Plant lipoxygenase: Structure and function

Annual Review of Plant Physiology and Plant Molecular Biology

Volumn 42, Issue 1, 1991, Pages 145-188

  Siedow, James N ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

Jasmonic acid; Lipid peroxidation; Lipoxygenase pathway; Plant stress response

Indexed keywords

EID: 0000328572     PISSN: 10402519     EISSN: None     Source Type: Journal    
DOI: 10.1146/annurev.pp.42.060191.001045     Document Type: Article

References (188)

1. Aldridge, D. C., Galt, S., Giles, D., Turner, W. B. 1971. Metabolites of Lasidioplodia theobromae. J. Chem. Soc., pp. 1623-27
2. Altschuler, M., Collins, G. B., Hildebrand, D. F. 1989. Developmental expression of lipoxygenases in soybeans. Plant Sci. 63:151-58
3. Anderson, J. M. 1989. Membrane derived fatty acids as precursors to second messengers. In Second Messengers in Plant Growth and Development, ed. W. F. Boss, D. J. Morre, pp. 181-212. New York: Allen R. Liss
4. Anderson, J. M., Spilatro, S. R., Klauer, S. F., Franceschi, V. R. 1989. Jasmonic acid dependent increase in the level of vegetative storage protein in soybean. Plant Sci. 62:45-52
5. Andre, E., Hou, K.-W. 1932. The presence of a lipoid oxidase in soybean, Glycine soya, Lieb. C. R. Acad. Sci. (Paris) 194:645-47
6. Anstis, P. J. P., Friend, J. 1974. The isozyme distribution of etiolated pea seedling lipoxygenase. Planta 115:329-35
7. Axelrod, B. 1974. Lipoxygenases. ACS Adv. Chem. Ser. 136:324-48
8. Axelrod, B., Cheesbrough, T. M., Laasko, S. 1981. Lipoxygenase from soybeans. Methods Enzymol. 71:441-51
9. Balcarek, J. M., Theisen, T. W., Cook, M. N., Varrichio, A., Hwang, S.-M., Strohsacker, M. W., Crooke, S. T. 1988. Isolation and characterization of a cDNA encoding rat 5-lipoxygenase. J. Biol. Chem. 263:13937-41
10. Beneytout, J.-L., Andrianarison, R.-H., Rakotoarisoa, Z., Tixier, M. 1989. Properties of a lipoxygenase in green algae (Oscillatoria sp.). Plant Physiol. 91:367-72
11. Beneytout, J. L., Najid, A., Tixier, M. 1988. Changes in lipoxygenase activity during seedling development of Lupinus albus. Plant Sci. 58:35-41
12. Bild, G. S., Ramadoss, C. S., Axelrod, B. 1977. Effect of substrate polarity on the activity of soybean lipoxygenase isozymes. Lipids 12:732-35
13. Bonner, J., English, J. 1938. A chemical and physiological study of traumatin, a plant wound hormone. Plant Physiol. 13:331-48
14. Bookjans, G., Altschuler, M., Brockman, J., Yenofsky, R., Polacco, J., et al. 1988. Molecular biological studies of plant lipoxygenases. In Proceedings of the World Conference on Biotechnology for the Fat and Oil Industry, ed. T. H. Applewhite, pp. 301-4. Urbana: Am. Oil Chem. Soc. Press
15. Bousquet, J. P., Thimann, K. V. 1984. Lipid peroxidation forms ethylene from 1-aminocyclopropane-1-carboxylic acid and may operate in leaf senescence. Proc. Natl. Acad. Sci. USA 81:1724-27
16. Boyington, J. C., Gaffney, B. J., Amzel, L. M. 1990. Crystallization and preliminary X-ray analysis of soybean lipoxygenase-1, a non-heme iron-containing dioxygenase. J. Biol. Chem. 265:12771-73
17. Bradley, F. C., Lindstedt, S., Lipscomb, J. D., Que, L., Row, A. L., Rundgren. M. 1986. 4-hydroxyphenylpyruvate dioxygenase is an iron-tyrosinate protein. J. Biol. Chem. 261:11693-96
18. Casey, R., Domoney, C., Nielsen, N. C. 1985. Isolation of a cDNA clone for pea (Pisum sativum) seed lipoxygenase. Biochem. J. 232:79-85
19. Chan, H. W. S. 1973. Soy-bean lipoxygenase: an iron-containing dioxygenase. Biochim. Biophys. Acta 327:32-35
20. Chothia, C., Finkelstein, A. V. 1990. The classification and origins of protein folding patterns. Annu. Rev. Biochem. 59:1007-39
21. Chou, P. Y., Fasman, G. D. 1978. Emperical predictions of protein conformation. Annu. Rev. Biochem. 47: 251-76
22. Christopher, J. P., Pistorius, E. K., Axelrod, B. 1970. Isolation of an isozyme of soybean lipoxygenase. Biochim. Biophys. Acta 198:12-19
