Novel Irreversible Ligands Specific For “Peripheral” Type Benzodiazepine Receptors: (±)-, (+)-, and (-)-1-(2-chloropheny1)-n-(1-methylpropy1)-n-(2-isothiocyanatoethyl)-3-isoquinolinecarboxarnide and 1-(2-isothiocyanatoethyl)-

Journal of Medicinal Chemistry

Volumn 30, Issue 10, 1987, Pages 1901-1905

  Newman, Amy Hauck ^b   Lueddens, Hartmut W M ^a   Skolnick, Phil ^a   Rice, Kenner C ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4' CHLORODIAZEPAM; 4' CHLORODIAZEPAM H 3; 7 CHLORO 5 (4 CHLOROPHENYL) 1,3 DIHYDRO 1 (2 ISOTHIOCYANATOETHYL) 2H 1,4 BENZODIAZEPIN 2 ONE; BENZODIAZEPINE RECEPTOR; N SEC BUTYL 1 (2 CHLOROPHENYL) N (2 ISOTHIOCYANATOETHYL) 3 ISOQUINOLINECARBOXAMIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE H 3; UNCLASSIFIED DRUG;

ANIMAL CELL; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; PH; STRUCTURE ACTIVITY RELATION;

ANIMAL; BENZODIAZEPINONES; BRAIN; HYDROGEN-ION CONCENTRATION; ISOQUINOLINES; KIDNEY; MALE; RATS; RATS, INBRED STRAINS; RECEPTORS, GABA-A; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0000461929     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00393a036     Document Type: Article

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