chemistry; Sauvage, J.P., Hosseini; M. W., Eds.; Pergamon: New York, 1996; Vol. 9, pp 165212.
-
(1996)
Comprehensive Supramolecular Chemistry
, vol.9
, pp. 165212
-
-
Baxter, P.N.W.1
-
28
-
-
0000600584
-
-
(b) Boger, D. L.; Corbett, W. L.; Curran, T. T.; Kasper, A. M. J. Am. Chem. Soc. 1991, 113, 1713.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 1713
-
-
Boger, D.L.1
Corbett, W.L.2
Curran, T.T.3
Kasper, A.M.4
-
30
-
-
0001216973
-
-
(a) Demoulin, A.; Gorissen, H.; Hesbain-Frisque, A.-M.; Ghosez, L. J. Am. Chem. Soc. 1975, 97, 4409.
-
(1975)
J. Am. Chem. Soc.
, vol.97
, pp. 4409
-
-
Demoulin, A.1
Gorissen, H.2
Hesbain-Frisque, A.-M.3
Ghosez, L.4
-
31
-
-
33744869247
-
-
(b) Sainte, F.; Serckx-Poncin, B.; Hesbain-Frisque, A.-M.; Ghosez, L. J. Am. Chem. Soc. 1982, 104, 1428.
-
(1982)
Chem. Soc.
, vol.104
, pp. 1428
-
-
Sainte, F.1
Serckx-Poncin, B.2
Hesbain-Frisque, A.-M.3
Am, G.L.J.4
-
32
-
-
0000047835
-
-
Serckx-Poncin, B.; Hesbain-Frisque, A.-M.; Ghosez, L. Tetrahedron Lett. 1982, 23, 3261.
-
(1982)
Tetrahedron Lett.
, vol.23
, pp. 3261
-
-
Serckx-Poncin, B.1
Hesbain-Frisque, A.-M.2
Ghosez, L.3
-
37
-
-
0343193917
-
-
(14)Meldrum's acid is itself sufficiently acidic to catalyze the nitrosation reaction. For the first report of the nitrosation of Meldrum's acid, see: Eistert, B.; Geiss, F. Chem. Ber. 1961, 94, 929.
-
(1961)
Chem. Ber.
, vol.94
, pp. 929
-
-
Eistert, B.1
Geiss, F.2
-
38
-
-
85034168481
-
-
Neutralization before the addition of TsCl helps prevent the acid-promoted addition of methanol to 8 (the product is obtained in 35% yield if buffer is not used)
-
Neutralization before the addition of TsCl helps prevent the acid-promoted addition of methanol to 8 (the product is obtained in 35% yield if buffer is not used).
-
-
-
-
40
-
-
33845280186
-
-
Evans, D. A.; Chapman, K. T.; Bisaha, J. J. Am. Chem. Soc. 1988, 110, 1238.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 1238
-
-
Evans, D.A.1
Chapman, K.T.2
Bisaha, J.3
-
41
-
-
0029921206
-
-
NCS in conjunction with NaOMe has recently been used for the oxidation of tetrahydropyridines to pyridines: De Kimpe, N.; Keppens, M.; Fonck, G. Chem. Commun. 1996, 635.
-
(1996)
Chem. Commun.
, pp. 635
-
-
De Kimpe, N.1
Keppens, M.2
Fonck, G.3
-
42
-
-
85034186766
-
-
note
-
Care must be exercised to avoid strongly basic workup conditions since the pyridine esters are sensitive to hydrolysis. This difficulty was circumvented by performing a neutral workup with pH 7 phosphate buffer.
-
-
-
-
43
-
-
84989036353
-
-
Deady, L. W.; Harrison, P. M.; Topsom, R. D. Org. Afagn. Reson. 1975, 7, 41.
-
(1975)
Org. Afagn. Reson.
, vol.7
, pp. 41
-
-
Deady, L.W.1
Harrison, P.M.2
Topsom, R.D.3
-
44
-
-
0030019368
-
-
Capasso, R.; Evidente, A.; Cutignano, A.; Vurro, M.; Zonno, M. C.; Bottalico, A. Phytochemistry 1996, 41, 1035.