23. Christopher, J. P., Pistorius, E. K., Axelrod, B. 1972. Isolation of a third isozyme of soybean lipoxygenase. Biochim. Biophys. Acta 284:54-62
24. Corey, E. J. 1986. Mechanism of enzymic iipoxygenation of arachidonic acid. Key role of organoiron intermediates. In Stereochemistry of Organic and Bioorganic Transformations, ed. W. Bartmann, K. B. Sharpless, pp. 1-12. Weinheim, F.R.G.: VCH Publishers
25. Corey, E. J., d'Alarcao, M., Matsuda, S. P. T. 1986. A new irreversible inhibitor of soybean lipoxygenase; relevance to mechanism. Tetrahedron Lett. 27:3585-88
26. Corey, E. J., Nagata, R. 1987. Evidence in favor of an organoiron-mediated pathway for lipoxygenation of fatty acids by soybean lipoxygenase. J. Am. Chem. Soc. 109:8107-8
27. Davies, C. S., Nielsen, N. C. 1986. Genetic analysis of a null-allele for lipoxygenase-2 in soybean. Crop Sci. 26:460-63
28. deGroot, J. J. M. C., Garssen, G. J., Veldink, G. A., Vliegenthart, J. F. G., Boldingh, J. 1975. On the interaction of soybean lipoxygenase-1 and 13-L-hydroperoxylinoleic acid, involving yellow and purple coloured enzyme species. FEBS Lett. 56:50-54
29. deGroot, J. J. M. C., Vliegenthart, J. F. G., Boldingh, J., Weber, R., Van Gelder, B. F. 1975. Demonstration by EPR spectroscopy of a functional role of iron in soybean lipoxygenase-1. Biochim. Biophys. Acta 377:71-79
30. Deisenhofer, J., Epp, O., Miki, K., Huber, R., Michel, H. 1985. Structure of the protein subunits in the photosynthetic reaction center of Rhodopseudomonas viridis at 3A resolution. Nature 318:618-24
31. Dhindsa, R. S., Plumb-Dhindsa, P. L., Reid, D. M. 1982. Leaf senescence and lipid peroxidation: Effects of some phytohormones and scavengers of free radicals and singlet oxygen. Physiol. Plant. 56:453-57
32. Dixon, R. A. F., Jones, R. E., Diehl, R. E., Bennett, C. D., Kargman, S., Rouzer, C. A. 1988. Cloning of the cDNA for human 5-lipoxygenase. Proc. Natl. Acad. Sci. USA 85:416-20
33. Dixon, R. A., Lamb, C. J. 1990. Molecular communication in interactions between plants and microbial pathogens. Annu. Rev. Plant Physiol. Plant Mol. Biol. 41:339-67
34. Domoney, C., Firmin, J. L., Sidebottom, C., Haling, P. M., Slabas, A., Casey, R. 1990. Lipoxygenase heterogeneity in Pisum sativum. Planta 181: 35-43
35. Draheim, J. E., Carroll, R. T., McNemar, T. B., Dunham, W. R., Sands, R. H., Funk, M. O. 1989. Lipoxygenase isozymes: a spectroscopic and structural characterization of soybean seed enzymes. Arch. Biochem. Biophys. 269:208-18
36. Duine, J. A., Jongejan, J. A. 1989. Quinoproteins, enzymes with pyrroloquinoline quinone as cofactor. Annu. Rev. Biochem. 58:403-26
37. Dunham, W. R., Carroll, R. T., Thompson, J. F., Sands, R. H., Funk, M. O. 1990. The initial characterization of the iron environment in lipoxygenase by Mössbauer spectroscopy. Eur. J. Biochem. 190:611-17
38. Dupont, J., Rustin, P., Lance, C. 1982. Interaction between mitochondrial cytochromes and linoleic acid hydroperoxide: possible confusion with lipoxygenase and alternative pathway. Plant Physiol. 69:1308-14
39. Duran, N. 1982. Singlet oxygen in biological processes. In Chemical and Biological Generation of Excited States, ed. A. Walderman, G. Cilento, pp. 345-69. New York: Academic
40. Haling, P. M., Casey, R. 1988. Complete amino acid sequence of a pea (Pisum sativum) seed lipoxygenase predicted from a near full-length cDNA. Biochem. J. 253:915-18
41. Egmond, M. R., Veldink, G. A., Vliegenthart, J. F. G., Boldingh, J. 1973. C-11 H-abstraction from linoleic acid, the rate-limiting step in lipoxygenase catalysis. Biochem. Biophys. Res. Commun. 54:1178-84
42. Egmond, M. R., Vliegenthart, J. F. G., Boldingh, J. 1972. Stereospecificity of the hydrogen abstraction at carbon atom n-8 in the oxygenation of linoleic acid by lipoxygenases from corn germs and soya beans. Biochem. Biophys. Res. Commun. 48:1055-60
