Enantioselective synthesis of 2-substituted 4-aminobutanoic acid (GABA) analogues via cyanomethylation of chiral enolates

Journal of the Chemical Society - Perkin Transactions 1

Volumn , Issue 7, 1996, Pages 621-627

  Azam, Shamim ^a   D'Souza, Alice A ^a   Wyatt, Peter B ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000401502     PISSN: 0300922X     EISSN: None     Source Type: Journal    
DOI: 10.1039/p19960000621     Document Type: Article

References (12)

1. P. L. McGeer and E. G. McGeer, in Basic Neurochemistry, eds. G. Siegel, B. Agranoff, R. W. Albers and P. Molinoff, Raven, New York, 4th edn., 1989.
2. N. Suman-Chauhan, L. Webdale, D. R. Hill and G. N. Woodruff, Eur. J. Pharmacol. Mol. Pharmacol. Sect., 1993, 244, 293.
3. D. A. Evans, M. D. Ennis and D. J. Mathre, J. Am. Chem. Soc., 1982, 104, 1737.
4. A. Fadel and J. Salaün, Tetrahedron Lett., 1988, 29, 6257.
5. A. Solladié-Cavallo and M. C. Simon, Tetrahedron Lett., 1989, 30, 6011.
6. D. A. Evans, J. Bartroli and T. L. Shih, J. Am. Chem. Soc., 1981, 103, 2127.
7. Compare e.g., X. Qian, K. C. Russell, L. W. Boteju and V. J. Hruby, Tetrahedron, 1995, 51, 1033.
8. R. Adams and D. Fles, J. Am. Chem. Soc., 1959, 81, 4946.
9. G. Bettoni, C. Cellucci and F. Berardi, J. Heterocycl. Chem., 1980, 17, 603.
10. S. Malik and P. B. Wyatt, Synth. Commun., 1993, 23, 1047.
11. B. T. Lotz and M. J. Miller, J. Org. Chem., 1993, 58, 618;
12. R. N. Guthikonda, L. D. Cama and B. G. Christensen, J. Am. Chem. Soc., 1974, 96, 7584.