[trans-en2Os(η-H2)]2+ as an 1H NMR probe for the coordination of some anticancer metal complexes to deoxyguanotide

Science in China, Series B: Chemistry

Volumn 40, Issue 5, 1997, Pages 541-547

  Yang, Pin ^a   Guo, Maolin ^a   Li, Qingshan ^b   Tian, Yanni ^b   Li, Zai Wei ^c   Taube, Henry ^c  

^a SHANXI UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c STANFORD UNIVERSITY   (United States)

Author keywords

1H NMR probe; Deoxyguanylic acid; Metal anticancer complex; Molecular hydrogen complex of osmium

Indexed keywords

EID: 0000408959     PISSN: 10069291     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02875425     Document Type: Article

References (15)

1. 1H NMR recognition probe, Science, 1992, 256: 210.
2. Sundquist, W.I., Lippard, S.J., The coordination chemistry of platinum anticancer drugs and related compounds with DNA, Coord. Chem. Rev., 1990, 100: 293.
3. Umapathy, P., The chemical and biochemical consequences of the binding of the antitumor drug cisplatin and other platinum group metal complexes to DNA, Coord. Chem. Rev., 1989, 95: 129.
4. Koepf-Maier, P., Koepf, H., Non-platinum-group metal antitumor agents: history, current status and perspectives, Chem. Rev., 1987, 87: 1137.
5. Saxena, A.K., Organotin compounds and cancer chemotherapy, Coord. Chem. Rev., 1989, 95: 109.
6. 2, M=Ti, V, Zr: Aqueous kinetics, equilibria, and mechanistic implications for a new class of antitumor agents, J. Am. Chem. Soc., 1985, 107: 947.
7. Kuo, L.Y., Kanatzidis, M.G., Sabat, M. et al., Metallocene antitumor agents: Solution and solid-state molybdenocene coordination chemistry of DNA constituents, J. Am. Chem. Soc., 1991, 113: 9027.
8. 2 complexes of osmium ammines by facile substitution, J. Am. Chem. Soc., 113: 8946.
9. Wilkinson, G., Birmingham, J.M., Bis-cyclopentadienyl compounds of Ti, Zr, V, Nb and Ta, J. Am. Chem. Soc., 1954, 76: 4281.
10. Crowe, A.J., Smith, P.J., The synthesis and tin-119m Mössbauer spectra of some diorganotin dihalide and dipseudohalide complexes with nitrogen- and oxygen-donor ligands, J. Organomet. Chem., 1982, 224: 223.
11. Crowe, A.J., Smith, P.J., Atassi, G., Investigation into the antitumor activity of organotin compounds (I): Diorganotin dihalides and dipseudohalide complexes, Chem-Bio. Interact., 1980, 32: 171.
12. Inagaki, K., Dijt, F.J., Lempers, E.L.M. et al., Bulky ligand substituent effect on the reaction of 5′-GMP with Pt(1,3-diamine): Rotation of 5′-GMP about the Pt-N bond and kinetic effects, Inorg. Chem., 1988, 27: 382.
13. 1H NMR spectroscopic studies of C2′-endo, C3′-endo sugar ring conformations in 5′-GMP and 3′-GMP nucleotides and their platinum complexes, Inorg. Chim. Acta, 1986, 123: L3.
14. Marzilli, L.G., Reily, M.D., Heyl, R.B. et al., Evidence for similar structural changes on binding of platinum anti-tumor agents to DNA and nucleosomes, FEBS, 1984, 176: 389.
15. 2, with nucleotides and phosphoesters: Mechanistic implication for a new class of antitumor agents, J. Am. Chem. Soc., 1986, 108: 7263.