43. Elthon, T. E., McIntosh, L. 1987. Identification of the alternative terminal oxidase of higher plant mitochondria. Proc. Natl. Acad. Sci. USA 84:8399-403
44. Elthon, T. E., Nickels, R. L., McIntosh, L. 1989. Monoclonal antibodies to the alternative oxidase of higher plant mitochondria. Plant Physiol. 89:1311-17
45. Engelman, D. M., Steitz, T. A., Goldman, A. 1986. Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins. Annu. Rev. Biophys. Biophys. Chem. 15:321-53
46. English, J., Bonner, J., Haagen-Smit, A. J. 1939. Structure and synthesis of a plant wound hormone. Science 90:329
47. Eskin, N. A. M., Grossman, S., Pinsky, A. 1977. Biochemistry of lipoxygenase in relation to food quality. Crit. Rev. Food Sci. Nutr. 9:1-41
48. Farmer, E. E., Pearce, G., Ryan, C. A. 1989. In vitro phosphorylation of plant plasma membrane proteins in response to the proteinase inhibitor inducing factor. Proc. Natl. Acad. Sci. USA 86: 1539-42
49. Farmer, E. E., Ryan, C. A. 1990. Interplant communication: airborne methyl jasmonate induces synthesis of proteinase inhibitors in plant leaves. Proc. Natl. Acad. Sci. USA 87:7713-16
50. Feiters, M. C., Aasa, R., Malmstrom, B. G., Veldink, G. A., Vliegenthart, J. F. G. 1986. Spectroscopic studies on the interactions between lipoxygenase-2 and its product hydroperoxides. Biochim. Biophys. Acta 873:182-89
51. Feiters, M. C., Veldink, G. A., Vliegenthart, J. F. G. 1986. Heterogeneity of soybean lipoxygenase-2. Biochim. Biophys. Acta 870:367-71
52. Finazzi-Agro, A., Avigliano, L., Veldink, G. A., Vliegenthart, J. F. G., Boldingh, J. 1973. The influence of oxygen on the fluorescence of lipoxygenase. Biochim. Biophys. Acta 326:462-70
53. Fisher, S. M., Baldwin, J. K., Jasheway, D. W., Patrick, K. E., Cameron, G. S. 1988. Phorbol ester induction of 8-lipoxygenase in inbred SENCAR (SSIN) but not C57BL/6J mice correlated with hyperplasia, edema, and oxidant generation but not ornithine decarboxylase induction. Cancer Res. 48:658-64
54. Fleming, J., Thiele, B. J., Chester, J., O'Prey, J., Janetzki, S., et al. 1989. The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases. Gene 79:181-88
55. Fobel, M., Lynch, D. V., Thompson, J. E. 1987. Membrane deterioration in senescing carnation flowers: coordinated effects of phospholipid degradation and the action of membraneous lipoxygenase. Plant Physiol. 85:204-11
56. Fournier, J., Pelissier, B., Esquerre-Tugaye, M. T. 1986. Induction d'une activite lipoxygenase dans les cellules de tabac (Nicotiana tabacum) en culture, par des eliciteurs d'ethylene de Phytophthora parasitica var. nicotianae. C. R. Acad. Sci. Paris 303:651-54
57. Funk, C. D., Gunne, H., Steiner, H., Izumi, T., Samuelsson, B. 1989. Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system. Proc. Natl. Acad. Sci. USA 86:2592-96
58. Funk, C. D., Hoshiko, S., Matsumoto, T., Radmark, O., Samuelsson, B. 1989. Characterization of the human 5-lipoxygenase gene. Proc. Natl. Acad. Sci. USA 86:2587-91
59. Funk, M. O., Andre, J. C., Otsuki, T. 1987. Oxygenation of trans polyunsaturated fatty acids by lipoxygenase reveals steric features of the catalytic mechanism. Biochemistry 26:6880-84
60. Funk, M. O., Carroll, R. T., Thompson, J. F., Dunham, W. R. 1986. The lipoxygenases in developing soybean seeds, their characterization and synthesis in vitro. Plant Physiol. 82:1139-44
61. Funk, M. O., Carroll, R. T., Thompson, J. F., Sands, R. H., Dunham, W. R. 1990. Role of iron in lipoxygenase catalysis. J. Am. Chem. Soc. 112:5375-76
62. Funk, M. O., Whitney, M. A., Hausknecht, E. C., O'Brien, E. M. 1985. Resolution of the isozymes of soybean lipoxygenase using isoelectric focusing and chromatofocusing. Anal. Biochem. 146:246-51
63. Gaillard, T. 1978. Lipolytik and lipoxygenase enzymes in plants and their action in wounded tissues. In Biochemistry of Wounded Plant Tissues, ed. G. Kahl, pp. 155-201. Berlin: Walter de Gruyter