-
(1996)
Phytochemistry
, vol.41
, pp. 1035
-
-
Capasso, R.1
Evidente, A.2
Cutignano, A.3
Vurro, M.4
Zonno, M.C.5
Bottalico, A.6
-
45
-
-
0009294724
-
-
(a) Hromatka, O.; Binder, D.; Stanetty, P.; Marischier, G. Monatsh. Chem. 1976, 707, 233.
-
(1976)
Monatsh. Chem.
, vol.707
, pp. 233
-
-
Hromatka, O.1
Binder, D.2
Stanetty, P.3
Marischier, G.4
-
46
-
-
0030052780
-
-
(b) Subramanyam, C.; Chattarjee, S.; Mallamo, J. P. Tetrahedron Lett. 1996, 37, 459.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 459
-
-
Subramanyam, C.1
Chattarjee, S.2
Mallamo, J.P.3
-
47
-
-
0018656314
-
-
Blank, B.; DiTullio, N. W.; Krog, A. J.; Saunders: H. L. J. Med. Chem. 1979, 22, 840.
-
(1979)
J. Med. Chem.
, vol.22
, pp. 840
-
-
Blank, B.1
Ditullio, N.W.2
Krog, A.J.3
Saunders, H.L.4
-
48
-
-
0008973992
-
-
(a) Yabuta, T.; Kambe, K; Hayashi, T. J. Agric. Chem. Soc. Jpn. 1934, 10, 1059.
-
(1934)
J. Agric. Chem. Soc. Jpn.
, vol.10
, pp. 1059
-
-
Yabuta, T.1
Kambe, K.2
Hayashi, T.3
-
50
-
-
0014516957
-
-
Hidaka, H.; Nagatsu, T.; Takeya, K. J. Antibiot. 1969, 22, 228.
-
(1969)
J. Antibiot.
, vol.22
, pp. 228
-
-
Hidaka, H.1
Nagatsu, T.2
Takeya, K.3
-
51
-
-
0014710432
-
-
Nagatsu, T.; Hidaka, H.; Kuzuya, H.; Takeya, K.; Umezawa, H.; Takeuchi, T.; Suda, H. Biochem. Pharmacol. 1970, 19, 35.
-
(1970)
Biochem. Pharmacol.
, vol.19
, pp. 35
-
-
Nagatsu, T.1
Hidaka, H.2
Kuzuya, H.3
Takeya, K.4
Umezawa, H.5
Takeuchi, T.6
Suda, H.7
-
52
-
-
0014605044
-
-
(e) Suda, H.; Takeuchi, T.; Nagatsu, T.; Matsuzaki, M.; Matsumoto, L; Umezawa, H. Chem. Pharm. Bull. 1969, 17, 2377.
-
(1969)
Chem. Pharm. Bull.
, vol.17
, pp. 2377
-
-
Suda, H.1
Takeuchi, T.2
Nagatsu, T.3
Matsuzaki, M.4
Matsumoto, L.5
Umezawa, H.6
-
53
-
-
33744869246
-
-
(f) Claydon, N.; Grove, J. F.; Pople, M. Phytochemistry 1977, 16, 603.
-
(1977)
Phytochemistry
, vol.16
, pp. 603
-
-
Claydon, N.1
Grove, J.F.2
Pople, M.3
-
55
-
-
0030019368
-
-
(h) Capasso, R.; Evidente, A.; Cutignano, A.; Vurro, M.; Zonno, M. C.; Bottalico, A. Phytochemistry 1996, 41, 1035.
-
(1996)
Phytochemistry
, vol.41
, pp. 1035
-
-
Capasso, R.1
Evidente, A.2
Cutignano, A.3
Vurro, M.4
Zonno, M.C.5
Bottalico, A.6
-
56
-
-
85034184306
-
-
note
-
Fusaric acid is a nanomolar inhibitor of dopamine /J-hydroxylase (IC50 = 3.0 x 10-" M), see: ref 24d.
-
-
-
-
57
-
-
0006309218
-
-
Steiner, K.; Graf, U.; Hardegger, E. Helv. Chim.Acta 1971, 54, 845.
