Development of Systemic Immunologic Responses Against Hepatic Metastases during Gene Therapy for Peritoneal Carcinomatosis with Retroviral HS-tk and Ganciclovir

Journal of Gastrointestinal Surgery

Volumn 1, Issue 6, 1997, Pages 527-533

  Misawa, Takeyuki ^a   Chiang, Mimi H ^a   Pandit, Lalita ^a   Gordon, Erlinda M ^a   Anderson, W French ^a   Parekh, Dilip ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000494998     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1091-255X(97)80069-8     Document Type: Article

References (16)

1. Baker AR, Weber JS. Treatment of malignant ascites in cancer. In DeVita VT Jr, Hellman S, Rosenberg SA, eds. Principles and Practice of Oncology, vol. 2, 4th ed. Philadelphia: JB Lippincott, 1993, pp 2255-2261.
2. Klapdor R. Perspectives in chemotherapy of pancreatic cancer. Eur J Surg Oncol 1991;17:153-166.
3. Culver KW, Ram Z, Wallbridge S, et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumor. Science 1992;256:1550-1552.
4. Moolten FL, Wells JM. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst 1990;82:297-300.
5. Smythe RW, Hwang HC, Elshami AA, et al. Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg 1995;222:78-86.
6. Marshall E. Gene therapy's growing pains. Science 1995; 269:1050-1055.
7. Yang L, Hwang R, Pandit L, Gordon EM, Parekh D. Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral HS-tk vector supernatant and ganciclovir. Ann Surg 1996;224:405-417.
8. Barba D, Hardin J, Sadelain M, Gage FH. Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc Natl Acad Sci USA 1994;91:4348-4352.
9. Tapscott SJ, Miller AD, Olson JM, et al. Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection. Proc Natl Acad Sci USA 1994;91:8185-8189.
10. Martin MS, Bastien H, Martin F, et al. Transplantation of intestinal carcinoma in inbred rats. Biomed 1973;19:555-558.
11. Dunnington D, Burscarino C, Gennaro E, Greig R, Poste G. Characterization of an animal model of metastatic colon carcinoma. Int J Cancer 1987;39:248-254.
12. Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes. Paradigm for a prospective cancer control strategy. Cancer Res 1986;46:5276-5281.
13. Anderson FW. Human gene therapy. Science 1992;256:808-813.
14. Caruso M, Panis Y, Gagnadeep S, et al. Regression of established macroscopic liver metastases after in situ transduction of a suicide gene. Proc Natl Acad Sci USA 1993;90:7024-7028.
15. Chen S, Li Chen XH, Kosai K, Wang Y, Finegold MJ. Combination gene therapy for liver metastases of colon carcinoma in vivo [abstr] Am Assoc Cancer Res, 1996.
16. Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulation factor stimulates potent, speccific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993;90:3539-3543.