64. Galliard, T., Chan, H. W.-S. 1980. Lipoxygenases. In The Biochemistry of Plants, ed. P. K. Stumpf, E. E. Conn, 4:131-61. New York: Academic
65. Gallop, P. M., Paz, M. A., Fluckiger, R., Kagan, H. M. 1989. PQQ, the elusive coenzyme. Trends Biochem. Sci. 14:343-46
66. Gardner, H. W. 1979. Lipid hydroperoxide reactivity with proteins and amino acids: a review. J. Agric. Food Chem. 27:220-29
67. Garssen, G. J., Vliegenthart, J. F. G., Boldingh, J. 1971. An aerobic reaction between lipoxygenase, linoleic acid and its hydroperoxides. Biochem. J. 122: 327-32
68. Gibian, M. J., Singh, K. 1986. Irreversible inhibition of soybean lipoxygenase by phenyldiazine, autoxidizing phenylhydrazine and related materials. Biochim. Biophys. Acta 878:79-92
69. 2 uptake in wheat. Plant Physiol. 67:594-96
70. Grossman, S., Leshem, Y. Y. 1978. Lowering endogenous lipoxygenase activity in Pisum sativum foliage by cytokinin as related to senescence. Physiol. Plant. 43:359-62
71. Grossman, S., Zakut, R. 1979. Determination of the activity of lipoxygenase (lipoxidase). In Methods of Biochemical Analysis, ed. D. Glick, 3:303-29. New York: Wiley Interscience
72. Guss, P. L., Macko, V., Richardson, T., Stahmann, M. A. 1968. Lipoxidase in early growth of wheat. Plant Cell Physiol. 9:415-22
73. Hamberg, M. 1986. Isolation and structure of lipoxygenase from Saprolegnia parasitica. Biochim. Biophys. Acta 876:688-92
74. Hildebrand, D. F. 1989. Lipoxygenases. Physiol. Plant. 76:249-53
75. Hildebrand, D. F., Hamilton-Kemp, T. R., Legg, C. S., Bookjans, G. 1988. Plant lipoxygenases: occurrence, properties and possible functions. Curr. Top. Plant Biochem. Physiol. 7:201-19
76. Hildebrand, D. F., Hymowitz, T. 1981. Two soybean genotypes lacking lipoxygenase-1. J. Am. Oil Chem. Soc. 58: 583-86
77. Hildebrand, D. F., Hymowitz, T. 1982. Inheritance of lipoxygenase-1 activity in soybean seeds. Crop Sci. 22:851-53
78. Hildebrand, D. F., Hymowitz, T. 1983. Lipoxygenase activities in developing and germinating soybean seeds with and without lipoxygenase-1. Bot. Gaz. 144: 212-16
79. Hildebrand, D. F., Rodriguez, J. G., Legg, C. S., Brown, G. C., Bookjans, G. 1989. The effects of wounding and mite infestation on soybean leaf lipoxygenase levels. Z. Naturforsch. Teil C 44:655-59
80. Hildebrand, D. F., Snyder, K. M., Hamilton-Kemp, T. R., Bookjans, G., Legg, C. S., Andersen, R. A. 1989. Expression of lipoxygenase isozymes in soybean tissues. In Biological Role of Plant Lipids, ed. P. A. Biacs, K. Gruiz, T. Kremmer, pp. 51-56. New York: Plenum
81. Howell, N. 1989. Evolutionary conservation of protein regions in the protonmotive cytochrome b and their possible roles in redox catalysis. J. Mol. Evol. 29:157-69
82. Ikediobi, C. O., Chelvarajan, R. L., Ukoha, A. I. 1989. Biochemical aspects of wound healing in yams (Dioscorea spp). J. Sci. Food Agric. 48:131-39
83. Kacperska, A., Kubacka-Zebalska, M. 1985. Is lipoxygenase involved in the formation of ethylene from ACC? Physiol. Plant. 64:333-38
84. Kanofsky, J. R., Axelrod, B. 1986. Singlet oxygen production by soybean lipoxygenase isozymes. J. Biol. Chem. 261:1099-1104
85. Kar, M., Feierabend, J. 1984. Metabolism of activated oxygen in detached wheat and rye leaves and its relevance to the initiation of senescence. Planta 160:385-91
86. Kami, L., Prusky, D., Kobiler, I., Bar-Shira, E., Kobiler, D. 1989. Involvement of epicatechin in the regulation of lipoxygenase activity during activation of quiescent Colletotrichum gloeosporioides infections of ripening avocado fruits. Physiol. Mol. Plant Pathol.. 35:367-74
87. Kende, H. 1989. The enzymes of ethylene biosynthesis. Plant Physiol. 91:1-4
88. Keppler, L. D., Novacky, A. 1986. Involvement of membrane lipid peroxidation in the development of a bacterially induced hypersensitive reaction. Phytopathology 76:104-8
89. Kitamura, K. 1984. Biochemical characterization of lipoxygenase-lacking mutants, L-1-less, L-2-less, and L-3-less soybeans. Agric. Biol. Chem. 48:2339-46