-
(1971)
Helv. Chim.Acta
, vol.54
, pp. 845
-
-
Steiner, K.1
Graf, U.2
Hardegger, E.3
-
58
-
-
84980165613
-
-
(a) Plattner, PL A.; Keller, W.; Boiler, A. Helv. Chim. Acta 1954, 37, 1379.
-
(1954)
Helv. Chim. Acta
, vol.37
, pp. 1379
-
-
Plattner, P.L.A.1
Keller, W.2
Boiler, A.3
-
62
-
-
0000517071
-
-
(e) Sagi, M.; Amano, M.; Konno, S.; Yamanaka, H. Heterocycles 1989, 29, 2249.
-
(1989)
Heterocycles
, vol.29
, pp. 2249
-
-
Sagi, M.1
Amano, M.2
Konno, S.3
Yamanaka, H.4
-
66
-
-
37049095993
-
-
Klusener, P. A. A.; Hommes, H. H.; Verkruijsse, H. D.; Brandsma, L. Chem. Commun. 1985, 1677.
-
(1985)
Chem. Commun.
, pp. 1677
-
-
Klusener, P.A.A.1
Hommes, H.H.2
Verkruijsse, H.D.3
Brandsma, L.4
-
68
-
-
0344059774
-
-
(b) Ueno, Y.; Sano, H.; Aoki, S.; Okawara, M. Tetrahedron Lett. 1981, 28, 2675.
-
(1981)
Tetrahedron Lett.
, vol.28
, pp. 2675
-
-
Ueno, Y.1
Sano, H.2
Aoki, S.3
Okawara, M.4
-
70
-
-
85034183588
-
-
The Mosher ester of racemic 34 was also prepared, and the diastereomers were found to be well resolved by both 'H and 19F NMR spectroscopy
-
The Mosher ester of racemic 34 was also prepared, and the diastereomers were found to be well resolved by both 'H and 19F NMR spectroscopy.
-
-
-
-
71
-
-
85034164045
-
-
note
-
The isolation of (S)-(+)-fusarinolic acid was complicated by its high solubility in aqueous solution. Fortunately, (SH+)-fusarinolic acid could be recovered from an appropriately buffered (pH 2.5) aqueous solution by continuous liquid-liquid extraction with dichloromethane for 2 days.
-
-
-
-
72
-
-
3242744539
-
-
and references therein
-
(a) Gassman, P. G. Ace. Chem. Res. 1970, 3, 26 and references therein,
-
(1970)
Chem. Res.
, vol.3
, pp. 26
-
-
Ace, G.P.G.1
-
74
-
-
0001631416
-
-
Huffman, R. V.; Kumar, A.; Buntain, G. A. J. Am. Chem. Soc. 1985, 107, 4731.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 4731
-
-
Huffman, R.V.1
Kumar, A.2
Buntain, G.A.3
-
75
-
-
85034197289
-
-
note
-
We briefly conducted experiments with the aim of trapping the putative intermediate 44 with cyanide ion. A variety of cyanide sources and solvents were examined, but only the normal pyrroline product could be isolated. Attack of cyanide at the sulfonyl group of 43 may be responsible for pyrroline formation in these reactions.
-
-
-
-
80
-
-
0000693157
-
-
Traynelis, V. J.; Hergenrother, W. L.; Livingston, J. R.; Valicenti, J. A. J. Org. Chem. 1962, 27, 2377.
-
(1962)
J. Org. Chem.
, vol.27
, pp. 2377
-
-
Traynelis, V.J.1
Hergenrother, W.L.2
Livingston, J.R.3
Valicenti, J.A.4
-
81
-
-
0000112724
-
-
Jung, M. E.; McCombs, G. A.; Takeda, Y.; Pan, Y.-G. J. Am. Chem. Soc. 1981, 103, 6677.
-
(1981)
J. Am. Chem. Soc.
, vol.103
, pp. 6677
-
-
Jung, M.E.1
McCombs, G.A.2
Takeda, Y.3
Pan, Y.-G.4
|