Preparation of polymer-bound 1H-benzotriazoIe, a new potential scaffold for the compilation of organic molecule libraries

Journal of Combinatorial Chemistry

Volumn 1, Issue 2, 1999, Pages 173-176

  Katritzky, Alan R ^a   Belyakov, Sergei A ^b   Tymoshenko, Dmytro O ^a  

^a University of Florida ^*  (United States)

^b GUILFORD PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000305565     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc980034r     Document Type: Article

References (7)

1. Kalir, R.; Warshawsky, A.; Fridkin, M.; Patchornik, A. New Useful Reagents for Peptide Synthesis. Insoluble Active Esters of Polystyrene-Bound 1-HydroxybenzotriazoIe. Eur. J. Biochem. 1975, 59, 55-61.
2. (a) Pop, I. E.; Deprez, B. P.; Tartar, A. L. Versatile Acylation of N-Nucleophiles Using a New Polymer-Supported 1-Hydroxybenzo-triazole derivative. J. Org. Chem. 1997, 62, 2594-2603.
3. (b) Dendrinos, K. G.; Kalivretenos, A. G. Synthesis of W-Hydroxysuccinimide Esters Using Polymer Bound HOBT. Tetrahedron Lett. 1998, 39, 1321-1324.
4. (c) Dendrinos, K. G.; Jeong, J.; Huang, W.; Kalivretenos, A. G. HOBT immobilized on macroporous polystyrene beads: a useful reagent for the synthesis of amides. J. Chem. Soc., Chem. Commun. 1998, 499-500.
5. (a) Katritzky, A. R.; Lan, X.; Yang, J. Z.; Denisko, O. V. Properties and Synthetic Utility of N-Substituted Benzotriazoles. Chem. Rev. 1998, 98, 409-548.
6. (b) Katritzky, A. R.; Belyakov, S. A. Benzotriazole-Based Intermediates: Reagents for Efficient Organic Synthesis. Aldrichim. Acta 1998, 31, 35-45.
7. The benzotriazole resin described in this article will be available from Novabiochem from the middle of 1999.