90. Kitamura, K., Davies, C. S., Kaizuma, N., Nielsen, N. C. 1983. Genetic analysis of a null-allele for lipoxygenase-3 in soybean seeds. Crop Sci. 23:924-27
91. Klein, B. P., Cohen, B.-S., Grossman, S., King, D., Malovany, H., Pinsky, A. 1985. Effect of modification of soybean lipoxygenase-1 with N-bromosuccinimide on linoleate oxidation, pigment bleaching and carbonyl production. Phytochemistry 24:1903-6
92. Knofel, H. D., Bruckner, C., Kramell, R., Sembdner, G., Schreiber, K. 1984. A radioimmunoassay for jasmonic acid. Biochem. Physiol. Pflanzen. 179:317-25
93. Komaromy, M. C., Schotz, M. C. 1987. Cloning of rat hepatic lipase cDNA: evidence for a lipase gene family. Proc. Natl. Acad. Sci. USA 84:1526-30
94. Kubacka-Zebalska, M., Kacperska-Palacz, A. 1980. Lipoxygenase, an enzyme involved in plant growth? Physiol. Veg. 18:339-47
95. Kyte, J., Doolittle, R F. 1982. A simple method for displaying the hydrophobic character of a protein. J. Mol. Biol. 157:105-32
96. Leibowitz, M. E., Johnson, M. C. 1971. Relation of lipid peroxidation to loss of cations trapped in liposomes. J. Lipid Res. 12:662-70
97. Leshem, Y. Y. 1988. Plant senescence processes and free radicals. Free Radic. Biol. Med. 5:39-49
98. Leshem, Y. Y., Barness, G. 1982. Lipoxygenase as affected by free radical metabolism: senescence retardation by the xanthine oxidase inhibitor allopurinol. In Biochemistry and Metabolism of Plant Lipids, ed. J. F. G. M. Wintermans, P. J. C. Kuiper, pp. 275-78. Amsterdam: Elsevier
99. Leshem, Y. Y., Grossman, S., Frimer, A., Ziv, J. 1979. Endogenous lipoxygenase control and lipid-associated free radical scavenging as modes of cytokinin action in plant senescence retardation. In Advances in the Biochemistry and Physiology of Plant Lipids, ed. L. A. Appelqvist, C. Liljenberg, pp. 193-98. Amsterdam: Elsevier
100. Leshem, Y. Y., Wurzburger, J., Grossman, S., Frimer, A. A. 1981. Cytokinin interaction with free radical metabolism and senescence: effects on endogenous lipoxygenase and purine oxidation. Physiol. Plant. 53:9-12
101. Lieberman, M. 1979. Biosynthesis and action of ethylene. Annu. Rev. Plant Physiol. 30:533-91
102. Lupu, R., Grossman, S., Cohen, Y. 1980. The involvement of lipoxygenase and antioxidants on pathogenesis of powdery mildew on tobacco plants. Physiol. Plant Pathol. 16:241-48
103. Lynch, D. V., Thompson, J. E. 1984. Lipoxygenase-mediated production of superoxide anion in senescing plant tissue. FEBS Lett. 173:251-54
104. Mack, A. J., Peterman, T. K., Siedow, J. N. 1987. Lipoxygenase isozymes in higher plants: biochemical properties and physiological role. Isozymes: Curr. Top. Biol. Med. Res. 13:127-54
105. Matsui, K., Kajiwara, T., Hayashi, K., Hatanaka, A. 1988. Tissue specific heterogeneity of lipoxygenase in cucumber seedlings. Agric. Biol. Chem. 52: 3219-21
106. Matsumoto, T., Funk, C. D., Radmark, O., Hoog, J.-O., Jornvall, H., Samuelsson, B. 1988. Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc. Natl. Acad. Sci. USA 85:26-30
107. Meyer, A., Miersch, O., Buttner, C., Dathe, W., Sembdner, G. 1984. Occurrence of the plant growth regulator jasmonic acid in plants. J. Plant Growth Regul. 3:1-8
108. Miller, M. G., Obendorf, R. L. 1981. Use of tetraethylthiuram disultide to discriminate between alternative respiration and lipoxygenase. Plant Physiol. 67: 962-64
109. Navaratnam, S., Feiters, M. C., Al-Hakim, M., Allen, J. C., Veldink, G. A., Vliegenthart, J. F. G. 1988. Iron environment in soybean lipoxygenase-1. Biochim. Biophys. Acta 956:70-76
110. Nordlund, P., Sjoberg, B.-M., Eklund, H. 1990. Three-dimensional structure of the free radical protein of ribonucleotide reductase. Nature 345:593-98
111. Nugteren, D. H. 1975. Arachidonate lipoxygenase in blood platelets. Biochim. Biophys. Acta 380:299-307
