Determination of artesunate by capillary electrophoresis with low UV detection and possible applications to analogues

Journal of Chromatographic Science

Volumn 34, Issue 6, 1996, Pages 276-281

  D'Hulst, A ^a   Augustijns, P ^a   Arens, S ^a   Van Parijs, L ^a   Colson, S ^a   Verbeke, N ^a   Kinget, R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000556360     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. D. Klayman. Qinghaosu (artemisinin): an antimalarial drug from China. Science 228: 1049-55 (1985).
2. X. Luo and C. Shen. The chemistry, pharmacology, and clinical applications of qirtghaosu (artemisinin) and its derivatives. Med. Res. Rev. 7: 29-52 (1987).
3. Trans. Royal Soc. Trop. Med. Hyg. 88 (Suppl 1): (1994).
4. A. Theoharides, M. Smyth, R. Ashmore, J. Halverson, Z. Zhou, W. Ridder, and A. Lin. Determination of dihydroqinghaosu in blood by pyrolysis gas chromatography/mass spectrometry. Anal. Chem. 60: 115-20 (1988).
5. J. Ferreira, D. Charles, K. Wood, J. Janick, and J. Simon. A comparison of gas chromatography and high performance liquid chromatography for artemisinin analyses. Phytochem. Anal. 5: 116-20 (1994).
6. V. Melendez, J. Peggins, T. Brewer, and A. Theoharides. Determination of the antimalarial arteether and its deethylated metabolite dihydroartemisinin in plasma by high performance liquid chromatography with reductive electrochemical detection. J. Pharm. Sci. 80: 132-38 (1991).
7. Z. Zhou, J. Anders, H. Chung, and A. Theoharides. Analysis of artesunic acid and dihydroqinghaosu in blood by high performance liquid chromatography with reductive electrochemical detection. J. Chromatogr. 414: 77-90 (1987).
8. M. Green, D. Mount, G. Todd, and A. Capomacchia. Chemiluminescent detection of artemisinin - Novel endoperoxide analysis using luminol without hydrogen peroxide. J. Chromatogr. A. 695: 237-42 (1995).
9. M.-Y. Zeng and L.-N. Li. Chemical transformations of Qinghaosu, a peroxide antimalarial. Tetrahedron. 39: 2941-46 (1983).
10. P. Edlund, D. Westerlund, J. Carlqvist, B. Wu, and Y. Jin. Determination of artesunate and dihydroartemisinin in plasma by liquid chromatography with post-column derivatization and UV-detection. Acta Pharm. Suec. 21: 223-34 (1984).
11. H. ElSohly, E. Croom, and M. ElSohly. Analysis of the antimalarial sesquiterpene artemisinin in Artemisia annua by high-performance liquid chromatography (HPLC) with postcolumn derivatization and ultraviolet detection. Pharm. Res. 4: 258-60 (1987).
12. O. Idowu, G. Edwards, S. Ward, M. Orme, and A. Breckenridge. Determination of arteether in blood plasma by high-performance liquid chromatography with ultraviolet detection after hydrolysis with acid. J. Chromatogr. 493: 125-36 (1989).
13. S. Zhao and M.-Y. Zeng. Application of precolumn reaction to high-performance liquid chromatography of Qinghaosu in animal plasma. Anal. Chem. 58: 289-92 (1986).
14. D. Mount, G. Todd, and V. Navaratnam. Packed-column super-critical fluid chromatography of artemisinin (qinghaosu) with electron-capture detection. J. Chromatogr. B. 666: 183-87 (1995).
15. M. Albin, P. Grossman, and S. Moring. Sensitivity enhancement for capillary electrophoresis. Anal. Chem. 65: A489-97 (1993).
16. J. Knox. Thermal effects and band spreading in capillary electroseparation. Chromatographia 26: 329-37 (1988).
17. J. Jorgenson and K. Lukacs. Zone electrophoresis in open-tubular glass capillaries. Anal. Chem. 53: 1298-1302 (1981).
18. D. Burgi and R.-L. Chien. Optimization in sample stacking for high-performance capillary electrophoresis. Anal. Chem. 63: 2042-47 (1991).
19. J. Vindevogel and P. Sandra. Introduction to Micellar Electrokinetic Chromatography. Hüthig, Heidelberg, Germany, 1992, pp 121-22.