Directed ortho-lithiation on solid phase

Journal of Organic Chemistry

Volumn 63, Issue 21, 1998, Pages 7418-7420

  Havez, Sophie ^a   Begtrup, Mikael ^a   Vedsø, Per ^b   Andersen, Kim ^b   Ruhland, Thomas ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000553432     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo981145f     Document Type: Article

References (26)

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23. If the procedure was performed on a smaller scale (with ca. 5 g of resin), a loading of 1.07 mmol/g corresponding to 88% of the maximal theoretical loading was attained.
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26. 1-Hydroxy-2-benzoylimidazole seems to be a weaker base than the other 2-substituted 1-hydroxyimidazoles reported. Therefore, it was conveniently isolated as the free base.