112. Ocampo, C. A., Moerschbacher, B., Grambow, H. J. 1986. Increased lipoxygenase activity is involved in the hypersensitive response of wheat leaf cells infected with avirulent rust fungi or treated with fungal elicitor. Z. Naturforsch. Teil C 41:559-63
113. Oelze-Karow, H., Schopfer, P., Mohr, H. 1970. Phytochrome-mediated repression of enzyme synthesis (lipoxygenase: a threshold phenomenon). Proc. Natl. Acad. Sci. USA 65:51-57
114. Ohta, H., Ida, S., Mikami, B., Monta, Y. 1986. Changes in lipoxygenase components of rice seedlings during germination. Plant Cell Physiol. 27:911-18
115. Pages, M., Rosello, J., Casas, J., Gelpi, E., Gualde, N., Rigaud, M. 1986. Cyclooxygenase and lipoxygenase-like activity in Drosophilia melanogaster. Prostaglandins 32:729-40
116. Park, T. K., Polacco, J. C. 1989. Distinct lipoxygenase species appear in the hypocotyl/radicle of germinating soybean. Plant Physiol. 90:285-90
117. Pauls, K. P., Thompson, J. E. 1984. Evidence for the accumulation of peroxidized lipids in membranes of senescing cotyledons. Plant Physiol. 75: 1152-57
118. Peary, J. S., Prince, T. A. 1990. Floral lipoxygenase: activity during senescence and inhibition by phenidone. J. Am. Soc. Hort. Sci. 115:455-57
119. Peever, T. L., Higgins, V. J. 1989. Electrolyte leakage, lipoxygenase, and lipid peroxidation induced in tomato leaf tissue by specific and nonspecific elicitors from Cladosporium fulvum. Plant Physiol. 90:867-75
120. Peterman, T. K., Siedow, J. N. 1983. Structural features required for inhibition of lipoxygenase-2 by propyl gallate. Plant Physiol. 71:55-58
121. Peterman, T. K., Siedow, J. N. 1985. Behavior of lipoxygenase during establishment, senescence, and rejuvenation of soybean cotyledons. Plant Physiol. 78:690-95
122. Peterman, T. K., Siedow, J. N. 1985. Immunological comparison of lipoxygenase isozymes-1 and -2 with soybean seedling lipoxygenases. Arch. Biochem. Biophys. 238:476-83
123. Pirrung, M. C. 1986. Mechanism of a lipoxygenase model for ethylene biosynthesis. Biochemistry 25:114-19
124. Pistorius, E. K., Axelrod, B. 1974. Iron, an essential component of lipoxygenase. J. Biol. Chem. 249:3183-86
125. Pistorius, E. K., Axelrod, B., Palmer, G. 1976. Evidence for participation of iron in lipoxygenase reaction from optical and electron spin resonance studies. J. Biol. Chem. 251:7144-48
126. Ponz, F., Breuning, G. 1986. Mechanisms of resistance to plant viruses. Annu. Rev. Phytopathol. 24:355-81
127. Prusky, D., Kobiler, I., Jacoby, B., Sims, J. J., Midland, S. L. 1985. Inhibitors of avocado lipoxygenase: their possible relationship with the latency of Colletotrichum gloeosporioides. Physiol. Plant Pathol. 27:269-79
128. Que, L. 1980. Non-heme iron dioxygenases. Struct. Bond. 40:39-72
129. Ramadoss, C. S., Axelrpd, B. 1982. High performance liquid Chromatographic separation of lipoxygenase isozymes in crude soybean extracts. Anal. Biochem. 127:25-31
130. Ramadoss, C. S., Pistorius, E. K., Axelrod, B. 1978. Coupled oxidation of carotene by lipoxygenase requires two isozymes. Arch. Biochem. Biophys. 190:549-52
131. Rhoads, D. M., McIntosh, L. 1991. Isolation and characterization of a cDNA clone encoding an alternative oxidase protein of Sauromatum guttatum (Shott). Proc. Natl. Acad. Sci. USA. In press
132. Rustin, P., DuPont, J., Lance, C. 1983. Involvement of lipid peroxy radicals in the cyanide-resistant electron transport pathway. Physiol. Veg. 22:643-63
133. Ruzicska, P., Combos, Z., Farkas, G. L. 1983. Modification of the fatty acid composition of phospholipids during the hypersensitive reaction in tobacco. Virology 128:60-64
134. Ryan, C. A. 1987. Oligosaccharide signaling in plants. Annu. Rev. Cell Biol. 3:295-317
135. Ryan, C. A. 1988. Oligosaccharides as recognition signals for the expression of defensive genes in plants. Biochemistry 27:8879-83
136. Samuelsson, B., Dahlen, S.-E., Lindgren, J. A., Rouzer, C. A., Serhan, C. N. 1987. Leucotrienes and lipoxins: structures, biosynthesis and biological effects. Science 237:1171-76
