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58149324217
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119Sn NMR spectrum by shielding the signal (δ = -129.1 ppm for 2a compared to -81.8 ppm for 2b and -84.6 ppm for 7). For similar phenomena observed on monoallyltrihalogenotins see also: Fouquet, E.; Gabriel, A.; Maillard, B.; Pereyre, M. Bull. Soc. ChIm. Fr. 1995, 132, 590.
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18
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84858824332
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v anion A, and the third equivalent is consumed for the halogen exchange of the tin-halogen bond created during the coupling
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v anion A, and the third equivalent is consumed for the halogen exchange of the tin-halogen bond created during the coupling.
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25
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84859344280
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84858832457
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Eds.; Cambridge
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28
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84858832458
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Typical procedure: 1-Iodohexyne (1.85 mmol) was added to a solution of stannylene 1 (1.85 mmol) in THF (4 mL) and stirred for 30 min at rt. TBAF (5.9 mL, 1 M) was added, after concentration, dioxane (8 mL), iodobenzene (1.23 mmol), and tetrakis(triphenylphosphine)palladium (0.015 mmol) were added, and the reaction mixture was refluxed for 2 h. After cooling and removal of the solvent, purification on silica gel afforded 20 in 83% yield
-
Typical procedure: 1-Iodohexyne (1.85 mmol) was added to a solution of stannylene 1 (1.85 mmol) in THF (4 mL) and stirred for 30 min at rt. TBAF (5.9 mL, 1 M) was added, after concentration, dioxane (8 mL), iodobenzene (1.23 mmol), and tetrakis(triphenylphosphine)palladium (0.015 mmol) were added, and the reaction mixture was refluxed for 2 h. After cooling and removal of the solvent, purification on silica gel afforded 20 in 83% yield.
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30
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0026517852
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