137. Saniewski, M., Czapski, J. 1985. Stimulatory effect of methyl jasmonate on the ethylene production in tomato fruits. Experientia 41:256-57
138. Schechter, G., Grossman, S. 1983. Lipoxygenase from baker's yeast: purification and properties. Int. J. Biochem. 15:1295-304
139. Schewe, T., Halangk, W., Hiebsch, C., Rapoport, S. M. 1975. A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria. FEBS Lett. 60:149-52
140. Schewe, T., Rapoport, S. M., Kuhn, H. 1986. Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases. Adv. Enzymol. Mol. Biol. 58:191-272
141. Sheriff, S., Hendrickson, W. A., Smith, J. L. 1987. Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution. J. Mol. Biol. 197:273-96
142. Shibata, D., Steczko, S., Dixon, J. E., Andrews, P. C., Hermodson, M., Axelrod, B. 1988. Primary structure of soybean lipoxygenase-2. J. Biol. Chem. 263:6816-21
143. Shibata, D., Steczko, J., Dixon, J. E., Hermodson, M., Yazdanparast, R., Axelrod, B. 1987. Primary structure of soybean lipoxygenase-1. J. Biol. Chem. 262:10080-5
144. Siedow, J. N., Berthold, D. A. 1986. The alternative oxidase: A cyanide-resistant respiratory pathway in higher plants. Physiol. Plant. 66:569-73
145. Siedow, J. N., Girvin, M. E. 1980. Alternative respiratory pathway: its role in seed respiration and its inhibition by propyl gallate. Plant Physiol. 65:669-74
146. Sigal, E., Craik, C. S., Highland, E., Grunberger, D., Costello, L. L., et al. 1988. Molecular cloning and primary structure of human 15-lipoxygenase. Biochem. Biophys. Res. Commun. 157: 457-64
147. Slappendel, S., Malmstrom, B. G., Petersson, L., Ehrenberg, A., Veldink, G. A., Vliegenthart, J. F. G. 1982. On the spin and valence state of iron in native soybean lipoxygenase-1. Biochem. Biophys. Res. Commun. 108:673-77
148. Slappendel, S., Veldink, G. A., Vliegenthart, J. F. G., Aasa, R., Malmstrom, B. G. 1981. EPR spectroscopy of soybean lipoxygenase-1. Description and quantification of the high-spin Fe(III) signals. Biochim. Biophys. Acta 667:77-86
149. Spaapen, L. J. M., Verhagen, J., Veldink, G. A., Vliegenthart, J. F. G. 1980. The effect of modification of sulfhydryl groups in soybean lipoxygenase-1. Biochim. Biophys. Acta 618:153-62
150. Stallings, W. C., Kroa, B. A., Carroll, R. T., Metzger, A. L., Funk, M. O. 1990. Crystallization and preliminary X-ray characterization of a soybean seed lipoxygenase. J. Mol. Biol. 211:685-87
151. Start, W. G., Ma, Y., Polacco, J. C., Hildebrand, D. F., Freyer, G. A., Altschuler, M. 1986. Two soybean seed lipoxygenase nulls accumulate reduced levels of lipoxygenase transcripts. Plant Mol. Biol. 7:11-23
152. Staswick, P. E. 1990. Novel regulation of vegetative storage protein genes. Plant Cell 2:1-6
153. Steczko, J., Muchmore, C. R., Smith, J. L., Axelrod, B. 1990. Crystallization and preliminary X-ray investigation of lipoxygenase-1 from soybeans. J. Biol. Chem. 265:11352-54
154. Stegink, S. J., Siedow, J. N. 1986. Ethylene production from 1-aminocyclopropane-1-carboxylic acid in vitro: a mechanism for explaining ethylene production by a cell-free preparation from pea epicotyls. Physiol. Plant. 66:625-31
155. Sumner, J. B., Sumner, R. J. 1940. The coupled oxidation of carotene and fat by carotene oxidase. J. Biol. Chem. 134: 531-33
156. Tappel, A. L. 1961. Biocatalysts: lipoxidase and hematin compounds. In Autoxidation and Antioxidants, ed. W. O. Lundberg, pp. 325-66. New York: Interscience
157. Theorell, H., Holman, R. T., Akeson, A. 1947. Crystalline lipoxidasc. Acta Chem. Scand. 1:571-76
158. Thomas, H., Stoddart, J. L. 1980. Leaf senescence. Annu. Rev. Plant Physiol. 31:83-111
159. Thompson, J. E., Paliyath, G., Brown, J. H., Duxbury, C. L. 1987. The involvement of activated oxygen in membrane deterioration during senescence. In Plant Senescence, ed. W. W. Thompson, E. A. Nothnagel, R. C. Huffaker, pp. 146-55. Rockville: Am. Soc. Plant Physiol.
160. Trop, M., Grossman, S., Veg, Z. 1974. The antigenicity of lipoxygenase from various plant sources. Ann. Bot. 38:783-94
161. Ueda, J., Kato, J. 1980. Isolation and identification of a senescence-promoting substance from wormwood (Anemesia absinthium L.). Plant Physiol. 66:246-49
162. Ueda, J., Kato, J. 1982. Identification of jasmonic acid and abscisic acid as senescence-promoting substances from Cleyera ochnacea. Agric. Biol. Chem. 46:1975-76
163. van der Meer, R. A., Duine, J. A. 1988. Pyrroloquinoline quinone (PQQ) is the organic cofactor in soybean lipoxygenase-1. FEBS Lett. 235:194-200
164. van der Meer, R. A., Jongejan, J. A., Duine, J. A. 1987. Phenylhydrazine as a probe for cofactor identification in amine oxidoreductases. FEBS Lett. 221:299-304
165. van der Meer, R. A., Jongejan, J. A., Duine, J. A. 1988. Dopamine β-hydroxylase from bovine medulla contains covalently-bound pyrroloquinoline quinone. FEBS Lett. 231:303-7
166. Veldink, G. A., Boelens, H., Maccarrone, M., van der Lecq, F., Vliegenthart, J. F. G., et al. 1990. Soybean lipoxygenase-1 is not a quinoprotein. FEBS Lett. 270:135-38
167. Veidink, G. A., Vliegenthart, J. F. G. 1985. Lipoxygenases, nonheme iron-containing enzymes. Adv. Inorg. Biochem. 6:139-61
168. Veldink, G. A., Vliegenthart, J. F. G., Boldingh, J. 1977. Plant lipoxygenases. Prog. Chem. Fats Other Lipids 15:131-66
169. Verhue, W. M., Francke, A. 1972. The heterogeneity of soyabean lipoxygenase. Biochim. Biophys. Acta 284:43-53
170. Vernooy-Gerritsen, M., Veldink, G. A., Vliegenthart, J. F. G. 1982. Specificities of antisera directed against soybean lipoxygenases-1 and -2 and purification of lipoxygenase-2 by affinity chromatography. Biochim. Biophys. Acta 708:330-34
171. Vick, B. A., Zimmerman, D. C. 1976. Lipoxygenase and hydroperoxide lyase in germinating watermelon seedlings. Plant Physiol. 57:780-88
172. Vick, B. A., Zimmerman, D. C. 1979. Substrate specificity for the synthesis of cyclic fatty acids by a flaxseed extract. Plant Physiol. 63:490-94
173. Vick, B. A., Zimmerman, D. C. 1982. Levels of oxygenated fatty acids in young corn and sunflower plants. Plant Physiol. 69:1103-8
174. Vick, B. A., Zimmerman, D. C. 1983. The biosynthesis of jasmonic acid: a physiological role for plant lipoxygenase. Biochem. Biophys. Res. Commun. 111:470-77
175. Vick, B. A., Zimmerman, D. C. 1984. Biosynthesis of jasmonic acid by several plant species. Plant Physiol. 75:458-61
176. Vick, B. A., Zimmerman, D. C. 1987. Oxidative systems for modification of fatty acids: the lipoxygenase pathway. In The Biochemistry of Plants, ed. P. K. Stumpf, E. E. Conn, 9:53-90. Orlando: Academic
177. Wang, N., Southan, C., DeWolf, W. E., Wells, T. N. C., Kruse, L. I., Leatherbarrow, R. J. 1990. Bovine dopamine-hydroxylase, primary structure determined by cDNA cloning and amino acid sequencing. Biochemistry 29:6466-74
178. Weidhase, R. A., Kramell, H., Lehmann, J., Liebisch, H., Lerbs, W., Parthier, B. 1987. Methyl jasmonate-induced changes in the polypeptide pattern of senescing barley leaf segments. Plant Sci. 51:177-86
179. Whittaker, J. W., Solomon, E. I. 1988. Spectroscopic studies on ferrous nonheme iron active sites: magnetic circular dichroism of mononuclear Fe sites in superoxide dismutase and lipoxygenase. J. Am. Chem. Soc. 110:5329-39
180. Wion, K. L., Kirchgessner, T. G., Lusis, A. L., Schotz, M. C., Lawn, R. M. 1987. Human lipoprotein lipase complementary DNA sequence. Science 235:1638-41
181. Yabuuchi, S., Lister, R. M., Axelrod. B., Wilcox, J. R., Nielsen, N. C. 1982. Enzyme-linked immunosorbent assay for the determination of lipoxygenase isozymes in soybean. Crop Sci. 22:333-37
182. Yamamoto, H., Tani, T. 1986. Possible involvement of lipoxygenase in the mechanism of resistance of oats Avena sativa to Puccinia coronata pv avenae. Jpn. J. Phytopathol. 116:329-37
183. Yamane, H., Sugawara, J., Suzuki, Y., Shimamura, E., Takahashi, N. 1980. Synthesis of jasmonic acid related compounds and their structure-activity relationships on the growth of rice seedlings. Agric. Biol. Chem. 44:2857-64
184. Yang, S. F., Hoffman, N. E. 1984. Ethylene biosynthesis and its regulation in higher plants. Annu. Rev. Plant Physiol. 35:155-89
185. Yenofsky, R. L., Fine, M., Liu, C. 1988. Isolation and characterization of a soybean (Glycine max) lipoxygenase-3 gene. Mol. Gen. Genet. 211:215-22
186. Yoshimoto, T., Suzuki, H., Yamamoto, S., Takai, T., Yokoyama, C., Tanabe, T. 1990. Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes. Proc.Natl. Acad. Sci. USA 87:2142-46
187. Zimmerman, D. C., Coudron, C. A. 1979. Identification of traumatin, a wound hormone, as 12-oxo-trans-10-dodecenoic acid. Plant Physiol. 63:536-41
188. Zimmerman, D. C., Vick, B. A. 1973. Lipoxygenase in Chlorella pyrenoidosa. Lipids 8:264-66